Feature Channels: Biotech

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Released: 5-Jul-2023 6:15 PM EDT
Dissolving cardiac device monitors, treats heart disease
Northwestern University

Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event. To help prevent those deaths, researchers at Northwestern and George Washington (GW) universities have developed a new device to monitor and treat heart disease and dysfunction in the days, weeks or months following such events.

Newswise: NUS pharmacists develop a “cheeky” and pain-free solution for drug delivery
Released: 3-Jul-2023 9:25 PM EDT
NUS pharmacists develop a “cheeky” and pain-free solution for drug delivery
National University of Singapore (NUS)

Conventional ways of administering medication – by swallowing tablets, consuming bitter syrups, injections or rectal insertions – could be distressing and unpleasant for some patients, especially young children or the elderly. A team of researchers led by Associate Professor Chan Sui Yung, Honorary Fellow at the Department of Pharmacy under the Faculty of Science at the National University of Singapore (NUS), has recently developed easy-to-use oral films that enable painless, efficient, and discreet drug administration.

Newswise: AI and CRISPR Precisely Control Gene Expression
30-Jun-2023 5:50 PM EDT
AI and CRISPR Precisely Control Gene Expression
Columbia University School of Engineering and Applied Science

The study by researchers at New York University, Columbia Engineering, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different ways—such as flicking a light switch to shut them off completely or by using a dimmer knob to partially turn down their activity. These precise gene controls could be used to develop new CRISPR-based therapies.

   
Released: 3-Jul-2023 8:50 AM EDT
NUS physicists utilise hair fluorescence to repurpose human hair waste
National University of Singapore (NUS)

Physicists from the National University of Singapore (NUS) have developed an innovative method of converting human hair waste into a functional material that can be used to encrypt sensitive information or detect environmental pollutants.

Newswise: June Research Highlights
Released: 30-Jun-2023 2:45 PM EDT
June Research Highlights
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for June 2023.

Released: 30-Jun-2023 2:20 PM EDT
New Preliminary Findings on Potential Response Indicator of Rakuten Medical's Alluminox Treatment from Phase 2 Window of Opportunity Study at SNMMI 2023
Rakuten Medical, Inc.

Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell targeting therapies based on its proprietary Alluminox™ platform, today announced that new interim evaluation data from the ASP-1929-103 study has been presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2023 Annual Meeting held from June 24 to 27.

Newswise: Computer Engineering Grads Design Assistive Glasses For People With Visual Impairments
Released: 29-Jun-2023 10:35 AM EDT
Computer Engineering Grads Design Assistive Glasses For People With Visual Impairments
California State University, Fullerton

To help people with visual impairments gain more independence, Cal State Fullerton computer engineering students developed assistive glasses, a hands-free wearable technology device. The glasses can help people with visual impairments detect and identify often-used objects — something a guide dog cannot always do.

   
Newswise: SLAS Technology Provides Insight into the Future of Bioprinting
Released: 29-Jun-2023 10:00 AM EDT
SLAS Technology Provides Insight into the Future of Bioprinting
SLAS

The June special issue of SLAS Technology showcases the latest developments in the field of biotechnology with its collection of seven research articles.

   
Newswise: All-in-one device for hemorrhage control
Released: 28-Jun-2023 2:55 PM EDT
All-in-one device for hemorrhage control
Terasaki Institute for Biomedical Innovation

A multi-faceted device for effectively treating deep, non-compressible, and irregularly-shaped wounds has been engineered by the scientists at the Terasaki Institute for Biomedical Innovation (TIBI).

Newswise: Newborn baby inspires sensor design that simulates human touch
Released: 28-Jun-2023 8:05 AM EDT
Newborn baby inspires sensor design that simulates human touch
Penn State Materials Research Institute

As we move into a world where human-machine interactions are becoming more prominent, pressure sensors that are able to analyze and simulate human touch are likely to grow in demand. One challenge facing engineers is the difficulty in making the kind of cost-effective, highly sensitive sensor necessary for applications such as detecting subtle pulses, operating robotic limbs, and creating ultrahigh-resolution scales. However, a team of researchers has developed a sensor capable of performing all of those tasks.

