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Medicine

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AMUR, Leopard, Distemper, cat, wildlife disease

Canine Distemper Confirmed in Far Eastern Leopard, World’s Most Endangered Big Cat

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The Far Eastern or Amur leopard (Panthera pardus orientalis) is already among the rarest of the world’s big cats, but new research reveals that it faces yet another threat: infection with canine distemper virus (CDV).

Science

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Flu Shot, Influenza, Virus, Infectious Disease, Genetics, Interferons, Vaccines

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 18-Jan-2018 2:00 PM EST

Medicine

Science

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Drug Discovery, Drug Development, High-throughput screening, CD73 inhibitors, multiplex RF-MSMS Assay, immuno-oncology, laboratory automation

A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

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A new original research article in SLAS Discovery presents a fast, sensitive, and robust methodology for screening small molecule inhibitors against CD73/Ecto-5’-Nucleotidase, a promising target for developing anti-cancer drugs.

Medicine

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Atopic Dermatitis, Light, TNF super family, Fibrosis

LJI Researchers Discover Key Driver of Atopic Dermatitis

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La Jolla Institute scientists demonstrate that LIGHT, a member of the tumor necrosis factor (TNF) super family, directly controls the hyperproliferation of keratinocytes as well as the expression of periostin, a protein that contributes to the clinical features of atopic dermatitis as well as other inflammatory skin diseases such as scleroderma.

Medicine

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Study Advances Gene Therapy for Glaucoma

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In a study published today in the scientific journal Investigative Ophthalmology and Visual Science, Kaufman and Curtis Brandt, a fellow professor of ophthalmology and visual sciences at UW-Madison, showed an improved tactic for delivering new genes into the eye's fluid drain, called the trabecular meshwork. It could lead to a treatment for glaucoma.

Life

Social and Behavioral Sciences

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Abuse, Neglect, Childhood, Child Development, Adaptation, Adulthood, Psychology

Tracking the Impact of Early Abuse and Neglect

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Maltreatment experienced before age 5 can have negative effects that continue to be seen nearly three decades later, according to a new study led by Lee Raby, an assistant professor of psychology at the University of Utah.

Medicine

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Cancer, Immunotherapy, PDL1

Who Might Benefit From Immunotherapy? New Study Suggests Possible Marker

New research finds that PDL-1 expressed in antigen presenting cells – macrophages and dendritic cells found in the tumor microenvironment and in the nearby lymph nodes -- is a better indicator than PDL-1 in the tumor of who will respond to immunotherapy drugs.

Medicine

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Research, Surgery, Bariatric Surgery, Medical News, Feinberg School of Medicine

Bariatric Surgery Prolongs Lifespan in Obese

Obese, middle-age men and women who had bariatric surgery have half the death rate of those who had traditional medical treatment over a 10-year period, reports a study that answers questions about the long-term risk of the surgery. 

Medicine

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Smart phone apps, Pediatrics, Fetal Alcohol Spectrum Disorders , Alcohol Addiction

Smartphone App Now Recognizes FASD Thanks to MMI Geneticist

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With a smartphone and an app, qualified health care professionals can now diagnose fetal alcohol spectrum disorders (FASD) in their office thanks to a suggestion from Omar Rahman, M.D.

Science

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Opioid, opioid alternatives, pain, Molecular Biology, Neuroscience, RNA binding, mRNA

Researchers Devise Decoy Molecule to Block Pain Where It Starts

Dr. Zachary Campbell, who researches pain on the molecular level at the University of Texas at Dallas, recently published a study that describes a new method of reducing pain-associated behaviors with RNA-based medicine, creating a new class of decoy molecules that prevent the onset of pain.







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