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Medicine

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blood-brain barrier, Allan-Herndon-Dudley syndrome, Clive Svendsen

Scientists Show How Defects in Blood-Brain Barrier Could Cause Neurological Disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome. The findings point to a path for treating this syndrome and hold promise for analyzing other neurological diseases.

Medicine

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Endothelial Cells, Huntington’s disease, Blood Vessels

Basis of ‘Leaky’ Brain Blood Vessels in Huntington’s Disease Identified

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington’s disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

Medicine

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Psychology, Bruce Compas, Vanderbilt, Children, Chronic Illness, Cancer, Leukaemia, Leukemia, Brain Tumor, Sickle Cell Anemia, Congenital Heart Disease, Type 1 Diabetes, Traumatic Brain Injury, Memory, IQ, PTSD, Chemotherapy, Radiation, Vumc, mental therapy, mental and cognitive disorders

Sick Kids Live Longer, but Brain Function May Suffer

Hundreds of thousands of children with chronic illnesses who used to die are now surviving their disease and treatment—which is amazing. But their brains are being damaged in the process of keeping them alive. This first ever research quantifies the IQ impact of six main illnesses and looks and the common threads that connect them. It also takes next steps on how psychologists can team up with surgeons/oncologists, etc. to help treat kids and their parents, so they can thrive in school and life.

Medicine

Channels:

biomarkers, Saliva, Alzheimber's Disease, Metabolomics, Diagnostic Biomarker, noninvasive test, Metabolites, Dementia, dementia prevention, Journal Of Alzheimer's Disease, Screening

Diagnostic Biomarkers in Saliva Show Promise in Recognizing Early Alzheimer’s Disease

Beaumont Research Institute investigators are hopeful that their study involving small molecules in saliva will help identify those at risk of developing Alzheimer’s disease.

Medicine

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zika virus, Protease, NS3, NS2B, Inhibitors

New Zika Virus Inhibitor Identified

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Compound could serve as basis for drugs to prevent neurological complications of Zika

Medicine

Channels:

Stem Cells, Diseases, Pharmaceuticals, Brain, Neurological Deficits, Thyroid Hormone

Patient’s cells used to replicate dire developmental condition

A team of scientists from the University of Wisconsin-Madison and Cedars-Sinai in Los Angeles have used the cells of AHDS patients to recreate not only the disease, but a mimic of the patient’s blood-brain barrier in the laboratory dish using induced pluripotent stem cell technology.

Medicine

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Multiple Sclerosis (MS), Neurology, smartphone app, Research Trial, 23andMe, MRI, Tech, app development, Pilot Study, USC, University Of Southern California, Keck Medicine of USC, Keck School Of Medicine, Genetics, Health Care Technology, Technology, MS, Daniel Pelletier

Unlocking the Mystery of Multiple Sclerosis with Tech

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Recruitment begins for a Keck School of Medicine of USC study of the first smartphone app to combine clinical data, MRI imaging and genetic data for people with multiple sclerosis

Medicine

Science

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Moral Behavior, Moral Enhancement, Technology, Pharmaceticals, Surgery, Neurotechnology, Oxytocin, Amphetamine, SSRI, Beta Blockers, Transcranial Magnetic Stimulation, transcranial direct current stimulation, Deep Brain Stimulation, Research

Study: ‘Moral Enhancement’ Technologies Are Neither Feasible Nor Wise

A recent study finds that “moral enhancement technologies” – which are discussed as ways of improving human behavior – are neither feasible nor wise, based on an assessment of existing research into these technologies.

Medicine

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Ritalin, Attention Deficit Hyperactivity Disorder, ADHD, study enhancer, stimulant drugs, Methylphenidate, brain growth, Brain Development

Nonprescription Use of Ritalin Linked to Adverse Side Effects, UB Study Finds

New research from the University at Buffalo Research Institute on Addictions that explored the potential side effects of the stimulant drug Ritalin on those without ADHD showed changes in brain chemistry associated with risk-taking behavior, sleep disruption and other undesirable effects.

Medicine

Channels:

Multiple Sclerosis (MS), MS, Rehabiliation, Telemedicine, Telerehabilitation, lakeshore foundation, UAB, University of Alabama at Birmingham

UAB / Lakeshore Research Collaborative Awarded $5.8M for MS Research

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The grant will help fund a study to determine whether people with multiple sclerosis get as much benefit from an exercise-based rehabilitation program delivered via internet and telephone as they do when the therapy is provided in a clinic.







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