Feature Channels: Biotech

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Released: 26-May-2023 12:00 PM EDT
Tissue-specific cancer stem/progenitor cells: Therapeutic implications
World Journal of Stem Cells

Surgical resection, chemotherapy, and radiation are the standard therapeutic modalities for treating cancer. These approaches are intended to target the more mature and rapidly dividing cancer cells. However, they spare the relatively quies

Released: 26-May-2023 12:00 PM EDT
Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations
World Journal of Stem Cells

Colorectal cancer (CRC) remains the third most prevalent cancer disease and involves a multi-step process in which intestinal cells acquire malignant characteristics. It is well established that the appearance of distal metastasis in CRC pa

Released: 26-May-2023 12:00 PM EDT
How the interplay among the tumor microenvironment and the gut microbiota influences the stemness of colorectal cancer cells
World Journal of Stem Cells

Colorectal cancer (CRC) remains the third most prevalent cancer disease and involves a multi-step process in which intestinal cells acquire malignant characteristics. It is well established that the appearance of distal metastasis in CRC pa

Newswise: Medical
Released: 24-May-2023 12:15 PM EDT
Medical "microrobots" could one day treat bladder disease, other human illnesses
University of Colorado Boulder

A team of engineers at the University of Colorado Boulder has designed a new class of tiny, self-propelled robots that can zip through liquid at incredible speeds—and may one day even deliver prescription drugs to hard-to-reach places inside the human body.

   
Newswise: Artificial Pancreas Reduces Disease Management Burden for People with Diabetes
18-May-2023 3:15 PM EDT
Artificial Pancreas Reduces Disease Management Burden for People with Diabetes
American Institute of Physics (AIP)

In APL Bioengineering, researchers design a novel algorithm for controlling implanted insulin pumps that accounts for the unique characteristics of individual patients. Their model, tested using an FDA-approved diabetes computer simulation, proves intraperitoneal (within the abdominal cavity) insulin delivery is fast and closely mimics natural physiological insulin delivery. They developed a model that can account for individual patient differences and validated a pump control algorithm that does not require meal announcement.

Newswise: Scientists at Wake Forest University School of Medicine Discover Metabolic Sensor May Play Role in Alzheimer’s Disease
Released: 22-May-2023 1:05 PM EDT
Scientists at Wake Forest University School of Medicine Discover Metabolic Sensor May Play Role in Alzheimer’s Disease
Wake Forest University School of Medicine

Scientists at Wake Forest University School of Medicine have uncovered a novel mechanism that shows increased sugar intake and elevations in blood glucose are sufficient to cause amyloid plaque buildup in the brain, which increases the risk of Alzheimer’s disease.

Newswise: A New Strategy to Break Through Bacterial Barriers in Chronic Treatment-Resistant Wounds
Released: 22-May-2023 9:45 AM EDT
A New Strategy to Break Through Bacterial Barriers in Chronic Treatment-Resistant Wounds
University of North Carolina School of Medicine

Researchers in UNC’s School of Medicine’s department of Microbiology and Immunology and the UNC-NC State Joint Department of Biomedical Engineering have developed a new strategy to improve drug-delivery into chronic wounds infections.

Released: 22-May-2023 8:05 AM EDT
Arthrex Launches Patient Education Website for ACL Injuries
Arthrex, Inc.

Arthrex, a global leader in minimally invasive orthopedic technology, launched a new patient-focused website, ACLTear.com, which illustrates the science of anterior cruciate ligament (ACL) injuries, highlights the benefits of knee preservation technology and provides tools to patients to connect with surgeons performing advanced, minimally invasive ACL procedures.

Newswise: Artificial Intelligence Catalyzes Gene Activation Research and Uncovers Rare DNA Sequences
Released: 19-May-2023 1:40 PM EDT
Artificial Intelligence Catalyzes Gene Activation Research and Uncovers Rare DNA Sequences
University of California San Diego

Biologists have used machine learning, a type of AI, to identify “synthetic extreme” DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and found synthetic DNA sequences with activities that could be useful in biotechnology and medicine.

