Feature Channels: Diabetes

• share
• favorite_border

UCSF Analysis Suggests Penny-Per-Ounce Tax on Sugary Beverages Would Prevent Heart Disease, Stroke and Diabetes and Save Billions in Healthcare Costs.

• share
• favorite_border

To address the prospects for personalized medicine in diabetes, investigators from Albert Einstein College of Medicine have surveyed the field for existing research and published their findings in the January issue of Health Affairs. The authors are Allen M. Spiegel, M.D., the Marilyn and Stanley M. Katz Dean and former director of the National Institute of Diabetes and Digestive and Kidney Diseases at the NIH, and Meredith Hawkins, M.D., director of Einstein’s Global Diabetes Initiative.

• share
• favorite_border

Hyperglycemia, or having high glucose levels in the blood, is a common, serious and costly health care problem in hospitalized patients. Today, The Endocrine Society released a clinical practice guideline (CPG) providing recommendations for practical and safe glycemic targets and describing protocols and system improvements required to achieve glycemic goals for hospitalized patients in a non-critical care setting.

• share
• favorite_border

Researchers at Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine and colleagues have discovered a new protein that may play a critical role in how the human body regulates blood sugar levels. Reporting in the current issue of Pancreas, the research team says the protein may represent a new target for treating type 1 diabetes.

• share
• favorite_border

People with diabetes may one day have a less expensive resource for monitoring their blood glucose levels, if research by a group of Missouri University of Science and Technology students becomes reality.

• share
• favorite_border

Community food banks may soon be able to improve how the estimated millions of people living with Type 2 diabetes and food insecurity manage their disease. Researchers and community groups have come together to develop a model that ensures food banks can contribute to successful, long-term diabetes management.

• share
• favorite_border

Diabetes expert says being over supplied, preparing for security checks and anticipating time zone changes can make travelling easier and safer.

• share
• favorite_border

Exercising harder, but for a shorter period, may have significant benefits for some with type 2 diabetes.

• share
• favorite_border

If the festive season tempts your tastebuds to overindulge, learn to prevent holiday weight gain with these 10 tips from the team of medical experts at Greenwich Hospital’s Weight Loss & Diabetes Center

• share
• favorite_border

Researchers at McMaster University have found that brief high intensity workouts, as little as six sessions over two weeks, rapidly lower blood sugar levels in type 2 diabetics, offering a potential fix for patients who struggle to meet exercise guidelines.

• share
• favorite_border

• Diabetes and obesity after age 60 are independent risk factors for breast cancer. • Abnormally low blood lipids were found to increase breast cancer risk. • Use of a specific diabetes drug is indicated in raising cancer risk.

• share
• favorite_border

Study suggests that exercise and one of the most commonly prescribed drugs for diabetes, metformin, each improves insulin resistance when used alone, but together, metformin blunted the full effect of a 12-week exercise program in pre-diabetic men and women.

• share
• favorite_border

A recent study of obese and non-obese children found that low vitamin D levels are significantly more prevalent in obese children and are associated with risk factors for type 2 diabetes. This study was accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

• share
• favorite_border

A war is being waged in the pancreases of millions of people throughout the world. The siege leads to the development of type 1 diabetes and has been a battlefield largely hidden from view-- until now. Researchers at the La Jolla Institute for Allergy & Immunology have created the first cellular movies showing the destruction underlying type 1 diabetes in real-time in mouse models. This detailed, dynamic view will provide the worldwide scientific community insights into this disease process as never before possible and may profoundly affect future directions in type 1 diabetes research.

• share
• favorite_border

In 2009, the American Diabetes Association (ADA) recommended that Hemoglobin A1c be exclusively used for the diagnosis of diabetes in children. The simple test measures longer-term blood sugar levels -- without requiring patients to fast overnight. However, a new U-M study has shown that these tests are not very accurate in children.

• share
• favorite_border

Jay A. Perman, MD, President of the University of Maryland, and Joshua M. Sharfstein, MD, Secretary of the Maryland Department of Health and Mental Hygiene (DHMH), announced today the creation of the Institute for a Healthiest Maryland, a collaboration of support systems that will guide efforts to combat chronic diseases across Maryland.

