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Newswise: Conference on Chemical Processes Related to Environmental and Biological Sciences
Released: 29-Aug-2023 7:05 PM EDT
Conference on Chemical Processes Related to Environmental and Biological Sciences
Environmental Molecular Sciences Laboratory - EMSL

The EMSL User Meeting: Visualizing Chemical Processes Across the Environment is planned for Oct. 3-5 at Pacific Northwest National Laboratory.

   
Newswise: Milenkovic gaining biological insights by analyzing data embedded in non-Euclidean spaces
Released: 29-Aug-2023 4:05 PM EDT
Milenkovic gaining biological insights by analyzing data embedded in non-Euclidean spaces
University Of Illinois Grainger College Of Engineering

Olgica Milenkovic’s group has been developing machine learning approaches that can tell revealing new stories about biological phenomena—but her work has very old roots.

Newswise: Neural Network Helps Design Brand New Proteins
24-Aug-2023 3:15 PM EDT
Neural Network Helps Design Brand New Proteins
American Institute of Physics (AIP)

In Journal of Applied Physics, Markus Buehler combines attention neural networks with graph neural networks to better understand and design proteins. The approach couples the strengths of geometric deep learning with those of language models to predict existing protein properties and envision new proteins that nature has not yet devised. Buehler’s model turns numbers, descriptions, tasks, and other elements into symbols for his neural networks to use.

   
28-Aug-2023 7:00 AM EDT
Only Severe COVID Cases Disrupted Oral Microbiomes
Rutgers University-New Brunswick

Bacteria in the mouth mostly survived infection — and that’s a good thing, says a Rutgers researcher.

Newswise: Myocardial infarction, the number one cause of sudden death, may be treated by modulating the immune response
Released: 25-Aug-2023 12:00 AM EDT
Myocardial infarction, the number one cause of sudden death, may be treated by modulating the immune response
National Research Council of Science and Technology

Dr. Yoon Ki Joung and Dr. Juro Lee of the Biomaterials Research Center at the Korea Institute of Science and Technology (KIST), together with Prof. Hun-Jun Park and Dr. Bong-Woo Park of the Catholic University of Korea College of Medicine, have developed a new treatment for myocardial infarction that uses nanovesicles derived from fibroblasts with induced apoptosis to modulate the immune response.

18-Aug-2023 10:50 AM EDT
Scientists discover a previously unknown way cells break down proteins
Harvard Medical School

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they’ve done their job.

Newswise: Combining immunotherapy with KRAS inhibitor eliminates advanced KRAS-mutant pancreatic cancer in preclinical models
22-Aug-2023 5:05 PM EDT
Combining immunotherapy with KRAS inhibitor eliminates advanced KRAS-mutant pancreatic cancer in preclinical models
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

   
Newswise: How bacteria surf cargo through the cell
Released: 22-Aug-2023 2:20 PM EDT
How bacteria surf cargo through the cell
Michigan Medicine - University of Michigan

The University of Michigan researchers found some bacteria ship cellular cargo by “surfing” along proteins called ParA/MinD ATPases

Newswise: Wistar Researchers Discover Potential Target for Gastric Cancers Associated with Epstein-Barr Virus
Released: 22-Aug-2023 12:00 PM EDT
Wistar Researchers Discover Potential Target for Gastric Cancers Associated with Epstein-Barr Virus
Wistar Institute

Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.

Newswise: Time is right to develop a consensus Human Skin Cell Atlas, according to leading dermatology experts
Released: 21-Aug-2023 3:05 PM EDT
Time is right to develop a consensus Human Skin Cell Atlas, according to leading dermatology experts
Elsevier

As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking.

Released: 18-Aug-2023 2:05 PM EDT
Explore the avian world. Read the latest research on Birds here.
Newswise

The discovery that birds evolved from small carnivorous dinosaurs of the Late Jurassic was made possible by recently discovered fossils of theropods such as Tyrannosaurus rex and the smaller velociraptors. In a way, you could say that dinosaurs are still with us and seen tweeting from your own backyard! Below are the latest research headlines in the Birds channel on Newswise.

Newswise: New LJI research has major implications for controlling T cell activity
Released: 18-Aug-2023 1:25 PM EDT
New LJI research has major implications for controlling T cell activity
La Jolla Institute for Immunology

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells.

Released: 18-Aug-2023 10:05 AM EDT
Immunotherapy: Antibody kit to fight tumors
Ludwig-Maximilians-Universität München (Munich)

A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.