Newswise:Video Embedded patch-detects-muscle-movement-through-skin-w-nanomagnets
VIDEO
Released: 27-Jun-2023 6:30 PM EDT
This patch uses nanomagnets to detect muscle movement through the skin
Cell Press

Using nanomagnets composites and conductive yarn, scientists have invented a smart textile that can sense and measure body movements—from muscles flexing to veins pulsing.

   
Released: 26-Jun-2023 12:00 PM EDT
Factors affecting osteogenesis and chondrogenic differentiation of mesenchymal stem cells in osteoarthritis
World Journal of Stem Cells

Osteoarthritis (OA) is a common degenerative joint disease that often involves progressive cartilage degeneration and bone destruction of subchondral bone. At present, clinical treatment is mainly for pain relief, and there are no effective

Released: 26-Jun-2023 12:00 PM EDT
Culture and identification of neonatal rat brain-derived neural stem cells
World Journal of Stem Cells

BACKGROUNDTiming of passaging, passage number, passaging approaches and methods for cell identification are critical factors influencing the quality of neural stem cells (NSCs) culture. How to effectively culture and identify NSCs is a cont

Released: 26-Jun-2023 12:00 PM EDT
Synergism of calycosin and bone marrow-derived mesenchymal stem cells to combat podocyte apoptosis to alleviate adriamycin-induced focal segmental glomerulosclerosis
World Journal of Stem Cells

BACKGROUNDBone marrow-derived mesenchymal stem cells (MSCs) show podocyte-protective effects in chronic kidney disease. Calycosin (CA), a phytoestrogen, is isolated from Astragalus membranaceus with a kidney-tonifying effect. CA preconditio

Released: 26-Jun-2023 12:00 PM EDT
Potential regulatory effects of stem cell exosomes on inflammatory response in ischemic stroke treatment
World Journal of Stem Cells

The high incidence and disability rates of stroke pose a heavy burden on society. Inflammation is a significant pathological reaction that occurs after an ischemic stroke. Currently, therapeutic methods, except for intravenous thrombolysis

Released: 26-Jun-2023 12:00 PM EDT
Current overview of induced pluripotent stem cell-based blood-brain barrier-on-a-chip
World Journal of Stem Cells

BACKGROUNDInduced pluripotent stem cells (iPSCs) show great ability to differentiate into any tissue, making them attractive candidates for pathophysiological investigations. The rise of organ-on-a-chip technology in the past century has in

Released: 26-Jun-2023 12:00 PM EDT
Clinical relevance of stem cells in lung cancer
World Journal of Stem Cells

Lung cancer is the major cause of cancer-related deaths worldwide, it has one of the lowest 5-year survival rate, mainly because it is diagnosed in the late stage of the disease. Lung cancer is classified into two groups, small cell lung ca

Released: 26-Jun-2023 12:00 PM EDT
Advances of nanotechnology applied to cancer stem cells
World Journal of Stem Cells

Cancer stem cells (CSCs) are a small proportion of the cells that exist in cancer tissues. They are considered to be the culprit of tumor genesis, development, drug resistance, metastasis and recurrence because of their self-renewal, prolif

Released: 26-Jun-2023 12:00 PM EDT
Adipokines regulate mesenchymal stem cell osteogenic differentiation
World Journal of Stem Cells

Mesenchymal stem cells (MSCs) can differentiate into various tissue cell types including bone, adipose, cartilage, and muscle. Among those, osteogenic differentiation of MSCs has been widely explored in many bone tissue engineering studies.

Released: 26-Jun-2023 12:00 PM EDT
Single cell RNA sequencing reveals mesenchymal heterogeneity and critical functions of Cd271 in tooth development
World Journal of Stem Cells

BACKGROUNDAccumulating evidence suggests that the maxillary process, to which cranial crest cells migrate, is essential to tooth development. Emerging studies indicate that Cd271 plays an essential role in odontogenesis. However, the underl

Released: 26-Jun-2023 12:00 PM EDT
Neural lineage differentiation of human pluripotent stem cells: Advances in disease modeling
World Journal of Stem Cells