• share
• favorite_border

Infertility is common among obese women, but the reasons remain poorly understood and few treatments exist. Now a team of Johns Hopkins Children's Center scientists, conducting experiments in mice, has uncovered what they consider surprising evidence that insulin resistance, long considered a prime suspect, has little to do with infertility in women with type-2 diabetes, polycystic ovary syndrome (PCOS) and metabolic syndrome, all obesity-related conditions in which the body becomes desensitized to insulin and loses the ability to regulate blood sugar.

• share
• favorite_border

Highlights: 1) People with type 1 diabetes are at high risk of developing kidney disease. 2) Intensive diabetes therapy can preserve kidney function in patients with type 1 diabetes. 3) Between one million and three million Americans may have type 1 diabetes. Each year, more than 15,000 children and 15,000 adults - approximately 80 people per day - are diagnosed with type 1 diabetes in the United States.

• share
• favorite_border

Highlights: 1) Sitagliptin is as effective as glipizide at lowering blood sugar levels in patients with type 2 diabetes and chronic kidney disease. 2) Sitagliptin is less likely than glipizide to cause dangerously low blood sugar levels. 3) Patients on sitagliptin tend to lose weight, while those on glipizide gain weight.

• share
• favorite_border

Highlights: 1) Diabetic patients with kidney failure benefit the most when their hemoglobin A1C levels, which reflect blood glucose levels, are between 7% and 8%. 2) For diabetics who need dialysis, hemoglobin A1C levels of 8% or greater or less than 7% put them at increased risk of dying prematurely compared to patients with levels between 7.0% and 7.9%.

• share
• favorite_border

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

• share
• favorite_border

An Ithaca College study finds that diabetics who see themselves responsible for the onset of their disease are less likely to manage it.

• share
• favorite_border

Researchers at Albert Einstein College of Medicine of Yeshiva University have demonstrated for the first time that the brain is a key player in regulating glucose (sugar) metabolism in humans. The findings, published today in the online edition of the Journal of Clinical Investigation, suggest that drugs targeting the brain and central nervous system could be a novel approach to treating diabetes.

• share
• favorite_border

Half of all American adults are destined to develop diabetes or pre-diabetes by 2020 if they don't make dramatic lifestyle changes, according to a dire new prediction from the Centers for Disease Control and Prevention. If current trends continue, the ranks of American adults with excessive blood sugar levels would swell from 93.8 million this year (about 28 million diabetics and 66 million more with pre-diabetes) to 135 million in 2020 – and cost society $3.35 billion by decade’s end. In addition, diabetes is becoming one of the most common chronic diseases in children and adolescents. According to the American Diabetes Association, one in every four children is currently diagnosed with diabetes. Dr. Joel Zonszein believes that unless healthy lifestyle changes are made early in life, diabetes could become an epidemic of tsunami-like proportions. Montefiore has been collaborating with the Diabetes Research Center and Training Center (DRTC), focusing on diabetes education, professional

• share
• favorite_border

Exenatide, a drug commonly prescribed to help patients with type 2 diabetes improve blood sugar control, also has a powerful and rapid anti-inflammatory effect, a University at Buffalo study has shown.

• share
• favorite_border

Pediatric researchers who tested newborn animals with a human drug used in adults with diabetes report that this drug, when given very early in life, prevents diabetes from developing in adult animals.

• share
• favorite_border

DARA's DB959 Phase 1b clinical study for the treatment of type 2 diabetes - results demonstrated that DB959 is safe and well-tolerated and show support for pharmacological activity.

• share
• favorite_border

Sleep, hormones, weight, exercise and genetics are all related to diabetes, affecting one in three Americans. November is Diabetes Awareness Month. Experts available for radio, TV and print.

• share
• favorite_border

A recent study has found that a childhood behavioral intervention to lower dietary intake of total fat and saturated fat and increase consumption of foods that are good sources of dietary fiber resulted in significantly lower fasting plasma glucose levels and lower systolic blood pressure when study participants were re-evaluated in young adulthood. The study was accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology and Metabolism (JCEM).

• share
• favorite_border

Learn what's new in diabetes prevention and research.

• share
• favorite_border

In a paper published today in Diabetologia, a team at Joslin Diabetes Center, headed by Mary R. Loeken, PhD, has identified the enzyme AMP kinase (AMPK) as key to the molecular mechanism that significantly increases the risk of neural tube defects such as spina bifida and some heart defects among babies born to women with diabetes.