Released: 18-May-2023 6:00 AM EDT
MEDIA ADVISORY: AACN's Critical Care Exposition Showcases Latest Equipment, Devices and More
American Association of Critical-Care Nurses (AACN)

The American Association of Critical-Care Nurses hosts its annual National Teaching Institute & Critical Care Exposition (NTI) May 22-24 in Philadelphia. NTI -- the world’s largest conference for nurses who care for acutely and critically ill patients -- includes the Critical Care Exposition, the largest and most comprehensive trade show specifically for progressive care and critical care nurses.

Released: 17-May-2023 1:20 PM EDT
Palouse Specialty Oncology & Hematology Selects CureMD Oncology as Their EMR/PM Provider to Provide Best-in-Class Cancer Care Services in the Region
CureMD

CureMD Oncology, a leading provider of all-inclusive technology solutions for community oncology, is delighted to announce its partnership with Palouse Specialty Physicians, a comprehensive cancer care provider in the Pacific Northwest region.

Newswise: Coronary Bioresorbable Scaffolds Nearly as Safe and Effective as Conventional Metal Stents for Heart Disease Patients
Released: 17-May-2023 9:00 AM EDT
Coronary Bioresorbable Scaffolds Nearly as Safe and Effective as Conventional Metal Stents for Heart Disease Patients
Mount Sinai Health System

First-generation bioresorbable vascular scaffolds (BVS) may be just as effective as drug-eluting metallic stents, which are currently the standard treatment for heart disease patients undergoing percutaneous coronary intervention (PCI).

Newswise: Simulation tools drive the new generation of therapies based on gene silencing
Released: 17-May-2023 5:05 AM EDT
Simulation tools drive the new generation of therapies based on gene silencing
Institute for Research in Biomedicine Barcelona

Proteins are large, complex molecules that play many critical roles in the body and are produced following the instructions encoded in DNA. By reading their DNA letters, cells produce an intermediate RNA molecule that will give rise to the corresponding protein. Most diseases occur with altered protein levels, which are either a cause or consequence of the condition itself. RNA plays a pivotal role in diseases with altered protein levels by serving as the intermediary messenger between DNA and protein.

   
Released: 16-May-2023 2:00 PM EDT
May is Melanoma and Skin Cancer Awareness Month. Keep up with the latest news on skin in the Dermatology channel
Newswise

Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.

Newswise: Engineers building tools to improve quality, production of disease-fighting cells
Released: 16-May-2023 12:05 PM EDT
Engineers building tools to improve quality, production of disease-fighting cells
Iowa State University

Iowa State University engineers are developing advanced tools for cell manufacturing that could improve the cost and availability of therapeutic cells capable of fighting diseases such as cancers, heart disease, lupus and other autoimmune diseases.

   
Newswise: Using urine to make sub-Saharan city region food systems more sustainable
Released: 12-May-2023 3:50 PM EDT
Using urine to make sub-Saharan city region food systems more sustainable
Institut de Recherche pour le Developpement (IRD)

To give the authorities a cross-sectoral view of a city’s nutrient sink status, the researchers identified and analysed a range of waste flows. Their approach distinguished four nested spatial levels: the urban area; the potential territorial recycling system; the country and the international level. Based on that analysis, the researchers focused on the origin and fate of those nutrient-containing waste flows.

Released: 11-May-2023 9:50 AM EDT
Picking up good vibrations – of proteins – at CHESS
Cornell University

A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and biochemistry.

10-May-2023 6:30 PM EDT
Next-generation statistical simulator gives medical and biological researchers a benchmarking tool capable of closely mimicking single-cell and spatial genomics data
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have developed an “all-in-one,” next-generation statistical simulator capable of assimilating a wide range of information to generate realistic synthetic data and provide a benchmarking tool for medical and biological researchers who use advanced technologies to study diseases and potential therapies.

