Vanderbilt University Medical Center (VUMC) and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development.
The Cardiovascular Research Foundation (CRF) today announced the appointment and promotion of Juan F. Granada, MD, as the foundation’s President and Chief Executive Officer. Dr. Granada was also appointed to CRF’s Board of Directors. A renowned leader in cardiology, he joined CRF in 2007 and served as Executive Director and Chief Innovation Officer at the CRF Skirball Center for Innovation.
Researchers at the University of Maryland School of Medicine have found that a new, collaborative treatment model for seriously ill heart patients with breathing difficulties results in better care and lower costs.
New research by UT Southwestern cardiologists shows that people of South Asian descent with a family history of coronary heart disease are significantly more likely to have high levels of calcium buildup in their arteries – an indicator of higher risk for heart attacks.
ZOWEEEE!! Kennesaw State University’s Office of Research recorded a big first: 4 DIFFERENT researchers garnered 4 NSF grants over 4 days. “This is a really cool story for us,” said Jonathan McMurry, associate vice president for research. “It was almost surreal, every day a new grant coming in!”
Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end of the chromosome, protecting it from deterioration or fusion with adjacent chromosomes. While there is a length range for classifying a healthy telomere, researchers found, for the first time ever, that people with heart failure have shorter telomeres within the cells that make up the heart muscle (known as cardiomyocytes). A team of researchers from Penn Medicine, in collaboration with the University of Connecticut, published their findings today in the Journal of the American Heart Association, building on a methods paper which was published recently in Nature Protocols.
Sixteen years after the collapse of the World Trade Center towers sent a “cloud” of toxic debris across Lower Manhattan, children living nearby who likely breathed in the ash and fumes are showing early signs of risk for future heart disease.
The grant provides support for an innovative clinical trial that seeks to compare outcomes for young patients with newly diagnosed severe aplastic anemia – comparing the use of unrelated-donor blood and marrow transplant to immune suppression therapy.
Again and again, it’s the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.
A form of the fatty acid-derived bioactive molecule called lipoxin improved heart function after a heart attack, as the lipoxin prompted early activation of the resolving phase of the immune response in mice without altering the acute phase.
A synthetic version of low molecular weight heparin is poised for clinical trials and development as a drug for patients with clotting disorders, and those undergoing procedures such as kidney dialysis, heart bypass surgery, stent implantation, and knee and hip replacement.
The Ted Rogers Centre for Heart Research today announces that Dr. Raymond Kim is its newest scientific lead, guiding efforts at the country’s only clinic devoted to cardiac genomics.
It is estimated that employees spend more than half their day sitting down. A recent study has found that this could lead to serious health problems such as cancer, heart disease and diabetes.
Leading experts in stroke and neurovascular treatment and research to participate in a one day, rapid fire. TED-style stroke conference at Henry Ford Hospital in Detroit, MI.
Two new studies led by researchers at the Johns Hopkins Bloomberg School of Public Health suggest that the bevy of tools available to assess and address childhood adversity and trauma, as well as the interconnected webs of relationships among families and the providers who care for children, are key to healing the effects of these potentially life-altering circumstances.
Free Cholesterol Health Fairs Offered Throughout New York City
Recent outbreaks of Zika virus have revealed that the virus causes brain defects in unborn children. But in a study to be published September 5 in The Journal of Experimental Medicine, researchers from Washington University School of Medicine in St. Louis and the University of California, San Diego report that the virus could eventually be used to target and kill cancer cells in the brain.
Loyola Medicine's solid organ transplant program has reached another major milestone with the successful performance of its first pancreas transplant.
Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes. T2D is also a significant risk factor for coronary heart disease (CHD), but the biological pathways that explain the connection have remained somewhat murky. Now, in a large analysis of genetic data, published on August 28, 2017 in Nature Genetics, a team, led by researchers in the Perelman School of Medicine at the University of Pennsylvania, has first looked into what causes T2D and second clarified how T2D and CHD – the two diseases that are the leading cause of global morbidity and mortality, are linked.
Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects. A report of the study’s findings, published in the August issue of The Journal of Clinical Endocrinology & Metabolism, adds further support for the consistent use of continuous positive airway pressure (CPAP), a machine that increases air pressure in the throat to keep the airway open during sleep.
Changing from scheduled appointments to an "open gym" format can reduce waiting times for cardiac rehabilitation, reports a study in the September/October issue of Journal of Cardiopulmonary Rehabilitation and Prevention. The journal is published by Wolters Kluwer.
Scientists may have found a clue to why people living with HIV have double the likelihood of developing heart disease. The findings, made by researchers at the University of Pittsburgh Center for Vaccine Research and National Institutes of Health, also show that an experimental drug may hold promise as a potential treatment.
Biomedical engineering researchers at Case Western Reserve University are refining more than 15 years of work on an electrical nerve-block implant, focusing their next step on new applications related to treating asthma and heart failure.
Compared to people who live in predominantly white neighborhoods, those who live in predominantly black areas are much less likely to receive CPR or defibrillation from a bystander when their heart suddenly stops beating while they are at home or out in the community.
A scientist at Sanford Research studying lung development and disease in premature babies has received a $2,041,195 grant over five years from the National Institutes of Health’s National Heart, Lung and Blood Institute. Peter Vitiello, Ph.D., will study how molecular pathways contribute to lung development and disease in premature babies.
A new study published in Menopause: The Journal of The North American Menopause Society has found that low-dose hormone therapy may be effective in easing sleep issues in this population.
Federal and state government can alter or hinder state and local activity through a legal mechanism called preemption – when a higher level of government blocks the action of a lower level of government. A new study evaluates whether it could it be used to block taxes on sugar-sweetened beverages.
