Feature Channels: Pharmaceuticals

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Released: 21-Jan-2020 3:35 PM EST
Improving Cardiovascular Health of the Most Vulnerable
University of North Carolina School of Medicine

Starting in 2016, a two-year partnership between the North Carolina Chapter of the American College of Cardiology (NCACC) and the North Carolina Association of Free and Charitable Clinics (NCAFCC) provided free lipid lowering therapy and clopidogrel to patients at seven free clinics in North Carolina. The results of this pilot study were recently published in the Journal of the American College of Cardiology.

Released: 21-Jan-2020 2:20 PM EST
Why Experts Are Worried About a New Virus in China
Council on Foreign Relations (CFR)

The virus appears to be less dangerous than SARS, but there are still concerns of a wider outbreak in Asia.

Released: 21-Jan-2020 11:05 AM EST
Clinical Trial: Vitamin D Supplementation Linked to Potential Improvements in Blood Pressure in Children
Health Sciences at the University of Pittsburgh

Overweight and obese vitamin D-deficient children who took a relatively high dose of vitamin D every day for six months had lower blood pressure and improved insulin sensitivity than their peers who took a lower dose, according to the results of a new clinical trial.

Released: 21-Jan-2020 1:05 AM EST
New Policy Reduces Anti-Psychotic Medications in Foster Children
Rutgers University-New Brunswick

Rutgers researchers have found that a Texas strategy to reduce anti-psychotic medication for children can serve as a model for other state Medicaid programs.

17-Jan-2020 10:05 AM EST
While Promoting Diseases Like Cancer, These Enzymes Also Cannibalize Each Other
Georgia Institute of Technology

In diseases like cancer, atherosclerosis, and sickle cell anemia, cathepsins promote their propagation. Drug trials to inhibit these enzymes have failed due to baffling side effects. Now a new study examines cathepsins in systems to remove some of the bafflement.

19-Jan-2020 11:05 AM EST
Dozens of potential anti-cancer drugs netted in massive screening study
Dana-Farber Cancer Institute

A variety of existing drugs for treating conditions such as diabetes, inflammation, alcohol abuse, and arthritis in dogs can also kill cancer cells in the lab, according to a study by scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Released: 20-Jan-2020 10:50 AM EST
New Drug Prevents Liver Damage, Obesity and Glucose Intolerance in Mice on High-Fat Diet
Lombardi Comprehensive Cancer Center at Georgetown University

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body’s glucose balance.

   
Released: 17-Jan-2020 10:25 AM EST
Acid reflux drugs may have negative side effects for breast cancer survivors
Ohio State University

Acid reflux drugs that are sometimes recommended to ease stomach problems during cancer treatment may have an unintended side effect: impairment of breast cancer survivors’ memory and concentration.

16-Jan-2020 11:50 PM EST
JAMA editorial helps set record straight on unproven sepsis therapy
University of Nebraska Medical Center (UNMC)

The Jan. 17 issue of the Journal of the American Medical Association (JAMA) features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert. The study and editorial sets the record straight on an unproven therapy some physicians use to treat sepsis, a deadly infectious disease. The editorial, written by Andre Kalil, M.D., M.P.H., professor of infectious diseases in the UNMC Department of Internal Medicine, writes in support of the new and rigorous international study based on a randomized clinical trial in Australia, published in the same issue. The editorial appears in the Jan. 17 online issue and also will appear in the Feb. 4 print edition.

Released: 17-Jan-2020 12:20 AM EST
Putting the ‘lazy eye' to work
University of California, Irvine

When University of California, Irvine neurobiologist Carey Y.L. Huh, Ph.D., set her sights on discovering more about amblyopia, she brought personal insight to her quest. As a child, Huh was diagnosed with the condition, which is often called “lazy eye.” he and her colleagues have just found that amblyopia originates in an earlier stage of the visual pathway than was previously thought. Their research, which raises the possibility of new treatment approaches, appears in the Journal of Neuroscience.

Released: 16-Jan-2020 11:00 AM EST
Most Youths Surviving Opioid Overdose Not Getting Timely Treatment to Avoid Recurrence
Johns Hopkins Medicine

A study of more than 4 million Medicaid claims records during a recent seven-year period concludes that less than a third of the nearly 3,800 U.S. adolescents and young adults who experienced a nonfatal opioid overdose got timely (within 30 days) follow-up addiction treatment to curb or prevent future misuse and reduce the risk of a second overdose.

