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Medicine

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Big-Data Analysis Points Toward New Drug Discovery Method

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

Medicine

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pain, Narcotic, Opioid, Oxycodone

4 of 5 Mayo Opioid Prescriptions After Surgery Exceeded Upcoming Guidelines

More than 4 in 5 opioid prescriptions given after surgery over a recent two-year period at Mayo Clinic exceeded guidelines now in the works, the clinic’s researchers have found.

Medicine

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CPR, Cardiac Arrest

Drug Delivered During CPR May Improve Survival for Heart Attack

Researchers at the University of Illinois at Chicago have received a $1.2 million four-year grant from the National Institutes of Health to investigate new biological agents that mimic the effects of cooling when given during and after CPR.

Medicine

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Psychiatry, antidepressant drugs , Pregnancy, antidepressants and pregnancy, Intellectual Disability

Mount Sinai Researchers Find No Statistically Significant Risk of Intellectual Disability in Children Born to Mothers Treated with Antidepressants

In a first-of its kind study, researchers from the Icahn School of Medicine at Mount Sinai found an elevated risk of intellectual disability (ID) in children born to mothers treated with antidepressants, but the risk was not statistically significant and is likely due to other factors, including parental age and the parents’ psychiatric history.

Medicine

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Antibiotic Resistance, Stewardship, Dermatology

Skin in the Game: Dermatology’s Role in Antibiotic Stewardship

While discussions on stewardship are often focused on fighting infection among the sickest patients, those aren’t the only people taking these drugs. Data from the CDC shows the average dermatology provider wrote 669 antibiotic prescriptions in 2014, the most recent year for which data are available. That is, by far, the highest average of any provider specialty. For some perspective, the next closest group was primary care physicians, who wrote an average of 483 prescriptions per provider. It begs the question of whether dermatology should be under the microscope when it comes to stewardship.

Medicine

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IBD, Inflammatory Bowel Disease, Colitis, Microbiome, Antibiotics

Antibiotics Taken Late in Pregnancy Can Increase Risk for Inflammatory Bowel Diseases in Offspring

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

Medicine

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Kimmel Cancer Center, Eric H. Raabe, Eric Raabe, Cancer, TAK228 , Chemotherapy

Experimental "Enhancer" Drug May Boost Conventional Therapies for Deadly Pediatric Brain Cancers

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Laboratory studies suggest that an experimental drug already in early clinical trials for a variety of adult cancers might enhance radiation and chemotherapy for two childhood brain cancers that currently are virtually always fatal.

Medicine

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Sunburn, Photosensitivity, Pharmacy, Ultravioet, Antibiotic, Antidepressant, Medicine, Side Affects

Intense Sunburn: What Medicines Are You Taking?

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Known as drug-induced photosensitivity, the condition affects people taking prescribed medications and mimics intense sunburns with severe pain, skin peeling and blistering. People taking antibiotics and antidepressants are most at risk.

Science

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Ut Southwestern, Pharmaceuticals, Biochemistry

Researchers Report Chemical Reaction with Potential to Speed Drug Development

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Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations. UT Southwestern researchers have hit upon a novel way to do that.

Medicine

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Mark Bicket, per, Drugs, Opiod

Researchers Find Handwritten Opioid Prescriptions Are More Prone to Mistakes

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In a small study of opioid prescriptions filled at a Johns Hopkins Medicine outpatient pharmacy, researchers found that handwritten orders for the drugs contribute heavily to a trio of prescribing and processing errors in contrast to those created electronically.







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