Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland
PreprintsValeria Scagliotti, Maria Lillina Vignola, Thea L Willis, Mark Howard, Eugenia Marinelli, Carles Gaston-Massuet, Cynthia Lilian Andoniadou, Marika Charalambous
Feature Channels: Stem Cells
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Released: 2-Nov-2022 12:00 PM EDT
Released: 2-Nov-2022 9:55 AM EDT
New 3D model shows how cadmium exposure may affect heart development
National Institute of Environmental Health Sciences (NIEHS)Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead to congenital heart disease.
Released: 1-Nov-2022 3:00 PM EDT
Researchers Identify a Regulator of Breast Cancer Development
UT Southwestern Medical CenterUT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.
Released: 1-Nov-2022 1:05 PM EDT
骨髓移植的五大关键进步
Mayo Clinic罗切斯特 ， 明尼苏达州 - 六十 前 ， ， 血液 骨髓 移植 只 种 尝试 救治血癌 试验性 疗法 ， 经过 年 发展 ， ， 如今 已然 种 重要 抗癌 手段。 当前 ， 医疗 医疗 医疗
Released: 1-Nov-2022 1:05 PM EDT
Cinco AvançOs Fundamentais Nos Transplantes De Medula óSsea
Mayo ClinicNas seis décadas em que o transplante de sangue e medula tem sido usado para tratar pacientes com câncer no sangue, esse tratamento experimental tornou-se uma ferramenta vital de combate ao câncer. A Mayo Clinic, em Rochester, Minnesota, está celebrando a marca de 10 mil transplantes sanguíneos e de medula usados para o tratamento de cânceres sanguíneos e de doenças relacionadas.
Released: 1-Nov-2022 1:00 PM EDT
خمسة تطورات رئيسية في عمليات زراعة نخاع العظم
Mayo Clinicمدينة روتشستر، ولاية مينيسوتا. - على مدار الستة عقود الماضية منذ بداية استخدام عمليات زراعة الدم والنخاع لعلاج المرضى المصابين بسرطان الدم، أصبح هذا العلاج التجريبي أداة حيوية لمكافحة السرطان. تحتفل مايو كلينك في مدينة روتشستر بولاية مينيسوتا بإجراء 10,000 عملية زراعة دم ونخاع لعلاج سرطانات الدم والاضطرابات ذات الصلة.
Released: 1-Nov-2022 12:00 PM EDT
Cinco Avances Clave en Los Trasplantes De MéDula óSea
Mayo ClinicEn las seis décadas posteriores a que se comience a utilizar el trasplante de médula para tratar a pacientes con distintos tipos de cáncer de la sangre, este tratamiento, que en un principio fue experimental, se ha vuelto una herramienta vital para la lucha contra el cáncer. Mayo Clinic de Rochester (Minnesota) celebra el trasplante de sangre y médula ósea número 10 000 utilizado en el tratamiento de distintos tipos de cáncer de la sangre y trastornos relacionados.
Released: 1-Nov-2022 12:00 PM EDT
The cell developmental atlas of human embryonic temporomandibular joint
PreprintsQianqi Zhu, Miaoying Tan, Chengniu Wang, Yufei Chen, Chenfei Wang, Junqi Zhang, Yijun Gu, Yuqi Guo, Jianpeng Han, Lei Li, Rongrong Jiang, Xudong Fan, Huimin Xie, Liang Wang,
Released: 1-Nov-2022 12:00 PM EDT
Engineering of Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilisation of Bioemulsions Enabling Adherent Cell Expansion
PreprintsAlexandra Chrysanthou, Minerva Bosch-Fortea, Julien Gautrot
Released: 1-Nov-2022 12:00 PM EDT
Cut homeodomain transcription factor is a novel regulator of cortical glia morphogenesis and niche maintenance around neural stem cells
PreprintsVaishali Yadav, Papri Das, RamKrishna Mishra, Richa Arya
Released: 1-Nov-2022 12:00 PM EDT
Understanding the impact of bioactive coating materials for human mesenchymal stem cells and implications for manufacturing
PreprintsPedro Silva Couto, Sam A. Molina, Denis O’Sullivan, Liam O'Neill, Alexander M. Lyness, Qasim Rafiq
Released: 1-Nov-2022 12:00 PM EDT
A TDP-43 acetylation-mimic mutation that disrupts RNA-binding drives FTLD-like neurodegeneration in a mouse model of sporadic TDP-43 proteinopathy
PreprintsJulie Necarsulmer, Jeremy Simon, Baggio Evangelista, YouJun Chen, Xu Tian, Sara Nafees, Ariana Marquez Gonzalez, Ping Wang, Deepa Ajit, Viktoriya Nikolova, Kathryn Harper, Jennifer Ezzell, Adriana Beltran, Sheryl Moy,
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of PRTG in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of CDKN1A in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of CIART in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of COL19A1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of B3GALNT2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of CERKL in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells
PreprintsYuka Sakata, Keren Cheng, Michinori Mayama, Yasunari Seita, Andrea J Detlefsen, Clementina A Mesaros, Trevor M Penning, Kyosuke Shishikura, Wenli Yang, Richard J Auchus, Jerome F Strauss, Kotaro Sasaki
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of ZNF385D in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of EYA in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of ADGRV1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Differential expression of HOXC9 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 1-Nov-2022 12:00 PM EDT
Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2
PreprintsSang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S Tibbetts
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of LGALSL in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of HOXB6 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of UGGT1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of SEMA5A in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of USP9Y in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of EMC10 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of DST in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of XDH in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of HEBP2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of GPR160 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of PPM1K in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
miR-223 Plays A Critical Role in Obesogen-Enhanced Adipogenesis in Mesenchymal Stem Cells and in Transgenerational Obesity
PreprintsRichard C Chang, Erika M. Joloya, Zhuorui Li, Bassem M Shoucri, Toshi Shioda, Bruce Blumberg
Released: 28-Oct-2022 7:20 PM EDT
Cedars-Sinai Awarded $8 Million to Launch New Stem Cell Clinic
Cedars-SinaiCedars-Sinai has been awarded a five-year, $8 million grant from California’s stem cell agency to launch an innovative new clinic that will expand patients’ access to stem cell and gene therapies, increase research and training in regenerative medicine, foster greater collaboration with eight similar clinics across the state and help educate the public about stem cell and related therapies.