Newswise: Looking at the Latest in Life Sciences Discovery and Technology
Released: 18-Aug-2023 8:00 AM EDT
Looking at the Latest in Life Sciences Discovery and Technology
SLAS

The August 2023 issue of SLAS Technology, the open access journal emphasizing scientific and technical advances across the life sciences, is now available.

   
Released: 17-Aug-2023 4:40 PM EDT
The best thing since sliced tissue
Gladstone Institutes

Imagine a few roughly cut slices of bread on a plate. With just those slices, could you picture, in fine detail, the loaf they came from?

   
Released: 17-Aug-2023 12:50 PM EDT
Lesser-known brain cells may be key to staying awake without cost to cognition, health
Washington State University

New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.

   
Newswise: Immune cells present long before infection predict flu symptoms
Released: 17-Aug-2023 12:35 PM EDT
Immune cells present long before infection predict flu symptoms
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital scientists found that immune cells present in individuals long before influenza infection predict whether the illness is symptomatic.

14-Aug-2023 1:05 AM EDT
Schizophrenia Genetic Risk Factor Impairs Mitochondrial Function
Rutgers University-New Brunswick

Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.

Newswise: Physician-Scientist Receives National Cancer Moonshot Award
Released: 16-Aug-2023 12:30 PM EDT
Physician-Scientist Receives National Cancer Moonshot Award
UT Southwestern Medical Center

Todd Aguilera, M.D., Ph.D., Assistant Professor of Radiation Oncology and member of the Experimental Therapeutics Program in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center, has been named one of 11 inaugural Cancer Moonshot Scholars. The national program recognizes a cohort of early-career investigators from underrepresented groups who have been identified as emerging leaders in cancer research and innovation.

Released: 16-Aug-2023 12:15 PM EDT
MD Anderson Research Highlights for August 16, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

   
Newswise: Sweasy Selected as AACI President-Elect
Released: 16-Aug-2023 11:05 AM EDT
Sweasy Selected as AACI President-Elect
Association of American Cancer Institutes (AACI)

Joann B. Sweasy, PhD, has been elected to serve as vice president/president-elect of AACI’s Board of Directors. Three new board members were also chosen: Edward Chu, MD, MMS; Raymond N. DuBois, MD, PhD; and Yolanda Sanchez, PhD.

Released: 16-Aug-2023 10:00 AM EDT
ASBMB names 2024 award winners
American Society for Biochemistry and Molecular Biology (ASBMB)

ASBMB names 2024 award winners, who will present at #DiscoverBMB in March in San Antonio.

   
Newswise: Decoding how molecules
Released: 15-Aug-2023 4:45 PM EDT
Decoding how molecules "talk" to each other to develop new nanotechnologies
University of Montreal

Two molecular languages at the origin of life have been successfully recreated and mathematically validated, thanks to pioneering work by Canadian scientists at Université de Montréal.

Released: 15-Aug-2023 12:50 PM EDT
Weaker transcription factors are better when they work together
Rice University

Bioengineers can tailor the genomes of cells to create “cellular therapies” that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch on bioengineered genes without occasionally turning on some of the cell’s naturally occurring genes.

   
Newswise: Genetically engineered vesicles target cancer cells more effectively
Released: 15-Aug-2023 9:35 AM EDT
Genetically engineered vesicles target cancer cells more effectively
Binghamton University, State University of New York

Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.

   
Newswise: UTSW finds potential key to predict immunotherapy toxicity
Released: 14-Aug-2023 11:50 AM EDT
UTSW finds potential key to predict immunotherapy toxicity
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center have identified a novel parameter of T cells that could help oncologists anticipate which patients would be most likely to develop immunotherapy toxicity. The findings, published in the Journal for ImmunoTherapy of Cancer, could lead to improved treatments for a variety of cancers.

Newswise: IU researchers uncover mysteries behind immune response to hemophilia A treatment
Released: 14-Aug-2023 11:25 AM EDT
IU researchers uncover mysteries behind immune response to hemophilia A treatment
Indiana University

Patients with the genetic disorder hemophilia A receive factor VIII protein replacement treatments to replenish this clotting protein in their blood, thus preventing dangerous bleeding. Unfortunately, about 30 percent of these patients develop antibodies against the treatment and until now, despite more than 80 years of clinical experience with this complication, little has been known about its mechanism.