Brain diseases affect 1 in 6 people worldwide. These diseases range from acute neurological conditions such as stroke to chronic neurodegenerative disorders such as Alzheimer’s disease. Recent advancements in tissue-engineered brain disea

Newswise: Bias from pulse oximeters remains even if corrected by race, study finds
Released: 26-Jun-2023 10:00 AM EDT
Bias from pulse oximeters remains even if corrected by race, study finds
Washington University in St. Louis

Pulse oximeters were a critical part of life-saving care during the COVID-19 pandemic, shaping treatment by measuring oxygen levels in the blood. The devices, which became common in the 1980s, have long shaped protocols for detecting hypoxemia, low blood oxygenation that can lead to organ failure and death.

   
Released: 22-Jun-2023 3:05 PM EDT
Rensselaer Researcher Uses Pressure To Understand RNA Dynamics
Rensselaer Polytechnic Institute (RPI)

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, is dedicated to understanding the conformational landscapes of biomolecules and how they modulate cell function.

Newswise: Bringing the Power Of
Released: 22-Jun-2023 11:45 AM EDT
Bringing the Power Of "Multiplex" Imaging to Clinical Pathology
Ludwig Cancer Research

Researchers at the Ludwig Center at Harvard have developed a platform technology for imaging that enables integration of the methods of microscopic analysis long employed in pathology laboratories with the visualization of multiple molecular markers in individual cells that is now rapidly advancing in research labs.

   
Newswise: Loyola Medicine Improves Health Equity by Increasing Access to 
Kidney Transplants for Patients with Obesity
Released: 20-Jun-2023 6:00 PM EDT
Loyola Medicine Improves Health Equity by Increasing Access to Kidney Transplants for Patients with Obesity
Loyola Medicine

Loyola Medicine's advanced robotic surgery program makes it one of the few hospitals in the country to offer kidney transplantation to patients with obesity.

Newswise:Video Embedded silicon-nose-small-sensor-smells-incipient-seizures
VIDEO
Released: 20-Jun-2023 10:05 AM EDT
Silicon nose: Small sensor "smells" incipient seizures
Sandia National Laboratories

Sandia National Laboratories and research partner Know Biological have developed a miniaturized sensor system that can detect the specific gases released from the skin of people with epilepsy before a seizure.

Released: 16-Jun-2023 7:45 PM EDT
New imaging technique is no last resort
University of Tokyo

There are various ways to image biological samples on a microscopic level, and each has its own pros and cons. For the first time, a team of researchers, including those from the University of Tokyo, has combined aspects from two of the leading imaging techniques to craft a new method of imaging and analyzing biological samples.

Newswise: Chronic wound healing using glass
Released: 15-Jun-2023 2:35 PM EDT
Chronic wound healing using glass
University of Birmingham

Researchers at the University of Birmingham have demonstrated that silver retains antimicrobial activity for longer when it is impregnated into ‘bioactive glass’, and shown for the first time how this promising combination delivers more long-lasting antimicrobial wound protection than conventional alternatives.

Newswise:Video Embedded a-spy-in-the-belly
VIDEO
Released: 15-Jun-2023 3:05 AM EDT
A "spy" in the belly
Empa, Swiss Federal Laboratories for Materials Science and Technology

To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers at Empa and ETH Zurich have developed a patch with a sensor function. The polymer patch warns before the occurence of dangerous leaks on sutures in the gastrointestinal tract take hold, while closes the areas on its own. A new material now enables a fast, easy and non-invasive leak diagnosis. The team recently published their findings in the journal Advanced Science.

   
Released: 14-Jun-2023 12:45 PM EDT
UK Army & NHSBT Dry Plasma Development Contract Awarded to Velico
Velico Medical, Inc

An innovative project to rapidly deliver blood and plasma to injured soldiers is set to save lives in warzones. The UK Ministry of Defence's Blood Far Forward programme aims to deliver blood and plasma within 30 minutes of injury to soldiers in active warzones.

   
Released: 14-Jun-2023 12:40 PM EDT
Specialty drugs accounted for most new product launches in the past decade. Why do we know so little about how clinical studies influence their diffusion?
American Marketing Association (AMA)

Researchers from McGill University and Ontario Tech University published a new Journal of Marketing article that examines the drivers of specialty drug diffusion.