In humans, going just minutes without oxygen—such as during a heart attack or stroke—can cause devastating damage to the heart. Researchers looking to freshwater turtles to understand the mechanisms that protect them from heart damage after long hibernation periods will present their findings at the Physiological Bioenergetics: Mitochondria from Bench to Bedside conference in San Diego.
Statins are highly effective for preventing heart attacks by reducing low-density lipoprotein or “bad” cholesterol. However, 10 to 20 percent of patients taking statins report muscle-related symptoms including aches, pains and cramps that prevent the use of recommended doses. Patients who have difficulty taking statins have a high risk of cardiovascular events, resulting in higher health care costs. To address these concerns, Mount Sinai researchers are providing approaches to optimize cardiovascular risk reduction for these patients. The findings will be published in Journal of the American College of Cardiology on Monday, August 28, at 2 pm.
In a large, international study led by the Duke Clinical Research Institute and five coordinating centers around the world, an informational campaign aimed at patients, families and physicians led to a 9-percent absolute increase in the use of anticoagulation therapies. The increased drug adherence was accompanied by a small, but notable reduction in the risk of stroke.
A new study shows radiofrequency catheter ablation lowered hospitalization and mortality rates by 47 and 44 percent respectively in patients with atrial fibrillation (AF), a contributing factor to heart failure.
A major international study has found that the combination of two drugs – rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease.
Researchers successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia. In a preclinical study, researchers found that the gene, LeXis, lowered cholesterol and blockages in the arteries, and the treatment appeared to reduce the build-up of fat in liver cells.
Nathan Bryan, Ph.D., one of the world’s leading experts on the critically important role of Nitric Oxide (NO) in the health of many of the body’s organs and systems, said,” understanding the vital effects of bacteria in the mouth is essential for health care providers, although it is not widely understood by the public.” He delivered an invited lecture to attendees of the The American Naturopathic Medical Association 36th Annual Convention and Educational Seminar.
By fleshing out how one signaling receptor contributes to causing obesity through its activity in fatty tissue but not in muscle cells, SBP scientists have zeroed in on an important new avenue of exploration for combating metabolic disease. More than one-third of American adults are considered to be obese, which dramatically increases their risk for developing type 2 diabetes, non-alcoholic fatty liver disease, high blood pressure, and multiple inflammatory conditions.
Biomedical engineering researchers will attack two banes of cardiovascular disease — heart failure after heart attacks and the scourge of resistant high blood pressure — with $4.8 million in National Institutes of Health grants that begin this fall.
Two studies provide additional support for lowering systolic blood pressure to an intensive goal of 120 mmHg – far below the standard guidelines of 140 mmHg – to reduce the risk of heart disease in high-risk patients with hypertension. The new research shows that intensive blood pressure control is well-tolerated by patients and is cost-effective in terms of health-related quality of life and financial costs to the healthcare system, and appears online in NEJM on Aug. 24.
Four University of Utah Health researchers will present their research and clinical trial findings, as well as engage in critical discussions around cardiovascular medicine at the 2017 European Society of Cardiology Congress in Barcelona, Spain.
PinnacleHealth is the first hospital in Pennsylvania and one of the first 10 in the country to introduce new technology shown to help protect patients from the risk of stroke during transcatheter aortic valve replacement (TAVR).
The first new national guidelines since 2004 on identifying and treating high blood pressure in children and adolescents (aged 3-18 years old) have been published by the American Academy of Pediatrics (AAP), which convened a panel of experts to produce the new recommendations. The AAP report, Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents, offers a series of evidence-based recommendations for pediatricians derived from a comprehensive review of nearly 15,000 medical studies published since 2004.
Jersey Shore University Medical Center is first hospital in region to perform cutting-edge surgery; innovative procedure is revolutionizing cardiac and vascular operations, delivering safer and less invasive surgeries
Id genes play surprise role in cardiac development
Diabetes is a tough disease to manage. Oral medications, insulin shots, close monitoring of blood sugar, dietary changes and exercise can all factor into a person’s treatment regimen. Now researchers are exploring a novel, simpler approach: implanting a polymer sponge into fat tissue. Their study has shown that in obese mice with symptoms resembling Type 2 diabetes, the implant reduced weight gain and blood-sugar levels — by getting the fat to “talk” again.
A new Michigan State University study on 240 emergency room patients shows just how much of a role a person’s cholesterol plays, when in a crystallized state, during a heart attack.
Dr. Seth Worley has joined MedStar Heart & Vascular Institute’s Cardiac Electrophysiology Program as a senior consultant. A renowned expert in cardiac resynchronization therapy, Dr. Worley has personally developed tools and techniques designed to facilitate and optimize left ventricular (LV) lead implantation.
A new University of Michigan study finds slightly more than half of heart patients are admitted to the CICU for noncardiac conditions, such as sepsis or renal failure, rather than for a heart condition.
A history of smoking significantly increases the chance that survivors will experience recurrence of a brain aneurysm, according to a University of Michigan study. Researchers say it’s a serious reminder about the importance of smoking cessation, especially for patients who undergo endovascular aneurysm treatment.
A new clinical trial led by investigators at NewYork-Presbyterian, Columbia University Medical Center (CUMC) and Weill Cornell Medicine aims to identify and treat what may be a common underlying cause of recurrent strokes.
Researchers report encouraging preclinical results as they pursue elusive therapies that can repair scarred and poorly functioning heart tissues after cardiac injury. Scientists from the Cincinnati Children’s Heart Institute inhibited a protein that helps regulate the heart’s response to adrenaline, alleviating the disease processes in mouse models and human cardiac cells. Their data publishes Aug. 22 in the Journal of the American College of Cardiology.
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