• share
• favorite_border

Researchers at the University of Pennsylvania School of Nursing encourage kids at risk for diabetes to get footloose.

• share
• favorite_border

Calories, not sugar, contribute to diabetes, and there is hope for people with Type 2 diabetes. Read what other diabetes myths need to be dispelled.

• share
• favorite_border

Diabetics who suffer from hard-to-heal open wounds may soon have help in the form of a cottony glass material developed at Missouri University of Science and Technology.

• share
• favorite_border

More than Half of All Americans Will Have Diabetes by 2020 – Ranks Could Swell to 135 million Half of all American adults are destined to develop diabetes or pre-diabetes by 2020 if they don't make dramatic lifestyle changes, according to a dire new prediction from the Centers for Disease Control and Prevention. If current trends continue, the ranks of American adults with excessive blood sugar levels would swell from 93.8 million this year (about 28 million diabetics and 66 million more with pre-diabetes) to 135 million in 2020 – and cost society $3.35 billion by decade’s end. In addition, diabetes is becoming one of the most common chronic diseases in children and adolescents. According to the American Diabetes Association, one in every four children is currently diagnosed with diabetes. Dr. Joel Zonszein believes that unless people improve their diet and exercise more regularly, diabetes could become an epidemic of tsunami-like proportions.

• share
• favorite_border

Patients with diabetes face daily challenges in managing their blood glucose levels, and it has been postulated that patients could benefit from a system providing continuous real-time glucose readings. Today, The Endocrine Society released a clinical practice guideline (CPG) providing recommendations on settings where patients are most likely to benefit from continuous glucose monitoring (CGM).

• share
• favorite_border

Carb counting and insulin pumps help diabetic kids sample Halloween’s sweet indulgences.

• share
• favorite_border

Cardium Therapeutics (CXM) has received FDA 510(k) clearance to market and sell Excellagen™ professional-use advanced wound care product for diabetic foot ulcers, pressure ulcers and other dermal wounds.

• share
• favorite_border

Ten years of meticulous mouse breeding, screening, and record-keeping have finally paid off for Alan Attie and his lab members.

• share
• favorite_border

Excessive food AGEs, through both maternal blood transmission and baby formula, could together significantly increase children’s risk for diseases such as diabetes from a very young age. A second study of AGEs in adults found that cutting back on processed, grilled, and fried foods may improve insulin resistance in people with diabetes.

• share
• favorite_border

Researchers at Washington University School of Medicine in St. Louis have restored normal blood sugar metabolism in diabetic mice using a compound the body makes naturally. The finding suggests that it may one day be possible for people to take the compound much like a daily vitamin as a way to treat or even prevent type 2 diabetes.

• share
• favorite_border

The largest-ever analysis of genetic data related to type 1 diabetes has uncovered new genes associated with the common metabolic disease, which affects 200 million people. The findings shed light on gene networks in the disorder.

• share
• favorite_border

In a paper published in the September 30 issue of the journal Cell, researchers at the University of California San Diego School of Medicine and colleagues offer an explanation, and a framework that could lead to dietary supplements designed to treat obesity at the molecular level.

• share
• favorite_border

Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes. Though this variant is not likely the cause of more severe coronary disease, the researchers say, it implicates a gene that could be. Such a gene has promise as a future target for treating coronary artery disease in diabetic patients.

• share
• favorite_border

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

• share
• favorite_border

The American Association of Clinical Endocrinologists (AACE) and Takeda Pharmaceuticals North America Inc. (Takeda) have partnered to launch the Diabetes Navigator (http://DiabetesNavigator.AACE.com), a compendium capturing a selection of useful and reliable type 2 diabetes information available online for patients and caregivers.

• share
• favorite_border

Researchers at the Salk Institute have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin.

• share
• favorite_border

Visiting a primary care clinician every two weeks was associated with greater control of blood glucose, blood pressure and cholesterol levels among patients with diabetes, according to a report in the September 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

• share
• favorite_border

In an early preclinical study in mice, UCLA researchers demonstrated that an over-the-counter dietary supplement may help inhibit development of insulin resistance and glucose intolerance, conditions that are involved in the development of Type 2 diabetes and metabolic syndrome.

• share
• favorite_border

UAB’s Diabetes Bridge Clinic helps patients keep symptoms under control during the vulnerable period as they go from hospital to home.