   
Newswise: The copper key to more efficient biomass breakdown
Released: 10-May-2023 12:25 PM EDT
The copper key to more efficient biomass breakdown
Oak Ridge National Laboratory

Nonfood, plant-based biofuels have potential as a green alternative to fossil fuels, but the enzymes required for production are too inefficient and costly to produce. However, new research is shining a light on enzymes from fungi that could make biofuels economically viable.

Released: 10-May-2023 8:10 AM EDT
AI helps create better, simpler hepatitis, COVID-19 tests
University of Florida

Going beyond pregnancy and COVID-19, the world could someday soon come to rely on at-home tests for many diseases thanks in part to AI-fueled improvements.

   
Newswise: NSF awards Iowa researchers $20 million to build advanced biomanufacturing capacity
Released: 9-May-2023 4:50 PM EDT
NSF awards Iowa researchers $20 million to build advanced biomanufacturing capacity
Iowa State University

The National Science Foundation's program to build research capacity across the country has awarded a $20 million grant to support Iowa researchers working to make the state a leader in advanced biomanufacturing. The researchers will use microbes to produce plastics for 3D printing, fibers for flexible and rigid materials and proteins for medical diagnostics and therapeutics.

Newswise: The Wistar Institute, Pennsylvania Biotechnology Center and Baruch S. Blumberg Institute Forge Strategic Collaboration to Support Regional Biotech Startups
Released: 9-May-2023 10:05 AM EDT
The Wistar Institute, Pennsylvania Biotechnology Center and Baruch S. Blumberg Institute Forge Strategic Collaboration to Support Regional Biotech Startups
Wistar Institute

Wistar Institute has formed a collaboration with the Pennsylvania Biotechnology Center and the Baruch S. Blumberg Institute to accelerate the advancement of “bench to bedside” biomedical research discoveries in the tri-state region.

Released: 8-May-2023 3:45 PM EDT
UC Irvine scientists develop gene silencing DNA enzyme that can target a single molecule
University of California, Irvine

Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough “gene silencing” technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.

Newswise: Clearing the runway: Modeling a realistic supply chain for bio-based jet fuel
Released: 8-May-2023 3:30 PM EDT
Clearing the runway: Modeling a realistic supply chain for bio-based jet fuel
Oak Ridge National Laboratory

Oak Ridge National Laboratory scientists led the development of a supply chain model revealing the optimal places to site farms, biorefineries, pipelines and other infrastructure for sustainable aviation fuel production.

Newswise: U of M researchers develop technique for rapid detection of neurodegenerative diseases like Parkinson’s and Chronic Wasting Disease
Released: 8-May-2023 7:00 AM EDT
U of M researchers develop technique for rapid detection of neurodegenerative diseases like Parkinson’s and Chronic Wasting Disease
University of Minnesota College of Science and Engineering

University of Minnesota Twin Cities researchers have developed a groundbreaking new diagnostic technique that will allow for faster and more accurate detection of neurodegenerative diseases that affect humans, such as Alzheimer's and Parkinson's, and similar diseases that affect animals, such as chronic wasting disease (CWD) and mad cow disease.

   
Newswise: The Association of Biomolecular Resource Facilities 2023 Annual Meeting, May 7-10, Boston
Released: 5-May-2023 4:50 PM EDT
The Association of Biomolecular Resource Facilities 2023 Annual Meeting, May 7-10, Boston
Federation of American Societies for Experimental Biology (FASEB)

The Association of Biomolecular Resource Facilities (ABRF) 2023 Annual Meeting will be held May 7-10 at the Sheraton Boston Hotel.

Released: 4-May-2023 1:40 PM EDT
Leading Physician-Scientist Dr. Bradley A. Maron Appointed Senior Associate Dean for Precision Medicine at UMSOM and Co-Director of new University of Maryland Institute for Health Computing (UM-IHC) at UMB
University of Maryland School of Medicine

University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Bradley A. Maron, MD, Associate Professor of Medicine at Brigham & Women’s Hospital (BWH) and Harvard Medical School (HMS), and Co-Director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System, has been appointed Co-Director of the UMB’s new Institute for Health Computing (UM-IHC), Director of Scientific Operations for the UM-IHC at UMSOM, as well as Senior Associate Dean for Precision Medicine at the UMSOM, effective May 1, 2023.

