A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body’s first response to infection, UT Southwestern researchers report.
Motivated by a desire to better understand the molecular circuitry underlying neuroblastoma and limitations of current methods for predicting disease progression and outcome, researchers from the Kulesa Lab at the Stowers Institute for Medical Research and collaborators at the University of Michigan and Oxford University set out to construct a logic-based model incorporating information about developmental signaling pathways implicated in the disease.
The survival mechanisms of polar fish have led scientists at the University of Warwick to develop of a revolutionary approach to ‘freeze’ bacteria.
An extremely fast “electron camera” at the Department of Energy’s SLAC National Accelerator Laboratory has produced the most detailed atomic movie of the decisive point where molecules hit by light can either stay intact or break apart. The results could lead to a better understanding of how molecules respond to light in processes that are crucial for life, like photosynthesis and vision, or that are potentially harmful, such as DNA damage from ultraviolet light.
Florida State scientists have devised a new strategy for synthesizing notoriously difficult carbocyclic 5-8-5 fused ring systems, a molecular structure with broad therapeutic potential.
Dr. Angela Lueking, a professor of energy and mineral engineering and chemical engineering at Pennsylvania State University and a recent program director at the National Science Foundation, is joining Missouri S&T as associate dean of research in the College of Engineering and Computing starting Aug. 1.
St. Louis, May 14, 2018 BacterioScan, Inc. today announced that the U.S. Food and Drug Administration (FDA) has issued a 510(k) Premarket Notification clearance for its 216Dx Urinary Tract Infection (UTI) detection system. The BacterioScan 216Dx system is a rapid automated diagnostic system for the detection of bacterial UTIs, one of the most common types of infection.
The American Society for Biochemistry and Molecular Biology this week named a dozen scientists the winners of its annual awards. The winners were nominated by colleagues and other leaders in their fields for making significant contributions to biochemistry and molecular biology and the training of emerging scientists.
A study by a team that includes Amrita Banerjee, assistant professor of pharmaceutical sciences at North Dakota State University, Fargo, shows promise in administering insulin in pill form. Banerjee is listed as first author in the study published in the Proceedings of the National Academy of Sciences.
Scientists at Missouri University of Science and Technology are drawing inspiration from toy building blocks to create fixed molecular units used to accelerate the material discovery process known as rational design. They’ll use these “molecular blocks” to discover highly ionic conductive materials that could be used to make today’s much sought after all-solid-state lithium batteries.
The research offers another approach for tackling diseases that have been considered "undruggable," including amyotrophic lateral sclerosis (ALS), muscular dystrophy, cystic fibrosis and certain cancers.
AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce that the impact factor of its journal, Clinical Chemistry, has risen to 8.636 in the 2017 Thomson Reuters Journal Citation Reports. This impact factor places Clinical Chemistry in the top 2.5% of 12,271 ranked academic journals and speaks to the significant influence of the science it publishes on laboratory medicine and patient care.
Liquid water sustains life on earth, but its physical properties remain mysterious among scientific researchers. Recently, a team of Swiss researchers used existing THz spectroscopy techniques to measure liquid water’s hydrogen bonding. Future efforts with this technique could one day help explain water’s peculiar properties. The team reports their findings in The Journal of Chemical Physics.
To improve water treatment, researchers use modeling to understand how chemical byproducts form during the advanced oxidation process.
The Blavatnik Family Foundation and the New York Academy of Sciences today announced the 2018 Laureates of the Blavatnik National Awards for Young Scientists, who will each receive $250,000: the largest unrestricted scientific prize offered to America’s most promising faculty-level scientific researchers 42 years of age and younger.
Bioelectrochemical systems combine the best of both worlds – microbial cells with inorganic materials – to make fuels and other energy-rich chemicals with unrivaled efficiency. Yet technical difficulties have kept them impractical anywhere but in a lab. Now researchers at Lawrence Berkeley National Laboratory (Berkeley Lab) have developed a novel nanoscale membrane that could address these issues and pave the way for commercial scale-up.
StealthCo, Inc., an Oak Ridge, Tenn.-based firm doing business as Stealth Mark, has exclusively licensed an invisible micro-taggant from Oak Ridge National Laboratory. The anticounterfeiting technology features a novel materials coding system that uses an infrared marker for identification.
A Mississippi State faculty member and structural biophysicist is the recipient of a $1.8 million grant from the National Institutes of Health to study how bacterial proteins attach to surfaces and impact public health.
A new study provides a platform for predicting how microbial gut communities work and represents a first step toward understanding how to manipulate the properties of the gut ecosystem. This could allow scientists to, for example, design a probiotic that persists in the gut or tailor a diet to positively influence human health.
Promising experimental cancer chemotherapy drugs may help knock out another life-threatening disease: tuberculosis (TB).
The microbiome may harbor a gene for drug resistance
University of North Carolina School of Medicine researchers have discovered that a protein called Spt6 facilitates RNA degradation so that cells have just the right amount of RNA for the creation of proteins, a key component to human health and the avoidance of disease.
In a paper published in Nature, a team led by Uli Wiesner, the Spencer T. Olin Professor of Engineering in the Department of Materials Science and Engineering at Cornell University, reports discovery of 10-nanometer, individual, self-assembled dodecahedral structures – 12-sided silica cages that could have applications in mesoscale material assembly, as well as medical diagnosis and therapeutics.
