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Article ID: 695986

Newly-Approved Therapy Provides Improved Quality of Life for Patients with Advanced Metastatic Midgut Neuroendocrine Tumors

Moffitt Cancer Center

Midgut neuroendocrine tumors are a rare type of cancer that develops in the small intestine and colon. Roughly 12,000 people are diagnosed with this disease each year. In January, the United Stated Food and Drug Administration approved Lutathera, a first-of-its-kind peptide receptor radionuclide therapy. The injection consists of a somatostatin analog combined with a radioactive isotope that directly targets neuroendocrine tumor cells.

Released:
12-Jun-2018 9:25 AM EDT
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    12-Jun-2018 8:00 AM EDT

Article ID: 695737

CureWorks Collaborative Launches to Accelerate Development of Immunotherapy Treatments for Childhood Cancers, Increase Access to Clinical Trials

CureWorks

Seattle Children’s, with participating members Children’s National Health System, BC Children’s Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children’s hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer. CureWorks focuses on expanding immunotherapy trials and patient access around the world, as well as sharing data and collective expertise to advance novel cell therapies.

Released:
7-Jun-2018 8:00 AM EDT
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  • Embargo expired:
    11-Jun-2018 4:00 PM EDT

Article ID: 695948

PARP Inhibitor Improves Overall Response Rates in Small Cell Lung Cancer Patients

University of Texas M. D. Anderson Cancer Center

In a randomized, Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, adding the PARP inhibitor veliparib to a standard chemotherapy agent improved overall response rates (ORR) in patients with small cell lung cancer (SCLC). Researchers also identified a select group of patients – those whose tumors expressed SLFN11— who also saw a progression-free survival (PFS) and overall survival (OS) benefit, suggesting a promising biomarker for the PARP-inhibitor sensitivity in SCLC.

Released:
11-Jun-2018 3:20 PM EDT
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Article ID: 695927

New Target for Treating Heart Failure Identified by Penn Medicine Researchers

Perelman School of Medicine at the University of Pennsylvania

Changes in cellular struts called microtubules can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.

Released:
11-Jun-2018 12:05 PM EDT
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Article ID: 695914

IU Scientists Watch Bacteria 'Harpoon' DNA to Speed Their Evolution

Indiana University

Researchers at Indiana University have made the first direct observation of how bacteria use appendages thousands of times thinner than a human hair to absorb DNA in the environment. The work could help advance efforts stop antibiotic resistant bacteria.

Released:
11-Jun-2018 11:05 AM EDT
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    11-Jun-2018 11:00 AM EDT

Article ID: 695886

MD Anderson Therapeutics Discovery team identifies and advances a drug that targets metabolic vulnerability and impairs cancer cell growth and survival

University of Texas M. D. Anderson Cancer Center

A drug discovered and advanced by The University of Texas MD Anderson Cancer Center’s Institute for Applied Cancer Science (IACS) and the Center for Co-Clinical Trials (CCCT) inhibits a vital metabolic process required for cancer cells’ growth and survival.

Released:
8-Jun-2018 6:05 PM EDT
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Article ID: 695885

UT Southwestern investigators identify missing link in kidney cancer prognosis

UT Southwestern Medical Center

Normal cells located next to kidney cancer cells provide new clues about prognosis and survival rates, researchers from UT Southwestern Medical Center’s Kidney Cancer Program report.

Released:
8-Jun-2018 5:05 PM EDT
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Article ID: 695567

A Change in Bacteria’s Genetic Code Holds Promise of Longer-Lasting Drugs

University of Texas at Austin (UT Austin)

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience

Released:
8-Jun-2018 12:05 PM EDT
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Article ID: 695830

FSU Expert Available to Discuss NASA Mars Discovery

Florida State University

Released:
8-Jun-2018 8:05 AM EDT
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Article ID: 695823

Mars Researcher Available to Discuss NASA's Curiosity Rover Discovering Methane, Organic Material on Mars

Northern Arizona University

Mark Salvatore, who studied the surface of the Red Planet, also is part of a team that collaborates with scientists, engineers and NASA's rover operations to guide the Curiosity around Mars.

Released:
7-Jun-2018 7:05 PM EDT
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