   
Newswise: St. Jude tool gets more out of multi-omics data
Released: 4-May-2023 12:05 PM EDT
St. Jude tool gets more out of multi-omics data
St. Jude Children's Research Hospital

An upgraded computational tool from St. Jude Children’s Research Hospital can find potentially druggable hidden drivers of cancer and other biological processes using multi-omics data.

   
Released: 2-May-2023 6:35 PM EDT
Quantum entanglement of photons doubles microscope resolution
California Institute of Technology

Using a “spooky” phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes.

Newswise: Could Wearables Capture Well-being?
28-Apr-2023 5:05 PM EDT
Could Wearables Capture Well-being?
Mount Sinai Health System

Applying machine learning models, a type of AI, to data collected passively from wearable devices can identify a patient’s degree of resilience and well-being, according to investigators at the Icahn School of Medicine at Mount Sinai in New York. The findings, reported in the May 2nd issue of JAMIA Open, support wearable devices, such as the Apple Watch®, as a way to monitor and assess psychological states remotely without requiring the completion of mental health questionnaires.

Released: 1-May-2023 6:15 PM EDT
Chances of eliminating HIV infection increased by novel dual gene-editing approach
Temple University Health System

Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection. The study is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.

Newswise: Study: Artificial Intelligence May Predict Heart Attacks
Released: 1-May-2023 5:30 PM EDT
Study: Artificial Intelligence May Predict Heart Attacks
Cedars-Sinai

What if your physician could predict if—or when—you might experience a heart attack, cardiac arrest or another heart-related problem?

   
Released: 1-May-2023 2:35 PM EDT
Bacteria could make salmon healthier
Norwegian University of Science and Technology (NTNU)

Researchers, including from NTNU, are breeding bacteria-free fish fry. This pursuit is more important than you might think. The researchers have studied how bacteria affect the growth, genes and mucous membranes of the fish.

Newswise: FAU and Insightec Partner to Use Focused Ultrasound to Treat Neurological Disorders
Released: 1-May-2023 8:30 AM EDT
FAU and Insightec Partner to Use Focused Ultrasound to Treat Neurological Disorders
Florida Atlantic University

This agreement will enable FAU and Insightec to collaborate to advance scientific knowledge about the use of focused ultrasound to treat brain diseases, including Parkinson’s disease and Alzheimer’s disease. By harnessing acoustic energy, Insightec’s innovative technology uses focused ultrasound to treat diseases in different ways.

Released: 28-Apr-2023 2:40 PM EDT
Mushrooms and their post-rain, electrical conversations
Tohoku University

Scientists have been studying the possibility of electrical signal transfer between mushrooms and across trees via the mycelial networks. It is thought that fungi generate electrical signals in response to external stimuli and use these signals to communicate with each other, coordinating growth and other behavior.

Released: 28-Apr-2023 1:10 PM EDT
Digital Health Initiative Research Could Lead to More Reliable Health Apps
University of Utah Health

Seven University of Utah Health projects have received seed grants that could promote the development and use of more scientifically based digital health applications in daily health care.

Released: 27-Apr-2023 6:20 PM EDT
How can we fight blood cancer more effectively?
ETH Zürich

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells. These plasma cells are a special type of white blood cells that play an important role in the immune system by producing essential antibodies in the bone marrow and lymph nodes.

Newswise:Video Embedded scientists-slow-aging-by-engineering-longevity-in-cells
VIDEO
24-Apr-2023 9:00 PM EDT
Scientists Slow Aging by Engineering Longevity in Cells
University of California San Diego

Researchers have developed a biosynthetic “clock” that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.

