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  • Embargo expired:
    6-Jul-2018 2:00 PM EDT

Article ID: 696927

Scientists Identify a Protein Complex That Shapes the Destiny of T Cells

St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital scientists report the protein complex mTORC1 serves as a bridge between environmental signals and metabolic programs to influence the fate of developing T cells

Released:
2-Jul-2018 12:05 PM EDT
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Article ID: 697092

Scientists Identify Body’s Microreactors for Innate Immunity

UT Southwestern Medical Center

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body’s first response to infection, UT Southwestern researchers report.

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6-Jul-2018 11:05 AM EDT
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Article ID: 696897

New Model for Predicting Neuroblastoma Outcomes Incorporates Early Developmental Signals

Stowers Institute for Medical Research

Motivated by a desire to better understand the molecular circuitry underlying neuroblastoma and limitations of current methods for predicting disease progression and outcome, researchers from the Kulesa Lab at the Stowers Institute for Medical Research and collaborators at the University of Michigan and Oxford University set out to construct a logic-based model incorporating information about developmental signaling pathways implicated in the disease.

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6-Jul-2018 10:00 AM EDT
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  • Embargo expired:
    6-Jul-2018 9:00 AM EDT

Article ID: 696790

Breast Cancer Growth Signals Are Enhanced by a Protein Outside Cells

The Rockefeller University Press

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells. The study, “Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells,” will be published July 6 in the Journal of Cell Biology (JCB).

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28-Jun-2018 12:00 PM EDT
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Article ID: 697077

Nature’s Antifreeze Inspires Revolutionary Bacteria Cryopreservation Technique

University of Warwick

The survival mechanisms of polar fish have led scientists at the University of Warwick to develop of a revolutionary approach to ‘freeze’ bacteria.

Released:
6-Jul-2018 7:05 AM EDT
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  • Embargo expired:
    5-Jul-2018 5:00 PM EDT

Article ID: 696786

Researchers Develop Gene Therapy Method to Target Kidney Cells

American Society of Nephrology (ASN)

• A synthetic adeno-associated virus was highly efficient at delivering genetic material to different kidney cell types in mice and humans. • The viral vector was also successfully used in gene therapy strategies to treat mice with kidney scarring.

Released:
29-Jun-2018 9:00 AM EDT
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  • Embargo expired:
    5-Jul-2018 5:00 PM EDT

Article ID: 696963

Gene Therapy Method Developed to Target Damaged Kidney Cells

Washington University in St. Louis

Research led by Washington University School of Medicine in St. Louis has shown, in mice, that genetic material can be delivered to damaged cells in the kidneys, a key step toward developing gene therapy to treat chronic kidney disease. The potentially fatal condition affects 30 million Americans, most of whom don’t realize they have chronic kidney disease.

Released:
3-Jul-2018 9:00 AM EDT
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Article ID: 697042

Non-Opioid Drug Relieves Pain in Mice, Targets Immune Cells

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that inhibiting a receptor on immune cells called macrophages may help relieve pain in some patients, particularly those with chronic neuropathic pain, such as those with conditions like diabetic neuropathy.

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5-Jul-2018 1:30 PM EDT
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Article ID: 697039

Coriell Institute for Medical Research Earns Updated ISO 9001:2015 Certification for Quality Management

Coriell Institute for Medical Research

The Coriell Institute for Medical Research's quality managment system has been certified to the updated ISO 9001:2015 standards.

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5-Jul-2018 12:40 PM EDT
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Article ID: 697029

Precision Genomics Point the Way to Mutations Associated with Accelerated Aging

Mayo Clinic

Mayo Clinic researchers are using precision genomics to search for undiscovered, inheritable genetic mutations that cause accelerated aging. In a study recently published in Mayo Clinic Proceedings, researchers conducted a study assessing 17 patients with short telomere syndromes — rare conditions that result in premature DNA and cellular deterioration. The ability to pinpoint the genetic abnormalities associated with short telomere syndromes is key to finding better ways to screen, diagnose and treat patients.

Released:
5-Jul-2018 11:00 AM EDT
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