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Medicine

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Behavioral Economics, nudges, physician behavior, Prescribing Habits, Prescribing Patterns, electronic medical record (EMR), Penn Medicine, JAMA Internal Medicine

Changing Default Prescription Settings in Electronic Medical Records Increased Prescribing Rates of Generic Drugs, Penn Medicine Study Finds

A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania, found that a simple change to prescription default options in electronic medical records immediately increased generic prescribing rates from 75 percent to 98 percent.

Medicine

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pregnancy and health, Birth Defects

UCLA Study Finds No Evidence Linking Anti-Nausea Drug to Birth Defects

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A new study by a UCLA researcher has found no evidence to link the anti-nausea drug to an increased risk of birth defects. In fact, women with the condition who took Zofran reported fewer miscarriages and pregnancy terminations and higher live birth rates than women with extreme morning sickness who did not take the drug

Medicine

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Sanford Burnham Prebys Medical Discovery Institute, Ruoslahti, University of Manchester, U.K, March Of Dimes, Prenatal, Preeclampsia, Drug Delivery, Reproductive Health, Life Science, Nanotechnology, Pregnancy, Womens Health, health science, Biotechnology, Pharmaceutical Research

Researchers Find a Way to Deliver Drugs to the Placenta to Support Healthier Pregnancies

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Discovery provides proof of principle for safe, targeted delivery of drugs to the placenta to improve pregnancy outcomes

Medicine

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Cell Biology, Pharmaceucticals

Understanding Lock for Cellular Trap Door May Lead to Better Disease Treatment

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A team of researchers who two years ago announced a “Trojan horse” method of entering a cell without harming it have now found, in effect, the lock to the cellular “trap door.”

Medicine

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Atrial Fibrillation, atrial fibrillations, atrial fibrillation (AF), AF, Warfarin, Arrythmia, arrythmias, heart beat, Heart Abnormalities, Heart Disease, heart disorders, intermountain medical center, Heart Rhythm, heart rhythm 2016, Heart Rhythm Society , Stroke, Heart Attack, Clots, intermountain healthcare, UTAH, San Francisco, Heart Research

New Study Finds Atrial Fibrillation Patients Treated With Warfarin Have Higher Rates of Dementia

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Study of more than 10,000 patients treated long term with the blood thinner, warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients

Medicine

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Gastroenterology, Inflamamatory Bowel Disease (Ibd), Ulcerative Colitis, Pharmaceutical Science

Study Shows Ozanimod as Effective in Treating Ulcerative Colitis

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Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

Medicine

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First Structural Views of the NMDA Receptor in Action Will Aid Drug Development

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Structural biologists at Cold Spring Harbor Laboratory (CSHL) and Janelia Research Campus/HHMI, have obtained snapshots of the activation of an important type of brain-cell receptor. Dysfunction of the receptor has been implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, seizure, schizophrenia, autism, and injuries related to stroke.

Medicine

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What’s Behind the Heartbreaking Risk of Anti-Inflammatory Drugs

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Researchers have known for more than a decade that the risk of heart disease and stroke increases when people take pain relievers like ibuprofen and other non-steroidal anti-inflammatory drugs, or NSAIDs. Now, scientists from the University of California, Davis, have uncovered some of the reasons why these drugs can harm heart tissue.

Medicine

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Carbapenem-resistant Enterobacteriaceae , Bacteria, microbioloby, CRE carbapenem-resistant Enterobacteriaceae , CRE, Antibiotic Resistance, Pathology

Screening Method Uncovers Drugs That May Combat Deadly Antibiotic-Resistant Bacteria

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In recent years, hospitals have reported dramatic increases in the number of cases of the highly contagious, difficult-to-treat, and often deadly antibiotic-resistant bacteria carbapenem-resistant Enterobacteriaceae (CRE). Now, investigators at Beth Israel Deaconess Medical Center (BIDMC) have developed a promising method of identifying new antimicrobials that target these organisms. The research is published in April issue of the journal ASSAY and Drug Development Technologies.

Medicine

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Study Shows How Different People Respond to Aspirin — an Important Cardioprotective Drug

Researchers have learned new information about how different people respond to aspirin, a globally prescribed drug in cardioprotection. The team identified more than 5,600 lipids in blood platelets and gained new insights into how these cells respond to aspirin.







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