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Medicine

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Epilepsy, Cortex, Neurobiology

Researchers Identify Cause for Severe Pediatric Epilepsy Disorder

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Researchers at the University of California, San Diego School of Medicine have discovered that convulsive seizures in a form of severe epilepsy are generated, not on the brain's surface as expected, but from within the memory-forming hippocampus.

Medicine

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Neurology, Journal Neurology, Neurology, American Academy Of Neurology, AAN, Brain Shrinkage, Hippocampus, Alzheimer's Disease, Dementia, Cognitive Impairment, Brain Volume, Hippocampal Volume, Brain Atrophy, Memory Problems, Memory

Shrinking in Hippocampus Area of Brain Precedes Alzheimer's Disease

People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study published in the March 17, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.

Medicine

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Alzheimer's Disease, Diagnosis, Biomarker

Pathologists Pioneer Biomarker Test to Diagnose or Rule Out Alzheimer's Disease

A test capable of confirming or ruling out Alzheimer's disease has been validated and standardized by researchers at the University of Pennsylvania School of Medicine. By measuring cerebrospinal fluid (CSF) concentrations of two of the disease's biochemical hallmarks "“ amyloid beta42 peptide and tau protein "“ the test also predicted whether a person's mild cognitive impairment would convert to Alzheimer's disease over time.

Medicine

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Neuropathy, Chemotherapy, AXON, Cancer, Diabetes, Nerve, Degeneration

Blocking Protein May Help Ease Painful Nerve Condition

Scientists have identified the first gene that pulls the plug on ailing nerve cell branches from within the nerve cell, possibly helping trigger the painful condition known as neuropathy, which can afflict patients with cancer, diabetes, kidney failure and other disorders.

Medicine

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Neuroscience, Learning, Dopaminergic Neurons, Substantia Nigra

Penn Neuroscientists Find That The Unexpected Is A Key to Human Learning

The human brain's sensitivity to unexpected outcomes plays a fundamental role in the ability to adapt and learn new behaviors, according to a new study by a team of psychologists and neuroscientists from the University of Pennsylvania.

Medicine

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Neurodegenerative, Huntington’S Disease, Cortex, Cx929, Actin Polymerization, Ampakines, Ampa Receptor, Memory, Recognition, Dementia

Ampakines Reverse Memory Loss in Animal Model of Huntington's Disease

A study conducted by Prof. Gary Lynch at the University of California, Irvine, has demonstrated the remarkable reversal of memory loss in an animal model of Huntington's disease using a novel class of agents known as ampakines. The experiments were conducted in mice harboring the genetic mutation found in humans that is responsible for Huntington's disease.

Medicine

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Amyloid Beta, Alzheimer's Disease, Cerebrospinal Fluid (CSF), Impairment, Cognitive, Biomarker

Alzheimer's Marker Linked to Brain Damage

Researchers at Washington University School of Medicine in St. Louis have linked a potential indicator of Alzheimer's disease to brain damage in humans with no signs of mental impairment.

Medicine

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Neurology, Journal Neurology, Neurology, American Academy Of Neurology, AAN, Air Pollution, Weather, Trigger Headaches, Headache, Lower Barometric Air Pressure, Temperature, Barometric Pressure, Air Pollutant, Non Migraine Headaches, Migraines, Air Temper

Does Air Pollution or Weather Trigger Headaches?

A new study shows that higher temperatures and lower barometric air pressure may lead to a higher, short-term risk of headaches, but air pollution may not have a significant effect on headache. The research is published in the March 10, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.

Medicine

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Diabetes, Cholesterol, Alzheimer's Disease, Cognitive Decline, Apoe ε4, Ldl Cholesterol, Memory, Vascular, Heart Disease, Stroke, Washington Heights/Inwood Columbia Aging Project, Smoking, Hypertension, Oxidative Stress, Inflammation, Neuron Tangles, Neurofibril

Diabetes & Elevated Cholesterol Linked to Faster Cognitive Decline in Alzheimer's

A history of diabetes and elevated levels of cholesterol, especially LDL cholesterol, are associated with faster cognitive decline in patients with Alzheimer's disease, according to a new study from Columbia University Medical Center researchers. These results add further evidence of the role of vascular risk factors in the onset and progression of Alzheimer's disease.

Medicine

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Metabolic, Neurological Disorders

Metabolic and Neurological Disorders May Share Common Risk Factors

Metabolic disorders such as obesity and diabetes appear to share risk factors with and may influence the development of Alzheimer's disease and other forms of dementia, according to several reports published in the March issue of Archives of Neurology, one of the JAMA/Archives journals.







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