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Medicine

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george washington university school of medicine and health sciences, HIV, Research, T Cell, Microbiology And Immunology, Journal of Clinical Investigation, kick and kill

GW Researchers Find Latent HIV Reservoirs Inherently Resistant to Elimination by CD8+ T-cells

A research team at GW School of Medicine and Health Sciences found that latent HIV reservoirs exhibit resistance to elimination by CD8+ T-cells of people living with the virus.

Medicine

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AIDS, HIV, Hiv Testing, Ukraine, Social Networks, Risk networks, NDRI, CDUHR, Center for Drug Use and HIV Research

Using Social and Risk Networks Helps Identify People Undiagnosed with HIV

Conducting HIV testing among the social and risk networks of those recently diagnosed with HIV helps identify undiagnosed cases of HIV at significantly higher rates and at a lower cost than other testing approaches, finds a new study conducted in Ukraine by an international research team.

Medicine

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Cystic Fibrosis, Pulmonology

Cystic Fibrosis Bacterial Burden Begins During First Years of Life

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CF researchers have now shown that the lungs’ bacterial population changes in the first few years of life as respiratory infections and inflammation set in. This research offers a way to predict the onset of lung disease and suggests a larger role for preventive therapies, such as hypertonic saline.

Medicine

Science

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Flu Shot, Influenza, Virus, Infectious Disease, Genetics, Interferons, Vaccines

Flu Vaccine Could Get a Much-Needed Boost

More than 700,000 Americans were hospitalized due to illnesses associated with the seasonal flu during the 2014–15 flu season, according to federal estimates. A radical new approach to vaccine development at UCLA may help lower that figure for future flu seasons.

Medicine

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GW School of Medicine and Health Sciences, Baylor College Of Medicine, Schistosomiasis, Infectious Disease, Tropical Medicine, Global Medicine, Parasitology, Parasites, Vaccine, Clinical Trial

Schistosoma Vaccine to Enter Phase Ib Clinical Trial

Researchers at Baylor College of Medicine, in collaboration with a team of researchers at the George Washington University and the René Rachou Institute, have received funding from the National Institutes of Health for a Phase Ib clinical trial for a Schistosomiasis vaccine in an endemic area of Brazil.

Medicine

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Case Western Reserve University School Of Medicine, University Hospitals Cleveland Medical Center, Jonathan Stamler, Enzymes, Cell Function, Nitric Oxide, NO, SNOs, Heart Failure, Cancer, Asthma, Infection, NO synthases, S-nitrosylation, Therapeutic Targets, drug developers, Memory, Molecular Cell

Researchers Discover New Enzymes Central to Cell Function

Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular Cell suggests supplementing nitric oxide—NO—is only the first step. Researchers have discovered previously unknown enzymes in the body that convert NO into “stopgap” molecules—SNOs—that then modulate proteins. The newly discovered enzymes help NO have diverse roles in cells. They may also be prime therapeutic targets to treat a range of diseases.

Medicine

Science

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The Wistar Institute Awarded More Than $1.4 Million to Create a Malaria Vaccine Through Synthetic DNA-Based Technology

Wistar is pleased to announce it has been awarded a $1,494,972 grant by the Bill & Melinda Gates Foundation to advance a DNA-based vaccine candidate for protection against malarial infection utilizing a synthetic DNA platform created in the lab of David B. Weiner, Ph.D., executive vice president, director of the Vaccine & Immunotherapy Center at The Wistar Institute and the W.W. Smith Charitable Trust Professor in Cancer Research.

Medicine

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Arthroplasty, Joint Replacement, Infection, next generation sequencing, periprosthetic joint infection, Antibiotics

Novel Method of Isolating Infecting Organisms After Joint Replacement

Next-generation Genomic Sequencing could help identify infecting organisms and guide treatment for patients with joint-replacement infection

Medicine

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HIV, AIDS, CURE, Antibodies, Treatment, Prevention

Multivalent Antibodies Show Effectiveness for HIV Prevention and Promise for Treatment and Cure

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Recent studies testing multivalent combinations of three broadly neutralizing antibodies, or bnAbs, have yielded promising results in animal models of HIV prevention. Two investigators at the University of North Carolina at Chapel Hill describe the potential of bnAbs to inform HIV prevention, treatment and cure strategies in a recent article in the New Journal of Medicine.

Medicine

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Influenza, H3N2, flu, flu and children, Influenza A, Influenza B

Flu Season: How to Stay Healthy

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A Rutgers medical expert explains why this year’s flu season is so fierce and how you can protect yourself







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