• Chameleons change color by controlling the spacing among nanocrystals on their skin • Northwestern’s nanolaser changes color similarly — by controlling the spacing among metal nanoparticles • By stretching and releasing an elastic substrate, the nanoparticles move further apart or closer together to control color
Researchers at Missouri University of Science and Technology have discovered a new way to harness the potential of a type of spontaneously oxidized MXene thin films, to create nanocomposites that could sense both light and the environment. Previously, such spontaneous oxidation was considered detrimental because it degrades the MXene structure. The research is published in the June 2018 issue of ACS Nano, one of Google Scholar’s top-rated, peer-reviewed scientific journals.
Aim Lab is making the automation of sample tube processing more accessible with their PathFinder 350D Decapper/Sorter and PathFinder 350A Archiver compact robotic workstations.
Plants can be genetically rewired to resist the devastating effects of disease – significantly reducing crop waste worldwide – according to new research into synthetic biology by the University of Warwick.Led by Professor Declan Bates from the Warwick Integrative Synthetic Biology Centre (WISB) and Professor Katherine Denby from the University of York, who is also an Associate member of WISB, researchers have developed a genetic control system that would enable plants to strengthen their defence response against deadly pathogens – so they could remain healthy and productive.
Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized ‘miniecosystems’ to quickly see if a molecule can function as a potential therapeutic.
DRG International, a leading international medical diagnostic company, will showcase its DRG® Aldosterone ELISA Kit at the 2018 AACC Conference in Chicago, Illinois from July 29 – August 2. The DRG International Aldosterone ELISA is for measurement of Aldosterone in serum, plasma, and urine.
Argonne material scientists have discovered a reaction that helps explain the behavior of a key electrolyte additive used to boost battery performance.
"This new method should allow us to explore a large ‘chemical space’ that had been essentially off-limits."
SLAC and Stanford scientists have discovered how some archaea thrive where other organisms would starve: Their crystalline shells not only protect them from the environment, but they also draw in nutrients through nanosized pores. Those nutrients concentrate in the space between the shell and the microbial cell, so what looks like a famine turns into a feast.
Benjamin A.Garcia, PhD, an expert in quantitative proteomics has been awarded the Biemann Medal by the American Society for Mass Spectrometry (ASMS). The early-career award recognizes significant achievement in basic or applied mass spectrometry. Garcia’s lab has develop
New Technique that Shows How a Protein “Light Switch” Works May Enhance Biological Research
Scientists at Los Alamos National Laboratory and the U.S. Army Research Laboratory in Aberdeen, Maryland have developed a novel “melt-cast” explosive material that could be a suitable replacement for Trinitrotoluene, more commonly known as TNT.
A new study co-led by University of Iowa researchers helps clarify how ammonia is present in Earth’s upper atmosphere. Using computer modeling, the researchers found ammonia molecules trapped in liquid cloud droplets are released during convection where these particles freeze and subsequently collide in the upper atmosphere.
Profiled is Zili Wu of the Department of Energy’s Oak Ridge National Laboratory, who leads ORNL’s Surface Chemistry and Catalysis group and conducts research at the Center for Nanophase Materials Sciences, a DOE Office of Science User Facility at ORNL.
Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the University of California San Diego has now launched a new Center for Anti-Parasitic Drug Discovery and Development to address this unmet need in global health.
a team led by researchers at UC San Diego’s Department of Chemistry and Biochemistry and the San Diego Supercomputer Center (SDSC), has used machine learning techniques to develop models for simulations of water with “unprecedented accuracy.”
Peter T. Meinke, PhD, an accomplished chemist with more than 30 years of industry and academic experience, has been selected to lead the Tri-Institutional Therapeutics Discovery Institute.
Scientists, biotech, engineering and commercial building and design professionals are gathering at the Life Sciences Real Estate Development Symposium today to reimagine New York City using biology, and to thoughtfully begin planning for building new environments to accommodate projected rapid expansion of applied life sciences in the City and globally. The newly forming NYC Builds Bio+ initiative, an interdisciplinary collaborative organization of leaders in real estate and life sciences, will be announced at the meeting in response to the projected unprecedented decade of growth ahead.
News Release RICHLAND, Wash. — ASTM International recently revised ASTM D7566 Annex A5 — the Standard Specification for Aviation Turbine Fuel Containing Synthesized Hydrocarbons — to add ethanol as an approved feedstock for producing alcohol-to-jet synthetic paraffinic kerosene (ATJ-SPK). The revision of ASTM D7566 Annex A5 clears the way for increased adoption of sustainable aviation fuels because ethanol feedstocks can be made from so many different low-cost sources.
Experiments conducted at the Department of Energy’s Lawrence Berkeley National Laboratory helped to confirm that samples of interplanetary particles – collected from Earth’s upper atmosphere and believed to originate from comets – contain dust leftover from the initial formation of the solar system.
By Julie Hammonds Office of the Vice President for ResearchA Northern Arizona University physicist who studies complex, hybrid nanomaterials has been recognized for his academic leadership and the quality and innovation of his research. The Research Corporation for Science Advancement (RCSA) recently named assistant professor John Gibbs a 2018 Cottrell Scholar.
Oxygen photosynthesis has to be the greatest giver of life on Earth, and researchers have cracked yet another part of its complex and efficient chemistry. The more we know about it, the better we may be able to tweak photosynthesis, if it comes under environmental duress. It's also a great teacher of how to harvest sheer unlimited energy from the sun.
ISCA Technologies, a Riverside, Calif. biotech firm, has acquired from Scotts Canada, Ltd., a subsidiary of The Scotts Miracle-Gro Company, intellectual property rights and assets developed by the Canadian company Contech to control insects and other pests in ways that greatly reduce reliance on harmful chemical pesticides.
By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience
Mark Salvatore, who studied the surface of the Red Planet, also is part of a team that collaborates with scientists, engineers and NASA's rover operations to guide the Curiosity around Mars.
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