Newswise — Philadelphia, Pa. (January 8, 2013) – As perceived by both patients and doctors, the cosmetic results after "lumpectomy" for breast cancer differ for African-American versus Caucasian women, suggests a pilot study in the Plastic and Reconstructive Surgery—Global Open®, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS).

Despite similar results on objective assessments, "It appears that there is a difference in the perception of cosmetic outcomes between Caucasian and African-American patients," according to the study led by ASPS Member Surgeon Dr. Robert D. Galiano of Northwestern University Feinberg School of Medicine. They call for further studies using validated assessment tools to help in optimizing breast appearance for women undergoing breast-conserving therapy (BCT).

Study Finds Similar Objective Outcomes By Race… The pilot study included 21 women undergoing BCT for breast cancer: 10 African-American and 11 Caucasian women. Breast-conserving therapy combines lumpectomy or other limited surgery, as an alternative to mastectomy. Surgery is typically followed by radiation therapy to reduce the risk of recurrent breast cancer.

All women underwent detailed, "multimodal" assessments of their cosmetic outcomes. This included objective measurements of breast volume and symmetry, based on three-dimensional photographic analysis.

In addition, a newly developed questionnaire was used for subjective ratings of the cosmetic outcomes after BCT. Independent rankings of the appearance of the nipple, overall breast shape, scarring, and skin were made by the patients as well as by a plastic surgeon, a breast oncologic surgeon, and a trained research assistant.

All objective measurements were similar between groups. The average volume of the breast undergoing lumpectomy was somewhat smaller (by about 100 cc) than that in the untreated breast, with no significant difference between African-American versus Caucasian patients.

…But Significant Differences in Subjective Ratings However, there was significant variation in subjective outcomes, with lower scores for African-American women. Patients and health care professionals both rated breast symmetry and appearance lower in African-American compared to Caucasian patients.

Nipple appearance and breast shape ratings were fairly consistent between patients and various health care professionals. However, there was wider variation when it came to scar appearance ratings.

Breast-conserving therapy is an important option for breast cancer treatment, with the potential for better final appearance of the breast. Some studies have reported racial/ethnic differences in cosmetic outcomes, including a lower rate of "good or excellent" outcomes in African-American women.

However, these studies have been limited by the lack of validated techniques for assessing breast appearance. If factors affecting the cosmetic outcomes of BCT can be established, it may be possible to tailor treatment approaches to achieve the best possible breast appearance while still providing effective control of breast cancer.

The new study shows similar objective outcomes for African American and Caucasian women undergoing BCT. However, it also finds lower subjective ratings of breast appearance for African-American patients. The researchers discuss the reasons for the racial differences, including a possible "psychological component."

The disagreement in scar ratings could reflect a higher rate of physical reactions to radiation therapy in African-American patients, which may be related to genetic factors. Dr. Galiano and coauthors conclude, "The novel techniques of cosmetic evaluation used in this study show promise towards identifying variables that can affect cosmetic outcome following BCT."

Plastic and Reconstructive Surgery—Global Open® is published by Lippincott Williams & Wilkins, part of Wolters Kluwer Health.

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About PRS Global Open Plastic and Reconstructive Surgery—Global Open (PRS GO) (www.prsgo.com) is a companion journal to the American Society of Plastic Surgeons’ flagship publication, Plastic and Reconstructive Surgery. PRS GO is an open access, rigorously peer-reviewed, international journal focusing on global plastic and reconstructive surgery. PRS GO educates and supports plastic surgeons globally to provide the highest quality patient care and maintain professional and ethical standards through education, research, and advocacy.

About ASPS The American Society of Plastic Surgeons (ASPS) is the world's largest organization of board-certified plastic surgeons. Representing more than 7,000 Member Surgeons, the Society is recognized as a leading authority and information source on aesthetic and reconstructive plastic surgery. ASPS comprises more than 94 percent of all board-certified plastic surgeons in the United States. Founded in 1931, the Society represents physicians certified by The American Board of Plastic Surgery or The Royal College of Physicians and Surgeons of Canada. ASPS advances quality care to plastic surgery patients by encouraging high standards of training, ethics, physician practice and research in plastic surgery. You can learn more and visit the American Society of Plastic Surgeons at www.plasticsurgery.org or www.facebook.com/PlasticSurgeryASPS and www.twitter.com/ASPS_news.

About Wolters Kluwer Health Wolters Kluwer Health is a leading global provider of information, business intelligence and point-of-care solutions for the healthcare industry. Serving more than 150 countries and territories worldwide, Wolters Kluwer Health’s customers include professionals, institutions and students in medicine, nursing, allied health and pharmacy. Major brands include Health Language®, Lexicomp®, Lippincott Williams & Wilkins, Medicom®, Medknow, Ovid®, Pharmacy OneSource®, ProVation® Medical and UpToDate®.

Wolters Kluwer Health is part of Wolters Kluwer, a market-leading global information services company. Wolters Kluwer had 2012 annual revenues of €3.6 billion ($4.6 billion), employs approximately 19,000 people worldwide, and maintains operations in over 40 countries across Europe, North America, Asia Pacific, and Latin America. Follow our official Twitter handle: @WKHealth.

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Plastic and Reconstructive Surgery—Global Open