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Science

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BOND, fiber optic strain sensors;, Reinforced Concrete, Shrinkage, tension stiffening, concrete blocks

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 3-May-2017 9:00 AM EDT

Business

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Democrat, Republican, IPO, PAC, political fundraising, political money contributions , Stock Market, Investment

Study Finds Political Contributions Can Play an Important Role in a Successful IPO

A firm’s political donations can have a significant effect on initial public offering (IPO) underpricing, leading to immediate and measurable gains on issue day, according to new research from the University of Portsmouth.

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Honey Bees

Common Pesticide Damages Honey Bee’s Ability to Fly

Biologists at UC San Diego have provided the first evidence that a widely used pesticide can significantly impair the ability of otherwise healthy honey bees to fly. The study, which employed a bee “flight mill,” raises concerns about how pesticides affect honey bee pollination and long-term effects on the health of honey bee colonies.

Medicine

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Neuropathies, Peripheral Nervous System, peripheral nerve sheath tumors, NF1, Nature Communications, Cincinnati Children's Hospital Medical Center, Myelin Sheath, Pediatrics, press release, press release distribution, n, News Media

HIPPO’s Molecular Balancing Act Helps Nerves Not Short Circuit

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Scientists report in Nature Communications it may be possible to therapeutically fine tune a constantly shifting balance of molecular signals to ensure the body’s peripheral nerves are insulated and functioning normally. In a study published April 26, they suggest this may be a way to treat neuropathies or prevent the development of peripheral nerve sheath tumors. They discovered genetic dysfunction in the HIPPO-TAZ/YAP and Gαs-protein feedback circuit disrupts the balanced formation of the protective myelin sheath.

Science

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Ut Southwestern, Fatty Liver Disease, Obesity, Nafld, Pnpla3

Obesity Amplifies Genetic Risk of Nonalcoholic Fatty Liver Disease

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An international study based at UT Southwestern Medical Center revealed a striking genetic-environmental interaction: Obesity significantly amplifies the effects of three gene variants that increase risk of nonalcoholic fatty liver disease (NAFLD) by different metabolic pathways.

Medicine

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Cancer, Ovarian Cancer, Biomarker, Cancer Research, NY-ESO-1, Immunotherapy, Targeted Therapy, Tumor Antigens

Roswell Park-Led Team Identifies Tumor Marker for Aggressive Ovarian Cancer

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Patients who expressed the tumor antigen NY-ESO-1 had more aggressive cancers and were more likely to die early from their disease, according to a large study conducted by Roswell Park Cancer Institute researchers and published online ahead of print in the journal Gynecologic Oncology.

Medicine

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Scientists Unravel How Protein Impacts Intellectual Disability

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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a protein helps balance nerve cell communication.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 28-Apr-2017 2:00 PM EDT

Medicine

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Obesity, Type 2 Diabetes, Body Mass Index, Journal of the Endocrine Society, metabolic health, Children and Teens, Young Adults, Endocrinology, Diabetes, Diabetes & Endocrinology, Endocrine Society

Childhood Obesity Quadruples Risk of Developing Type 2 Diabetes

Children with obesity face four times the risk of developing type 2 diabetes compared to children with a body mass index (BMI) in the normal range, according to a study published in the Journal of the Endocrine Society.

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Paris Climate Agreement, Steven Davis, Fossil Fuels

India’s Outsized Coal Plans Would Wipe Out Paris Climate Goals

India will not be able to meet its Paris climate agreement commitments in the coming years if it carries through with plans to construct nearly 370 coal-fired power plants, according to University of California, Irvine and CoalSwarm researchers.







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