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Medicine

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Biology, Biotechnology, Developmental Biology, Regenerative Medicine, gastrointestinal disease, Colon, Cell Biology, Genetics, human pluripotent stem cells, CELL STEM CELL, Cell Press , Science, Research, Cincinnati Children's Hospital Medical Center, National Institutes , Pediatrics, press release, press release distribution, Children

Lab Grown Human Colons Change Study of GI Disease

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Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell. The study is believed to be the first time human colon organoids have been successfully tissue engineered in this manner, according to researchers who led the project.

Medicine

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HIV, AIDS, Cytomegalovirus, Mother To Child Transmission, Infant, CMV, brain damage infants, Fetal Growth, Liver Damage, lung damage, spleen damage, Hearing Loss, HIV Positive Women

HIV-Positive Women with Cytomegalovirus Likelier to Pass Virus That Causes AIDS to Infant

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HIV-positive women with CMV in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV to their infants. The research also found that they are nearly 30 times likelier to transmit CMV to their infants.

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What Percentage of ALS Is Genetic?

Up to 90 percent of people with amyotrophic lateral sclerosis (ALS) report that they have no family history of the disease. Now, new research has found approximately 17 percent of such ALS cases may be caused by a gene mutation, according to a study published in the June 21, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Science

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heterochromatin, Genome, Cell Biology

Researchers Find New Mechanism for Genome Regulation

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The same mechanisms that separate mixtures of oil and water may also help the organization of an unusual part of our DNA called heterochromatin, according to a new study by Berkeley Lab researchers. They found that liquid-liquid phase separation helps heterochromatin organize large parts of the genome into specific regions of the nucleus. The work addresses a long-standing question about how DNA functions are organized in space and time, including how genes are silenced or expressed.

Medicine

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Next-generation sequencing panel , pediatric cancers, Comprehensive DNA and RNA Pediatric Cancer Panel

Children’s Hospital Los Angeles Launches OncoKidsSM – a Comprehensive DNA and RNA Pediatric Cancer Panel

Today, a team of investigators at Children’s Hospital Los Angeles launched OncoKidsSM, a next-generation sequencing-based panel specifically designed for pediatric cancers.

Science

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biological and environmental sciences, Grass, grasses, grasslands ecosystem, Grasslands, grasslands vegetation, Genetics, Genome, genome analysis, grass stomat, grass stomata, Joint Genome Institute, JGI, Plants, Genetic Advantage, Biofuels, Bio Fuels, FUEL, Crops, crop development, marginal farmland, Water, Carbon Dioxide

Grasses: The Secrets Behind Their Success

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Researchers find a grass gene affecting how plants manage water and carbon dioxide that could be useful to growing biofuel crops on marginal land.

Medicine

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Johnson & Johnson, Dr. Paul Janssen Award for Biomedical Research, Douglas Wallace, Champions of Science

Douglas Wallace, Ph.D., Wins 2017 Dr. Paul Janssen Award for Biomedical Research

Johnson & Johnson Launches Campaign for Champions of Science

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International Team Set to Evaluate New Advances in Hemophilia Treatment

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CoreHEM Project, is a multi-stakeholder partnership which will establish a core set of outcome measurements to be used to evaluate the comparative effectiveness of gene therapies in hemophilia.

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Selfish Gene Acts as Both Poison and Antidote to Eliminate Competition

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Researchers from the Stowers Institute for Medical Research in collaboration with Fred Hutchinson Cancer Research Center researchers have identified an unprecedented genetic survival strategy that would be right at home in an Agatha Christie murder mystery novel.

Medicine

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MYCN, Neuroblastoma, Pediatrics, Germline, Genetics

New Research Points to Potential for More Targeted Treatments of Deadly Neuroblastoma Tumors in Children

Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research by the University of Chicago Medicine. The findings lay the groundwork for developing more targeted treatments for particularly deadly variations of the cancer.







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