Released: 16-Jan-2020 8:05 AM EST
Special delivery: McMaster physicists design ‘super-human’ red blood cells to deliver drugs to specific targets within the body
McMaster University

A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs throughout the body, which could specifically target infections or treat catastrophic diseases such as cancer or Alzheimer’s.

13-Jan-2020 5:05 PM EST
Why can’t Bertrand Might cry? Scientists offer an answer: missing water channels
Sanford Burnham Prebys

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency—a rare disorder first described in 2012—lack sufficient water channel proteins called aquaporins. The discovery was published in Cell Reports and may help explain the disorder’s wide-ranging symptoms—including the inability to produce tears, seizures and developmental delays—and opens new avenues to find therapies to treat the disorder.

13-Jan-2020 5:50 PM EST
Global Team Enables Child With a Fatal Genetic Disease to Recover
Mount Sinai Health System

A young boy with a rare genetic disease that typically kills within weeks of birth is now 3 years old and in remission thanks to a collaborative effort that included physicians at King Saud University Department of Pediatrics and immunologists at the Icahn School of Medicine at Mount Sinai.

10-Jan-2020 3:15 PM EST
Study: MS Drug Costs Nearly Triple over Seven Years, Even with Introduction of Generic
American Academy of Neurology (AAN)

The cost of prescriptions for multiple sclerosis (MS) drugs nearly tripled over seven years, and the introduction of a generic version of one of the most common drugs had little overall effect on prices, according to a study published in the January 15, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

15-Jan-2020 10:50 AM EST
Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling
University of Alabama at Birmingham

Preclinical research has revealed a key missing piece of the Alzheimer’s disease puzzle. That allowed proof-of-concept experiments — using an existing drug — that dramatically reduced Alzheimer’s pathology and symptoms in mouse models, potentially offering an immediate treatment for this disease.

Released: 14-Jan-2020 1:45 PM EST
Hohe Insulinkosten sind für Diabetespatienten lebensbedrohlich
Mayo Clinic

Die am häufigsten verwendeten Formen von Insulin kosten in den USA 10-mal mehr als in jedem anderen Industrieland, wie aus einem Kommentar in Mayo Clinic Proceedings hervorgeht.

Released: 14-Jan-2020 1:45 PM EST
Reduced Inhaler Use is Safe for Infants with Bronchiolitis
Children's Hospital of Philadelphia

Bronchiolitis, a lung infection that is one of the most common reasons for hospitalizations in young children, is most prevalent during the winter months and is usually treated with albuterol delivered via inhalers, despite evidence showing no benefit in most patients. A multidisciplinary team of researchers from Children’s Hospital of Philadelphia (CHOP) redesigned the hospital’s standard treatment for the infection and reduced albuterol use without compromising care.

Released: 14-Jan-2020 1:40 PM EST
Exosomes promote remarkable recovery in stroke
University of Georgia

Scientists present brain-imaging data for a new stroke treatment that supported full recovery in swine, modeled with the same pattern of neurodegeneration as seen in humans with severe stroke.

Released: 14-Jan-2020 12:25 PM EST
Le coût élevé de l'insuline a des répercussions sur la vie ou la mort des patients diabétiques
Mayo Clinic

Les formes d'insuline les plus couramment utilisées coûtent 10 fois plus cher aux États-Unis que dans tous les autres pays développés, selon un commentaire publié dans la revue Mayo Clinic Proceedings.

Released: 14-Jan-2020 12:10 PM EST
آثار ارتفاع تكلفة الأنسولين على حياة مرضى السكري
Mayo Clinic

تزيد تكلفة أشكال الأنسولين الأكثر استخدامًا في الولايات المتحدة بمقدار 10 مرات عن أي دولة من الدول المتقدمة الأخرى، وفقًا لتعليق في مجلة Mayo Clinic Proceedings. وبسبب هذه التكلفة الباهظة، يلجأ بعض مرضى السكري من النوع الأول في الولايات المتحدة إلى الاقتصاد في كمية الأنسولين التي يستخدمونها، الأمر الذي له تداعيات تهدد حياتهم.

Released: 14-Jan-2020 10:00 AM EST
Mayo Clinic launches its first Platform initiative
Mayo Clinic

Mayo Clinic announced the Clinical Data Analytics Platform as the first venture under the Mayo Clinic Platform, a strategic initiative to improve health care through insights and knowledge derived from data.