Newswise: Neutrons seek to stop cancer from hijacking a metabolic highway
Released: 14-Aug-2023 11:20 AM EDT
Neutrons seek to stop cancer from hijacking a metabolic highway
Oak Ridge National Laboratory

Researchers at Oak Ridge National Laboratory used neutrons and x-rays to draw a roadmap of every atom, chemical bond and electrical charge inside a key metabolic pathway in the body that cancer cells hijack and dramatically overuse to reproduce. The study essentially paves the way for developing new drugs that act as roadblocks that cut off the supply of vital resources to cancer cells. The drugs would be designed to target highly aggressive tumor-forming cancers that too often become terminal such as lung, colon, breast, pancreatic and prostate cancers.

   
Released: 14-Aug-2023 10:55 AM EDT
Study brings insight to kidney cancer with gene mutation
Michigan Medicine - University of Michigan

A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

Newswise: Natural or Not? Scientists Aid in Quest to Identify Genetically Engineered Organisms
Released: 14-Aug-2023 10:15 AM EDT
Natural or Not? Scientists Aid in Quest to Identify Genetically Engineered Organisms
Lawrence Berkeley National Laboratory

Ever since gene editing became feasible, researchers and health officials have sought tools that can quickly and reliably distinguish genetically modified organisms from those that are naturally occurring. Now, such tools exist.

Released: 14-Aug-2023 6:00 AM EDT
Tecnología Innovadora en El Tratamiento Del Cáncer De Cabeza Y Cuello
Mayo Clinic

En todo el mundo, el virus del papiloma humano (VPH) es responsable de una gran proporción de los casos de cáncer de cabeza y cuello, según informa la Organización Mundial de la Salud.

Released: 11-Aug-2023 4:50 PM EDT
Tecnologia Inovadora Trata Cânceres De Cabeça E PescoçO
Mayo Clinic

No mundo todo, o papilomavírus humano (HPV) é responsável por grande parte dos cânceres de cabeça e pescoço, de acordo com a Organização Mundial da Saúde.

Released: 11-Aug-2023 4:30 PM EDT
Research raises hopes for new treatment of fusion-driven cancer
Aarhus University

A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These fusion-driven cancers are caused by an error in cell division that creates a fusion of different genes. This fusion causes the cancer and drives the uncontrolled cell growth.

Released: 11-Aug-2023 12:50 PM EDT
Variable patient responses to SARS-CoV-2 infection are mimicked in genetically diverse mice
Jackson Laboratory

Researchers at The Jackson Laboratory have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection.

   
Released: 10-Aug-2023 10:40 AM EDT
Research team makes surprising discovery of low-noise genes
Virginia Tech

While engaging in cell division research, Silke Hauf and members of her lab made a surprisingly quiet discovery. When cells express RNA, there are always some fluctuations, or noise, in how much RNA is produced. Hauf’s group found several genes whose noise dips below a previously established minimum threshold, known as the noise floor, during expression “We have solid data for this phenomenon,” said Hauf, associate professor in the Department of Biological Sciences at Virginia Tech.

Newswise: Gene therapy hope for children with kidney disease
Released: 10-Aug-2023 8:05 AM EDT
Gene therapy hope for children with kidney disease
University of Bristol

Researchers at the University of Bristol have made a remarkable step forward in finding a potential cure for a type of childhood kidney disease.

Newswise: Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease
Released: 9-Aug-2023 4:05 PM EDT
Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease
University of California San Diego

Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.

Released: 9-Aug-2023 11:05 AM EDT
Tubular tissue advance could pave way for lab-grown blood vessels
University of Edinburgh

Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.

   
Newswise: New Chief of Pediatric Bone Marrow Transplantation and Cellular Therapies Named to New Jersey’s Only NCI-designated Comprehensive Cancer Center
Released: 9-Aug-2023 10:15 AM EDT
New Chief of Pediatric Bone Marrow Transplantation and Cellular Therapies Named to New Jersey’s Only NCI-designated Comprehensive Cancer Center
Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey and RWJBarnabas Health have appointed Niketa C. Shah, MD, as chief of Pediatric Bone Marrow Transplantation and Cellular Therapies at New Jersey’s leading cancer program.

Released: 8-Aug-2023 3:05 PM EDT
Mind what you eat and drink. Food and Water Safety stories for media.
Newswise

The latest headlines from the Food and Water Safety channel on Newswise.