   
Newswise: Former Philadelphia City Solicitor Sozi Tulante Appointed to Wistar Institute Board of Trustees
Released: 14-Jun-2023 10:05 AM EDT
Former Philadelphia City Solicitor Sozi Tulante Appointed to Wistar Institute Board of Trustees
Wistar Institute

Wistar is pleased to welcome Sozi Tulante to its Board of Trustees. He is currently General Counsel of Form Energy, a Massachusetts-based energy storage technology and manufacturing company.

Newswise: Moffitt Cancer Center Taps W. Gregory Sawyer, Ph.D., as Inaugural Chair of the Department of Bioengineering
Released: 14-Jun-2023 7:05 AM EDT
Moffitt Cancer Center Taps W. Gregory Sawyer, Ph.D., as Inaugural Chair of the Department of Bioengineering
Moffitt Cancer Center

Moffitt Cancer Center has launched the Department of Bioengineering. The new academic research department will be housed within the Division of Basic Science and led by W. Gregory Sawyer, Ph.D. Bioengineering integrates the disciplines of engineering and cancer biology.

Newswise: Bioprinting personalized tissues and organs within the body: A breakthrough in regenerative medicine
Released: 13-Jun-2023 12:45 PM EDT
Bioprinting personalized tissues and organs within the body: A breakthrough in regenerative medicine
Institute of Physics (IOP) Publishing

In situ bioprinting, which involves 3D printing biocompatible structures and tissues directly within the body, has seen steady progress over the past few years.

Newswise: Researchers Demonstrate First Precision Gene Editing in Miscanthus
Released: 12-Jun-2023 4:00 PM EDT
Researchers Demonstrate First Precision Gene Editing in Miscanthus
Department of Energy, Office of Science

Miscanthus thrives on marginal lands with limited fertilization and tolerates drought and cool temperatures, making it an ideal bioenergy candidate. Previous efforts to genetically improve miscanthus focused on introducing external genes at random places in the plant’s genomes. This research developed gene-editing procedures using CRISPR/Cas9 that will allow scientists to selectively target existing genes to knock out their function and introduce new genes into precise locations.

Released: 12-Jun-2023 9:35 AM EDT
The American Society of Nephrology and HHS Announce Winners of $9.2 Million Artificial Kidney Prize Phase 2 at Kidneyx Summit
American Society of Nephrology (ASN)

Today, the Kidney Innovation Accelerator (KidneyX), a public private partnership between the American Society of Nephrology (ASN) and the US Department of Health and Human Services (HHS) announced the eight winners of the Artificial Kidney Prize Phase 2 at the KidneyX Summit in Washington, DC. The competition recognized participants’ innovative approaches to developing a bioartificial kidney and was divided into two tracks with two Track 1 participants each receiving $1,600,000, and six Track 2 participants each receiving $1,000,000.

Released: 9-Jun-2023 7:10 PM EDT
New high-tech helmets may protect American football players from debilitating concussions
Frontiers

Millions of people in the US are concussed every year playing sports. Players of games like American football are at particularly high risk for injuries that can have devastating long-term consequences. Stanford University scientists working with the company Savior Brain have now designed one potential way of protecting players: a helmet containing liquid shock absorbers that could reduce the impact of blows to the head by a third.

Released: 9-Jun-2023 1:35 PM EDT
Wireless device enables catheter-free bladder pressure monitoring
Wolters Kluwer Health: Lippincott

A wireless device called the UroMonitor enables accurate, noninvasive monitoring of bladder pressure in patients with overactive bladder, reports a pilot study in the July issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 7-Jun-2023 3:15 PM EDT
Looking deeper with adaptive six-dimensional nanoscopy
Washington University in St. Louis

Matthew Lew, an associate professor of electrical and systems engineering at the McKelvey School of Engineering at Washington University in St. Louis, has received a five-year $2 million Maximizing Investigators’ Research Award (MIRA) from the National Institutes of Health (NIH) to support his ongoing work to improve microscopic imaging techniques.