Released: 13-Jan-2020 6:05 PM EST
John Theurer Cancer Center Investigators Report Effectiveness of New Treatment for Refractory Multiple Myeloma
Hackensack Meridian Health

Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey were part of the CANDOR global phase III clinical trial for patients with refractory (persistent) multiple myeloma. The study was selected as the prestigious plenary presentation at the 61st American Society of Hematology (ASH) Annual Meeting, the world's leading conference for hematologic cancers and blood disorders, held in Orlando in December.

Released: 13-Jan-2020 12:15 PM EST
New AACC Guidance Document Outlines How Healthcare Professionals Can Prevent the Widespread Supplement Biotin From Interfering With Medical Tests
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

Biotin’s upsurge in popularity has led to a parallel rise in incidents of this health supplement interfering with critical medical tests. A new guidance document from AACC urges clinicians and laboratory experts to collaborate to prevent this potentially harmful test interference, and to ensure that patients taking biotin receive high quality care.

Released: 13-Jan-2020 11:55 AM EST
How Marijuana Accelerates Growth of HPV-related Head and Neck Cancer Identified
UC San Diego Health

University of California San Diego School of Medicine researchers identified how THC from marijuana accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck cancer.

Released: 10-Jan-2020 11:25 AM EST
Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders
Mayo Clinic

A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered.

8-Jan-2020 4:05 PM EST
Taking One for the Team: How Bacteria Self-Destruct to Fight Viral Infections
UC San Diego Health

UC San Diego School of Medicine researchers have discovered how a new immune system works to protect bacteria from phages, viruses that infect bacteria — new information that could be leveraged to improve treatment of multidrug-resistant bacterial infections by refining phage therapy.

Released: 10-Jan-2020 8:35 AM EST
Antibiotics could be promising treatment for form of dementia
University of Kentucky

Researchers at the University of Kentucky’s College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.

9-Jan-2020 8:00 PM EST
Re-purposing existing drug could expedite development of novel chronic pain treatment caused by burn injury, helping sufferers including veterans
American Physiological Society (APS)

New research shows how second-degree burns cause hard-to-treat chronic pain, and this understanding may be key to treating these complications, common in war veterans.

Released: 9-Jan-2020 1:45 PM EST
Harnessing Biology and Technology to Develop New Depression Treatments – Update from Harvard Review of Psychiatry
Wolters Kluwer Health: Lippincott

New research into the biology of depression, along with new and evolving technologies, provides the basis for developing the next generation of treatments for major depressive disorder (MDD), according to the special January/February issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 9-Jan-2020 12:25 PM EST
Less Severe Cases of Diarrheal Illness Can Still Lead to Child Deaths, Research Shows
University of Maryland School of Medicine

Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age. Now, researchers at the University of Maryland School of Medicine (UMSOM) found that even milder cases of diarrheal diseases can lead to death in young children.

Released: 9-Jan-2020 10:05 AM EST
Study: How U.S. sewage plants can remove medicines from wastewater
University at Buffalo

A study of seven wastewater treatment plants points to two treatment methods — granular activated carbon and ozonation — as being particularly promising for reducing the concentration of pharmaceuticals including certain antidepressants and antibiotics.

7-Jan-2020 12:00 AM EST
Penn Medicine Shows Giving Entire Course of Radiation Treatment in Less Than a Second is Feasible
Perelman School of Medicine at the University of Pennsylvania

Cancer patients may one day be able to get their entire course of radiation therapy in less than a second rather than coming in for treatment over the course of several weeks, and researchers in the Abramson Cancer Center of the University of Pennsylvania have taken the first steps toward making it a reality

Released: 8-Jan-2020 4:15 PM EST
FSU study aids fight against HIV, hepatitis B
Florida State University

A discovery by Florida State University College of Medicine researchers is expected to open the door for new and more potent treatment options for many of the more than 36 million people worldwide infected with the HIV virus and for others chronically ill with hepatitis B.

Released: 8-Jan-2020 3:45 PM EST
This drug could save their lives, but less than 2% of them get it
Michigan Medicine - University of Michigan

Only a tiny minority of people at risk for an opioid overdose actually are prescribed a drug that could save their lives, a new study suggests. And the odds of having a dose of the rescue drug were very low among some of the most at-risk groups, including those who had already survived a previous opioid overdose.