       
Newswise: Chulalongkorn’s Faculty of Pharmaceutical Sciences Presents Plant-Based Biopharmaceutical Research to Combat Cancer Cells in Lab Animals
Released: 8-Aug-2023 8:55 AM EDT
Chulalongkorn’s Faculty of Pharmaceutical Sciences Presents Plant-Based Biopharmaceutical Research to Combat Cancer Cells in Lab Animals
Chulalongkorn University

For the first time in Thailand, lecturers at Chulalongkorn University’s Faculty of Pharmaceutical Sciences have successfully developed antibody from tobacco plants with inhibitory effects on the growth of cancer cells in laboratory animals. This signals hope for access to effective cancer medication and treatment at a lower cost.

   
Newswise: Team discovers broken ‘brake' of cancer mutation machine
Released: 7-Aug-2023 11:45 AM EDT
Team discovers broken ‘brake' of cancer mutation machine
UT Southwestern Medical Center

Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical Center researchers discovered. The findings, published in Cancer Cell, could lead to new interventions that thwart this process in prostate and other cancer types, making them far easier to treat.

Released: 3-Aug-2023 5:45 PM EDT
Study finds a surprising new role for a major immune regulator
Massachusetts Institute of Technology (MIT)

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

Newswise: New Insights Into How RNA Modification Promotes Pancreatic Cancer
Released: 3-Aug-2023 12:05 PM EDT
New Insights Into How RNA Modification Promotes Pancreatic Cancer
Chinese Academy of Sciences

In a breakthrough study, researchers have revealed a new understanding of the role played by RNA modification in the progression of pancreatic ductal adenocarcinoma (PDAC), a leading cause of cancer-related deaths. The research pinpoints how the long non-coding RNA (lncRNA), LINC00901, and its N6-methyladenosine (m6A) modification, contribute to the disease, offering a potential new avenue for therapeutic interventions.

Newswise: NUS study: A patchwork of Wnt signalling ligands and receptors pattern the colours on the wings of butterflies
Released: 3-Aug-2023 8:50 AM EDT
NUS study: A patchwork of Wnt signalling ligands and receptors pattern the colours on the wings of butterflies
National University of Singapore (NUS)

Some of the open research questions revolving Wnt signalling revolve around the extraordinary complexity in the number of Wnt pathway members, functioning both inside, outside, and at the surface of cells, and how different outputs of the pathway are achieved via the use of specific members. A team of scientists, led by Professor Antónia Monteiro from the Department of Biological Sciences at the National University of Singapore’s Faculty of Science, has uncovered some of this complexity by using butterfly wings as a model system. Butterfly wings function as a large two-dimensional canvas of cells that talk to each other during development to pattern exquisite and detailed colour patterns.

Released: 2-Aug-2023 1:20 PM EDT
We’re closer to engineering blood vessels
University of Melbourne

University of Melbourne researchers have developed a fast, inexpensive and scalable method for engineering blood vessels from natural tissue.

   
Newswise:Video Embedded novel-molecules-burst-virus-bubbles-to-fight-infection
VIDEO
Released: 2-Aug-2023 12:45 PM EDT
Novel molecules fight viruses by bursting their bubble-like membranes
New York University

Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers?

   
Released: 2-Aug-2023 12:00 PM EDT
MD Anderson Research Highlights for August 2, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel biomarker that may predict the aggressiveness of pancreatic cancer precursors, insights into the structure and function of a breast and ovarian cancer susceptibility gene, a new approach to overcoming treatment resistance in ovarian cancer, distinguishing features of young-onset rectal cancer, a biomarker and potential target for metastatic lung cancer, machine learning models to better predict outcomes of patients with mantle cell lymphoma (MCL), and a promising therapy for patients with relapsed/refractory MCL.

Released: 2-Aug-2023 10:40 AM EDT
New study shows that WATS3D increases diagnostic yield of dysplasia in Barrett's esophagus, regardless of segment length
CDx Diagnostics

CDx Diagnostics, Inc., developer of the WATS3D AI Platform for the detection and surveillance of Barrett's esophagus (BE) and dysplasia, reported positive data in a recently published study, Benefit of Adjunctive Wide Area Transepithelial Sampling with 3- Dimensional Computer-Assisted Analysis Plus Forceps Biopsy Based on Barrett's Esophagus Segment Length, in the American Society for Gastrointestinal Endoscopy (ASGE) journal GIE (Gastrointestinal Endoscopy).



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