Researchers from the University of Toledo (Ohio) College of Medicine and Life Sciences have discovered more than 12,000 different types of noncoding RNA (circRNAs) in the kidney tissue of rats. This type of genetic material, previously thought to have no function, may play a significant role in regulating blood pressure in heart and kidney disease.
No disorder appears to kill more people than atherosclerosis, and hopeful experimental treatments with "good cholesterols" have failed. New research reapproaches them with carefully designed cholesterols in an organ-on-a-chip in highly reproducible experiments.
Researchers have shown, for the first time, that reduced dietary potassium promotes elevated aortic stiffness in a mouse model. Such arterial stiffness in humans is predictive of heart disease and death from heart disease, and it represents an important health problem for the nation.
A new, inexpensive urine test accurately identifies patients at risk for kidney damage after open heart surgery, allowing for corrective action before permanent injury occurs.
The University of Illinois at Chicago, the University of Chicago Medicine, and Northwestern Memorial Hospital are part of a newly-formed national network that will collaborate to conduct clinical trials designed to improve the outcomes for patients with neurologic, cardiac, respiratory, hematologic and trauma-related emergency events.
A new review of more than 500 studies examines the environmental and physiological causes of physical inactivity and the role it plays in the development of chronic disease. The article is published in Physiological Reviews.
Alain Tanbe, M.D., a fellowship-trained vascular surgeon at The Vascular Center at Mercy Medical Center, recently utilized the FDA-approved LUTONIX® 035 Drug Coated Balloon (DCB) Catheter 035 to treat arteriovenous (AV) fistula, Paul R. Lucas, M.D., Director of Mercy’s Vascular Center, announced.
Individualized medicine — the concept of matching medical care precisely to each patient’s genes, lifestyle and environment is no longer just a theory. Experts in individualized medicine — also known as personalized or precision medicine — will be in Rochester Oct. 9-10, presenting the latest ways to apply precision medicine to all patients. They are available for interviews on groundbreaking discoveries at Individualizing Medicine 2017: Advancing Care Through Genomics, which will be held at Mayo Civic Center.
A review of the weight gain risks and challenges faced by women in midlife has led Mayo Clinic researchers to a series of recommendations for this patient population. The findings are published in this month's edition of Mayo Clinic Proceedings.
Advances in trauma care, medical technology and management of severe illnesses have led to the relatively quick adoption of the open abdomen technique for patients with many life-threatening medical and surgical diagnoses.
The University of Louisville has received one of its largest grants for medical research in the school’s 219-year history, a $13.8 million award from the National Institutes of Health to study a promising new type of adult cardiac stem cell that has the potential to treat heart failure.
Atrial fibrillation is the most prevalent form of cardiac arrhythmia, affecting up to 6 million people in the U.S. alone. Common treatments for severe forms of the erratic beating phenomenon are controversial, and guided by detection methods that are not yet standardized or fully refined. But research from a group of cross-disciplinary scientists, published this week in the journal Chaos, offers a computational approach to understanding the important factors involved in measuring cardiac excitation waves.
Magnetic resonance imaging appears to be safe for patients with cardiac implantable electronic devices, even for chest imaging, according to a new study by researchers from the Intermountain Medical Center Heart Institute.
UNC School of Medicine cardiologist Anil Gehi, MD, will use a $1.7 million grant from the Bristol-Myers Squibb Foundation to further innovate a care model, launched in 2015, that reduced hospitalizations for patients with atrial fibrillation (Afib) presenting in the emergency room by more than 30 percentage points in its first year.
A North Dakota State University research team led by Dr. Yagna Jarajapu in pharmaceutical sciences has been awarded more than $1.3 million in a five-year grant from the National Institutes of Health for research to combat the negative impact of diabetes on blood vessels.
Early research results suggest scientists might be on to a way to preserve heart function after heart attacks or for people with inherited heart defects called congenital cardiomyopathies. Researchers at the Cincinnati Children’s Heart Institute report Sept. 28 in Nature Communications that after simulating heart injury in laboratory mouse models, they stopped or slowed cardiac fibrosis, organ enlargement and preserved heart function by blocking a well-known molecular pathway.
Women with heart disease typically receive less complete surgical revascularization with arterial grafts than men do, but not because of gender bias. Instead, factors such as delayed diagnosis of coronary artery disease (CAD) in women may contribute to the differences in treatment.
DETROIT – A new evaluation to determine whether emergency room patients with chest pain can go home and follow up with their doctor proved 100% safe while shaving nearly a day off their visit and $6500 off their bill.
Co-Chair of Consensus Committee Advising Trump Administration on Global Health Outlines How the United States Can Bolster Its Global Health Efforts
When expectant mothers have elevated blood pressure during pregnancy, it may raise their children’s risk of developing childhood obesity, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The Cardiovascular Research Foundation (CRF) has announced the press conference schedule for late-breaking trials and first report investigations that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2017 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2 in Denver, Colorado.
NewYork-Presbyterian Morgan Stanley Children’s Hospital has opened The Vivian and Seymour Milstein Family Infant Cardiac Unit. The new, state-of-the-art, 17-bed unit is solely dedicated to infant cardiac care (0-3 months old) and is the first of its kind in the United States.
To advance ongoing and innovative research in women’s health, a $1 million prize will be awarded to a team of top scientists at the inaugural Magee 9-90™ Research Summit, taking place Oct. 8-10, 2018, in Pittsburgh. The international summit will bring together the world’s leading women’s health research scientists and thought leaders to establish a national agenda in women’s reproductive sciences and health research, and will ignite the next generation of scientific leaders.