Released: 8-Jan-2020 3:00 PM EST
House Energy and Commerce Committee Holds Hearing on Immunosuppressive Drug Coverage, a Key Legislative Priority of American Society of Nephrology
American Society of Nephrology (ASN)

Washington, DC (January 8, 2020) — The House Energy and Commerce Committee is scheduled to hold a hearing on Wednesday, January 8, on the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act of 2019, advancing a long-standing legislative priority of the American Society of Nephrology.

Released: 8-Jan-2020 2:45 PM EST
Could pancreatitis be a stress hormone deficiency?
UT Southwestern Medical Center

UT Southwestern researchers find that humans and mice with pancreatitis are deficient in a stress hormone called FGF21.

Released: 8-Jan-2020 12:15 PM EST
Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone
University of Colorado Cancer Center

Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow

Released: 8-Jan-2020 11:35 AM EST
Tissue-Engineering, Estrogenic Chemical–Induced Responses, and Life-Stage Physiologically Based Pharmacokinetic Modeling Featured in January 2020 Toxicological Sciences
Society of Toxicology

In addition to research exploring such areas as biomarkers, nano- and neurotoxicology, and developmental and reproductive toxicology, the January 2020 issue of Toxicological Sciences features a new article category, ToxPoint, to underscore cutting-edge topics in toxicology.

   
Released: 7-Jan-2020 12:40 PM EST
Million Veteran Program study sheds light on genetic basis of anxiety
Veterans Affairs (VA) Research Communications

In the largest genetic study on anxiety to date, VA researchers found new evidence on the underlying biological causes of the disorder.

Released: 7-Jan-2020 10:50 AM EST
Research shows nasal spray antidote is easiest to give for opioid overdose
Binghamton University, State University of New York

Of three possible ways for people to deliver the life-saving antidote naloxone to a person experiencing an opioid overdose, the use of a nasal spray was the quickest and easiest according to research conducted by William Eggleston, clinical assistant professor at Binghamton University, State University of New York, and colleagues at SUNY Upstate Medical University.

Released: 7-Jan-2020 8:30 AM EST
Analysis of FDA Documents Reveals Inadequate Monitoring of Key Program to Promote Safe Opioid Use
Johns Hopkins Bloomberg School of Public Health

A risk-management program set up in 2012 by the U.S. Food and Drug Administration to curb improper prescribing of extended-release and long-acting opioids may not have been effective because of shortcomings in the program’s design and execution, according to a paper from researchers at the Johns Hopkins Bloomberg School of Public Health.

Released: 7-Jan-2020 6:05 AM EST
Discovery Could Lead to New Breast Cancer Drugs
University of New Mexico Comprehensive Cancer Center

Eric Prossnitz, PhD, and his team have recently completed studies on a compound that they think could be made to attack breast cancer cells differently than current drugs. Their work is reported in the November online issue of Cell Chemical Biology. This newly discovered behavior could turn the chemical into potent breast cancer drugs

17-Dec-2019 8:05 AM EST
ISPOR Publishes 2020 Top 10 Health Economics and Outcomes Research (HEOR) Trends Report
ISPOR—The Professional Society for Health Economics and Outcomes Research

ISPOR—the professional society for health economics and outcomes research (HEOR), announced the publication of its 2020 Top 10 HEOR Trends report. In the report, the Society has identified the top 10 HEOR trends that will shape the field and influence healthcare over 2020 and the near future.

2-Jan-2020 8:35 AM EST
Children Frequently Receive Unnecessary Medical Care Regardless of Insurance Type
Michigan Medicine - University of Michigan

Children with public insurance are slightly more likely to receive medical services that they don’t need than those with private insurance, a new study finds.

Released: 6-Jan-2020 3:05 PM EST
Cannabis Edibles Present Novel Health Risks
Canadian Medical Association (CMA)

With the recent legalization of cannabis edibles in Canada, physicians and the public must be aware of the novel risks of cannabis edibles

3-Jan-2020 11:20 AM EST
Finding a new way to fight late-stage sepsis
Ohio State University

Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body’s extreme reaction to infection.

Released: 3-Jan-2020 4:35 PM EST
Eine Studie hat ergeben, dass eine weniger aggressive Chemotherapie nach der Erstbehandlung von metastasiertem Kolorektalkarzinom vorteilhafter ist
Mayo Clinic

Ein Studie von Mayo Clinic an 5540 Patienten mit metastasiertem kolorektalem Karzinom hat ergeben, dass für Patienten, deren Krankheit unter Kontrolle ist, eine Erhaltungs-Chemotherapie nach der Erstbehandlung nützlicher als eine aggressivere Behandlung ist.



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