   
Released: 26-Apr-2023 2:00 PM EDT
What’s Eating at You? A New Pill Regulates Appetite Through Electrical Stimulation of the Gut
NYU Tandon School of Engineering

Developed by a research team from NYU Tandon School of Engineering and the Massachusetts Institute of Technology (MIT), a new electrical “pill”, dubbed FLASH, delivers electrical impulses to the stomach lining once it's swallowed and may be able to regulate people’s appetites without any drugs or invasive medical procedures. This targeted stimulation triggers the brain to modulate gut hormones related to hunger.

   
Released: 26-Apr-2023 12:00 PM EDT
Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease
World Journal of Stem Cells

Allogeneic hematopoietic stem cell transplantation is a deterministic curative procedure for various hematologic disorders and congenital immunodeficiency. Despite its increased use, the mortality rate for patients undergoing this procedure

Released: 26-Apr-2023 12:00 PM EDT
Role of brahma-related gene 1/brahma-associated factor subunits in neural stem/progenitor cells and related neural developmental disorders
World Journal of Stem Cells

Different fates of neural stem/progenitor cells (NSPCs) and their progeny are determined by the gene regulatory network, where a chromatin-remodeling complex affects synergy with other regulators. Here, we review recent research progress in

Released: 26-Apr-2023 12:00 PM EDT
Current status and prospects of basic research and clinical application of mesenchymal stem cells in acute respiratory distress syndrome
World Journal of Stem Cells

Acute respiratory distress syndrome (ARDS) is a common and clinically devastating disease that causes respiratory failure. Morbidity and mortality of patients in intensive care units are stubbornly high, and various complications severely a

Released: 26-Apr-2023 12:00 PM EDT
Banking of perinatal mesenchymal stem/stromal cells for stem cell-based personalized medicine over lifetime: Matters arising
World Journal of Stem Cells

Mesenchymal stromal/stem cells (MSCs) are currently applied in regenerative medicine and tissue engineering. Numerous clinical studies have indicated that MSCs from different tissue sources can provide therapeutic benefits for patients. MSC

Released: 26-Apr-2023 12:00 PM EDT
Extracellular vesicles: Emerged as a promising strategy for regenerative medicine
World Journal of Stem Cells

Cell transplantation therapy has certain limitations including immune rejection and limited cell viability, which seriously hinder the transformation of stem cell-based tissue regeneration into clinical practice. Extracellular vesicles (EVs

Released: 26-Apr-2023 12:00 PM EDT
Obesity and cancer stem cells: Roles in cancer initiation, progression and therapy resistance
World Journal of Stem Cells

Obesity, the global pandemic since industrialization, is the number one lifestyle-related risk factor for premature death, which increases the incidence and mortality of various diseases and conditions, including cancer. In recent years, th

Released: 26-Apr-2023 12:00 PM EDT
Clinical application prospects and transformation value of dental follicle stem cells in oral and neurological diseases
World Journal of Stem Cells

Since dental pulp stem cells (DPSCs) were first reported, six types of dental SCs (DSCs) have been isolated and identified. DSCs originating from the craniofacial neural crest exhibit dental-like tissue differentiation potential and neuro-e

Released: 26-Apr-2023 12:00 PM EDT
Human pluripotent stem cell-derived β cells: Truly immature islet β cells for type 1 diabetes therapy?
World Journal of Stem Cells

A century has passed since the Nobel Prize winning discovery of insulin, which still remains the mainstay treatment for type 1 diabetes mellitus (T1DM) to this day. True to the words of its discoverer Sir Frederick Banting, “insulin is no

Released: 26-Apr-2023 12:00 PM EDT
Repetitive administration of cultured human CD34+ cells improve adenine-induced kidney injury in mice
World Journal of Stem Cells

BACKGROUNDThere is no established treatment to impede the progression or restore kidney function in human chronic kidney disease (CKD). AIMTo examine the efficacy of cultured human CD34+ cells with enhanced proliferating potential in kidne



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