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Drug Resistance

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Medicine

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C. Difficile, CDI, C, Vancomycin, metronidazole, hospital-acquired infection

Routinely Prescribed Antibiotic May Not Be Best for Treating Severe C. diff Infections

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Over the past two decades there has been a sharp rise in the number and severity of infections caused by the bacteria Clostridium difficile often shortened to C. diff now the most common hospital acquired infection in the United States. But a new study suggests that the most routinely prescribed antibiotic is not the best treatment for severe cases. Scientists at the VA Salt Lake City Health Care System and University of Utah School of Medicine report that patients with a severe C. diff infection (CDI) were less likely to die when treated with the antibiotic vancomycin compared to the standard treatment of metronidazole.

Medicine

Channels:

Bacteria, E. Coli Bacteria, E. Coli, Superbugs, antiobiotic resistance, Diagnostic Testing, Point Of Care Diagnostics, Point Of Care Testing, Antibiotics, Sepsis, Drug Resistance

Faster Way of Detecting Bacteria Could Save Your Life

A Michigan State University researcher has developed a faster way to detect the bacteria causing patients to become sick, giving physicians a better chance at saving their lives.

Medicine

Channels:

Cancer Research, Breast Cancer, Head And Neck Cancer, Otolaryngology, Cancer, cancer cell biology, dormant cancer cells, Dormancy, Hypoxia, Chemotherapy, Cancer Drug, cancer drug resistance, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Tumor, cancer tumor, Disease

Mount Sinai Researchers Discover How Primary Tumors Can Program Cancer Cells That Spread to Become Dormant and Resist Cancer Treatment

Findings could transform cancer drug development and patient care

Medicine

Channels:

Tau Tangles, tau, Alzheimer Disease & Associated Disorders, Tauopathy, Oligonucleotides

Drug Compound Halts Alzheimer’s-Related Damage in Mice

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In some people, the brain protein tau collects into toxic tangles that damage brain cells and contribute to diseases such as Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have found a drug that can lower tau levels and prevent some neurological damage.

Science

Channels:

Malaria, Drug Resistance, Malaria Drug Resistance

Texas Biomed Scientist Receives 5-Year, $4.6 Million Merit Award From NIH for Malaria Research

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Dr. Timothy Anderson, Scientist in the Department of Genetics at Texas Biomedical Research Institute, received a five-year, $4.6 million MERIT Award from the National Institutes of Health.

Medicine

Channels:

Tuberculosis, TB, Tb Drugs, TB infection, Parabolic Response Surface Platform, Drug regimen, Drug Resistance, Drug Resistant Tuberculosis

New Tuberculosis Therapy Could Be More Potent Than Current Treatments

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Researchers have devised a potential drug regimen for tuberculosis that could cut the treatment time by up to 75 percent, while simultaneously reducing the risk that patients could develop drug-resistant TB.

Medicine

Channels:

triple negative breast cancer, Drug Resistance, trametinib

Researchers Unlock Mechanism of Drug Resistance in Aggressive Breast Cancer

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In the journal Cancer Discovery, UNC Lineberger Comprehensive Cancer Center researchers and colleagues report findings of how triple negative breast cancer cells are able to bypass treatment with trametinib, a U.S. Food and Drug Administration-approved drug that belongs to a class of commonly used anti-cancer drugs called kinase inhibitors. The researchers also reported findings from laboratory models of breast cancer testing a potential treatment approach that could prevent the onset of resistance.

Medicine

Channels:

Duke Health, Infections Diseases, Mrsa Infections, UV disinfection, UVC , Acinetobacter, C Difficile, vancomycin-resistant Enterococcus faecium, drug-resistant bacteria, drug-resistant organisms, drug-resistant bacterial pathogens, Hospital Safety, Hospital Infection Rates, Infection Control, CDC, CDC Prevention Epicenters Program, Niaid, National Center f

UV Light Can Aid Hospitals’ Fight to Wipe Out Drug-Resistant Superbugs

A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.

Medicine

Channels:

antibiotic resisistance, Infection Control

Creighton Expert Available to Talk About Antibiotic Resistant Infections and Antibiotics

Medicine

Channels:

C Diff, Stem Cell Transplant, Cancer, Antibiotic, Antibiotic Stewardship , Antibiotic Resistance

Walking the Tightrope

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Antibiotic use represents a special challenge, in which too much of a good thing can be dangerous to public health as a whole. The fight against a common, costly, hospital-acquired infection known as Clostridium difficile, or C. diff offers an illuminating case study in the area of so-called antibiotic stewardship.







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