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Medicine

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chemotherapeutic agents, Capecitabine, Generic Drug, Health Care Costs

Savings Less Than Expected for Generic Oral Chemotherapy

Cost savings fell below expectations for generic versions of an orally administered cancer treatment in an analysis by University of North Carolina Lineberger Comprehensive Cancer Center researchers. The findings raise questions about the extent to which generic drugs can help control care costs for cancer treatments.

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genes, gene synthesis, Genetics, DNA, DNA assembly, Cancer, organ growth, Genome, Enzymes, Epigenetics

Revolutionary Process Could Signal New Era for Gene Synthesis

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A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis – a vital research tool with real-world applications in everything from growing transplantable organs to developing treatments for cancer.

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Study Unlocks How Changes in Gene Activity Early During Therapy Can Establish the Roots of Drug-Resistant Melanoma

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A UCLA-led study of changes in gene activity in BRAF-mutated melanoma suggests these epigenomic alterations are not random but can explain how tumors are already developing resistance as they shrink in response to treatment with a powerful class of drugs called MAP kinase (MAPK)-targeted inhibitors.

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Heart Disease, Cardiology, Family History, heart attacks, Research, Ut Southwestern

South Asians with Family History of Heart Disease at Greater Risk

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New research by UT Southwestern cardiologists shows that people of South Asian descent with a family history of coronary heart disease are significantly more likely to have high levels of calcium buildup in their arteries – an indicator of higher risk for heart attacks.

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Children's Anxiety, Thriving After Cancer, Unnecessary Antibiotics, and More in the Children's Health News Source

Click here for the latest research and features on Children's Health.

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Uniformed Services University, Uniformed Services University Of The Health Sciences

Genome Sequence Is Not a Predictor of Radiation Resistance

Bethesda, Md. – For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka “Conan the bacterium,” can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

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University of Utah Health Collaborates with Janssen Research & Development to Investigate the Genetics of Suicide

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Researchers at the University of Utah Health are collaborating with Janssen Research & Development, LLC (“Janssen”) to identify genetic variations associated with an increased risk for suicide.

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Four Grants in Four Days

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ZOWEEEE!! Kennesaw State University’s Office of Research recorded a big first: 4 DIFFERENT researchers garnered 4 NSF grants over 4 days. “This is a really cool story for us,” said Jonathan McMurry, associate vice president for research. “It was almost surreal, every day a new grant coming in!”

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Penn Medicine, Telomeres, Perelman School of Medicine at the University of Pennsylvania, Muscular Dystrophy Research

Researchers Find Shortened Telomeres Linked to Dysfunction in Duchenne Muscular Dystrophy

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Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment. In a study published today online in Stem Cell Reports, researchers found that stem cells in the muscles of muscular dystrophy patients may, at an early age, lose their ability to regenerate new muscle, due to shortened telomeres

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Human Genetics Studies Reveal New Targets to Reduce Heart Disease

Again and again, it’s the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.







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