Released: 28-Oct-2022 12:20 PM EDT
Stem Cell Grafts and Rehabilitation Combined Boost Spinal Cord Injury Results
University of California San DiegoIn animal models, UC San Diego researchers found that intensive physical therapy in tandem with implanted neural stem cells increased tissue growth, repair and functionality in spinal cord injuries more than those treatments alone
Released: 28-Oct-2022 12:00 PM EDT
Advanced glycation end products inhibit the osteogenic differentiation potential of adipose‐derived stem cells in mice through autophagy
PreprintsTing Fu, Fangzhi Lou, Qiang Zhu, Shuyu Cai, Shuanglin Peng, Jingang Xiao
Released: 28-Oct-2022 12:00 PM EDT
Transcriptional regulation profiling reveals PPARA-mediated fatty acid oxidation as a novel therapeutic target in phospholamban R14del cardiomyopathy
PreprintsMagdalena Harakalova, Jiayi Pei, Renee Maas, Karen Gaar-Humphreys, Johannes Gho, Emilia Nagyova, Christian Snijders Blok, Iris van Adrichem, René van Es, Shahrzad Sepehrkhouy, Dries Feyen, Noortje Van Den Dungen, Nico Lansu, Jorg Cal
Released: 28-Oct-2022 12:00 PM EDT
Protein aggregation and calcium dysregulation are the earliest hallmarks of synucleinopathy in human midbrain dopaminergic neurons
PreprintsGurvir S Virdi, Minee Liane Choi, James R Evans, Zhi Yao, Dilan Athauda, Stephanie Strohbuecker, Anna I Wernick, Haya Alrashidi, Daniela Melandri, Jimena Perez-Lloret, Plamena R Stroh, Sergiy Sylantyev, Simon Eaton, Simon Heales,
Released: 28-Oct-2022 12:00 PM EDT
Human T2D associated gene IMP2/IGF2BP2 promotes the commitment of mesenchymal stem cells into adipogenic lineage
PreprintsLaura Regue, William Wang, Fei Ji, Joseph Avruch, Hua Wang, Ning Dai
Released: 28-Oct-2022 12:00 PM EDT
Achieving permanent transplant tolerance via reverse chimeras in orthotopic liver transplantation
PreprintsGaofeng Tang, Huibo Zhao, Guoyong Chen
Released: 28-Oct-2022 12:00 PM EDT
High levels of m6A methylation and histone acetylation modification patterns contribute to the survival of LUAD patients
PreprintsLiguo Jia, Zhenzhen Gao, Jing Chen
Released: 28-Oct-2022 12:00 PM EDT
Assessment Of 3D Printed Polycaprolactone, Hydroxyapatite Nanoparticles and Polyethylene Glycol Diacrylate Scaffolds for Bone Regeneration
PreprintsAna Catarina Sousa, Sara Biscaia, Rui Alvites, Mariana Branquinho, Bruna Lopes, Patrícia Sousa, Joana Valente, Margarida Franco, José Domingos Santos, Carla Mendonça, Luís Atayde, Nuno Alves, Ana Colette Maurício
Released: 28-Oct-2022 12:00 PM EDT
The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited
Preprints
Released: 28-Oct-2022 12:00 PM EDT
Extracellular vesicles promote lipid raft formation in human microglia through TLR4, P2X4R, and αVβ3/αVβ5 signaling pathways
PreprintsAugustas Pivoriūnas
Released: 28-Oct-2022 12:00 PM EDT
Extract of Plastrum Testudinis through miR-214 mediated Wnt/β-catenin signaling stimulating bone formation
PreprintsQing Lin, Yumei Yang, Xiaoyun Li, Haoyu Wang, Yan Cui, Panpan Wang, Xiaofeng Zhu, Li Yang, Ronghua Zhang
Released: 28-Oct-2022 12:00 PM EDT
Temporary knockdown of p53 during focal limb irradiation increases the development of sarcomas
PreprintsAndrea R. Daniel, Chang-Lung Lee, Chang Su, Nerissa T. Williams, Zhiguo Li, Jianguo Huang, Omar Lopez, Lixia Luo, Yan Ma, Lorraine De Silva Campos, Sara R. Selitsky, Jennifer L. Modliszewski, Siyao Liu, Yvonne M. Mowery,
Released: 28-Oct-2022 12:00 PM EDT
Induction of telomerase in p21-positive cells counteracts capillaries rarefaction in aging mice lung
PreprintsLarissa Lipskaia, Marielle Bréau, Christelle Cayrou, Dmitri Churikov, Laura Braud, Charles Fouillade, Sandra Curras-Alonso, Serge Bauwens, Frederic Jourquin, Frederic Fiore, Rémy Castellano, Emmanuelle Josselin, Carlota Sánchez-Ferrer,
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