Newswise: Combining bioprinting techniques to pursue functional blood vessels
Released: 7-Jun-2023 1:05 PM EDT
Combining bioprinting techniques to pursue functional blood vessels
University Medical Center Utrecht

In this project volumetric bioprinting was for the first time successfully combined with melt electrowriting.

Released: 7-Jun-2023 7:05 AM EDT
IIT Kanpur Pioneers Ground-Breaking Gene Therapy Technology for Hereditary Eye Diseases
Indian Institute of Technology Kanpur

IIT Kanpur has licensed a pioneering technology to Reliance Life Sciences Pvt. Ltd. that has the potential to revolutionize the field of gene therapy, especially for many genetic eye diseases, making it the first time that a gene therapy related technology has been developed and transferred from an academic institution to a company in India.

Newswise: Programmable 3D printed wound dressing could improve treatment for burn, cancer patients
Released: 6-Jun-2023 2:55 PM EDT
Programmable 3D printed wound dressing could improve treatment for burn, cancer patients
University of Waterloo

One of the challenges in treating burn victims is the frequency of dressing changes, which can be extremely painful.

Newswise: Cancer cells rev up synthesis, compared with neighbors
Released: 1-Jun-2023 3:35 PM EDT
Cancer cells rev up synthesis, compared with neighbors
Washington University in St. Louis

Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets. Researchers from Washington University in St. Louis have developed a technology to study tumor growth in another dimension — literally. The scientists established a new method to watch what nutrients are used at which rates spatially throughout a tissue.

Released: 1-Jun-2023 10:40 AM EDT
Tiny Video Capsule Shows Promise as an Alternative to Endoscopy
George Washington University

While ingestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians. They moved passively, driven only by gravity and the natural movement of the body.

Newswise: Antibiotics crisis: nanoparticles as therapy guide
Released: 1-Jun-2023 2:05 AM EDT
Antibiotics crisis: nanoparticles as therapy guide
Empa, Swiss Federal Laboratories for Materials Science and Technology

In the case of blood poisoning, the bacteria in the blood must be identified as fast as possible so that a life-saving therapy can be started. Empa researchers have now developed "sepsis sensors" with magnetic nanoparticles that detect bacterial pathogens within a short period of time and identify suitable candidates for antibiotic therapies.

Newswise: Announcing the SLAS Technology Editor’s Top 10 for 2023
Released: 31-May-2023 8:00 AM EDT
Announcing the SLAS Technology Editor’s Top 10 for 2023
SLAS

The SLAS Technology Editor’s Top 10 for 2023 highlights technologies that address a broad range of unmet needs in both the laboratory and the clinic.

   
Newswise: Ankle exosuit for community walking aims to give post-stroke wearers more independence
Released: 30-May-2023 7:00 PM EDT
Ankle exosuit for community walking aims to give post-stroke wearers more independence
Harvard John A. Paulson School Of Engineering And Applied Sciences

Every 40 seconds, someone in the United States has a stroke. According to the U.S. Centers for Disease Control and Prevention, that totals about 795,000 strokes each year. More than 80 percent of stroke survivors experience gait challenges, often relating to a loss of control over ankle movement. As survivors progress into the chronic stage of stroke, most continue to walk slower and less efficiently.

Released: 30-May-2023 6:00 PM EDT
New DNA testing technology shows majority of wild dingoes are pure, not hybrids
University of New South Wales

Wild dingo populations have less dog lineage, with a significantly greater proportion of pure dingoes than previously thought, according to new research, challenging the view that pure dingoes are on the decline due to crossbreeding.

Released: 26-May-2023 12:00 PM EDT
Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical use
World Journal of Stem Cells

Mesenchymal stromal/stem cells (MSCs) have shown significant therapeutic potential, and have therefore been extensively investigated in preclinical studies of regenerative medicine. However, while MSCs have been shown to be safe as a cellul

Released: 26-May-2023 12:00 PM EDT
Modulation of stem cell fate in intestinal homeostasis, injury and repair
World Journal of Stem Cells

The mammalian intestinal epithelium constitutes the largest barrier against the external environment and makes flexible responses to various types of stimuli. Epithelial cells are fast-renewed to counteract constant damage and disrupted bar



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