Scientists at the UNC School of Medicine and elsewhere are exploring ways to reprogram scar tissue cells into healthy heart muscle cells, and now UNC researchers have published the first scientific paper to compare in great detail the two leading reprogramming techniques.
A new report shows how microsystems can be used to understand processes in heart tissue in detail and to test newly developed compounds applied in the treatment of cardiac diseases.
Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart failure in a large animal model, Mount Sinai researchers report. This is the first study using a novel vector for gene therapy to improve heart function in non-ischemic heart failure.
Researchers at the University of Georgia’s Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments.
One of the few large studies to report long-term outcomes in cardiac patients treated in childhood with extracorporeal membrane oxygenation (ECMO) has found overall favorable outcomes among survivors, as reported by families. ECMO provides short-term breathing and heart support for critically ill children while doctors treat the underlying illness.
More than 100 physicians from UC San Diego Health were named “Top Docs” in the annual San Diego Magazine “Physicians of Exceptional Excellence” annual survey. These physicians represent 45 diverse specialties, from infectious disease, surgery and oncology to obstetrics, cardiology and emergency medicine.
The Prospective Urban Rural Epidemiology (PURE) study, led by the Population Health Research Institute of McMaster University and Hamilton Health Sciences, shows any activity is good for people to meet the current guideline of 30 minutes of activity a day, or 150 minutes a week to raise the heart rate.
Outdoor air pollution may increase the risk of chronic kidney disease and contribute to kidney failure, Washington University School of Medicine in St. Louis and the Veterans Affairs (VA) St. Louis Health Care System. Scientists culled national VA databases to evaluate the effects of air pollution and kidney disease on nearly 2.5 million people over a period of 8.5 years, beginning in 2004. The scientists compared VA data on kidney function to air-quality levels collected by the Environmental Protection Agency (EPA) as well as the National Aeronautics and Space Administration (NASA). The study is published Sept. 21 in the Journal of the American Society of Nephrology.
Alabama Adult Congenital Heart Disease Director Mark Cribbs, M.D.In the last decade, the number of adults living with congenital heart disease began exceeding the number of children living with congenital heart disease, even as treatments improved. That means more and more people are in need of adult care. “The transition from pediatric to adult care can be difficult to navigate,” said Alabama Adult Congenital Heart Disease Director Mark Cribbs, M.
A new UCLA study found that healthy nonsmokers experienced increased adrenaline levels in their heart after one electronic cigarette (e-cigarette) with nicotine. The findings are published in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.
Researchers at Joslin Diabetes Center have identified an unexpected natural protective factor against chronic inflammation that drives cardiovascular disease in type 2 diabetes.
In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene.
University Health Network (UHN) announced today that The Peter and Melanie Munk Charitable Foundation is increasing its support to the Peter Munk Cardiac Centre (PMCC) with a transformative gift of $100 million.
Working in mice, researchers at Washington University School of Medicine in St. Louis have identified a way to convert white fat, which stores calories, into brown fat that burns them.
Today in Philadelphia, Penn Medicine has deepened its commitment to the American Heart Association by announcing a three-year pledge as the market’s first ever Life is Why sponsor. The American Heart Association and Penn Medicine are dedicated to creating a culture of health in Philadelphia by providing local and regional communities with education and resources that advance health and wellness.
A recent report from the National Heart, Lung and Blood Institute Working Group on the role of microbiota in blood pressure regulation underscored “there is a critical need to discover novel and innovative ways to address the blood pressure control issue.”
A new paper-based sensor patch developed by researchers at Binghamton University, State University of New York could allow diabetics to effectively measure glucose levels during exercise.
Teva and Mount Sinai Health System pursue new models to reduce cost and complexity of care
Among patients who undergo childhood heart surgery for the severe birth defect single-ventricle disease, two-thirds of survivors require a surgical or catheter-based procedure within 20 years. Pediatric cardiology researchers note that doctors should counsel families about the likelihood of re-interventions.
The incidence of heart disease is on the rise, and new therapeutic strategies are needed.
City Health Works and Mount Sinai St. Luke’s (MSSL) are collaborating on a one-year pilot, launched in mid-July, to reduce hospital readmissions for patients with congestive heart failure.
A Cedars-Sinai interventional cardiologist has performed the first minimally invasive procedure using a device that could spare patients with a common congenital heart defect from undergoing multiple open-heart surgeries. B-Roll Video Available
Did you know that more than 3 million Americans are affected by atrial fibrillation? Atrial fibrillation, which is also referred to as AF or AFib, is the most common irregular or abnormal heart rhythm disorder. It decreases the heart’s pumping ability and can make the heart work less efficiently. In addition, patients must be aware that AFib can lead to potentially life-threatening problems such as blood clots and a higher risk of stroke.
Saint Louis University scientist Mee-Ngan F. Yap, Ph.D.,has uncovered the way a bacterial ribosome moves from an inactive to an active form, and how that "wake up call" is key to its survival.
The Cardiovascular Research Foundation (CRF) has announced the 12 late-breaking trials and 16 first report investigations that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2017 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2, 2017 at the Colorado Convention Center in Denver, Colorado.
Clinicians are being warned not to ignore the increased cardiovascular health risks of those who are classed as either ‘healthy obese’ or deemed to be ‘normal weight’ but have metabolic abnormalities such as diabetes.
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