Exploring Indicators of Early Breast Cancer Development in African American Women
Source Newsroom: Rutgers Cancer Institute of New Jersey
Newswise — New Brunswick, N.J., February 5, 2013 – The Cancer Institute of New Jersey and Cooper University Hospital -- a Major Clinical Research Affiliate of The Cancer Institute of New Jersey -- are working together on a non-therapy research study that examines factors related to the early development of breast cancer in African American women. Investigators will explore how these factors compare to those in Caucasian women. The Cancer Institute of New Jersey is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.
Compared to Caucasian women, African American women are more likely to be diagnosed with breast cancer at a younger age and at a later stage, and often have more aggressive features associated with a poor outcome. The reasons for these differences remain unknown. Through the Women’s Circle of Health study investigators at The Cancer Institute of New Jersey are exploring the influence of health and lifestyle factors on the early development of breast cancer in African American women. To address these issues, interviews will be conducted with study volunteers from nine counties across the state. African American women aged 20 to 75 who are newly diagnosed with breast cancer are eligible to participate, though other criteria must also be met.
Women meeting the eligibility criteria will be asked to give demographic and medical information, as well as reproductive, lifestyle and diet histories. A saliva sample will be also collected for genetic analyses. Participants do not need to take any medications.
The study is being offered at The Cancer Institute of New Jersey in New Brunswick and at Cooper University Hospital in Camden. It is being conducted in collaboration with the New Jersey State Cancer Registry and Roswell Park Cancer Institute and is supported by the National Cancer Institute (P01CA151135-01 – Ambrosone, Bandera).
Cancer Institute of New Jersey epidemiologist Elisa Bandera, MD, PhD, is the lead investigator. “This research study aims to understand how lifestyle and genetic factors impact the chances of developing cancer so that better prevention strategies can be developed. Previous breast cancer studies in African American and Caucasian women generally have been based on too few African American women to fully understand the differences between these two groups. By focusing on larger numbers of African American women, this study will provide new and important information about the causes of breast cancer in African American women,” noted Dr. Bandera, who is also an associate professor of epidemiology at UMDNJ-Robert Wood Johnson Medical School and UMDNJ-School of Public Health.
“This is a tremendous opportunity to say something meaningful about how lifestyle and genetic factors influence risks of breast cancer in African American women,” noted Robert Somer, MD, who is the principal investigator at Cooper University Hospital for the Women’s Circle of Health study.
For more information on how to take part in the Women’s Circle of Health Study can call 732-235-8806 or e-mail firstname.lastname@example.org.
“It is through volunteer participation that researchers are able to identify better ways to treat, prevent, diagnose and understand diseases such as cancer, which will result in improved patient outcomes,” said Susan Goodin, PharmD, deputy director at The Cancer Institute of New Jersey and associate director for clinical trials and therapeutics. “Our collaboration with Cooper University Hospital allows more access to these trials and allows for more everyday heroes throughout New Jersey to step forward to help us accomplish this mission,” noted Dr. Goodin, who is also a professor of medicine at UMDNJ-Robert Wood Johnson Medical School.
Clinical trials and research studies now underway at The Cancer Institute of New Jersey explore diagnosis, treatment and prevention of cancer, as well as management of cancer symptoms. The Cancer Institute of New Jersey currently enrolls more than 3,500 patients in clinical trials each year, including approximately 17 percent of all new adult cancer patients and approximately 70 percent of all pediatric cancer patients. That compares with fewer than five percent of all adult cancer patients enrolled nationwide.
As New Jersey’s only National Cancer Institute-designated Comprehensive Cancer Center, The Cancer Institute of New Jersey offers patients access to treatment options not available at other institutions within the state.
About The Cancer Institute of New Jersey
The Cancer Institute of New Jersey (www.cinj.org) is the state’s first and only National Cancer Institute-designated Comprehensive Cancer Center dedicated to improving the detection, treatment and care of patients with cancer, and serving as an education resource for cancer prevention. Physician-scientists at The Cancer Institute of New Jersey engage in translational research, transforming their laboratory discoveries into clinical practice, quite literally bringing research to life. To make a tax-deductible gift to support the Cancer Institute of New Jersey Foundation, call 732-235-8614 or visit www.cinjfoundation.org. Follow us on Facebook at www.facebook.com/TheCINJ.
The Cancer Institute of New Jersey Network is comprised of hospitals throughout the state and provides the highest quality cancer care and rapid dissemination of important discoveries into the community. Flagship Hospital: Robert Wood Johnson University Hospital. System Partner: Meridian Health (Jersey Shore University Medical Center, Ocean Medical Center, Riverview Medical Center, Southern Ocean Medical Center, and Bayshore Community Hospital). Major Clinical Research Affiliate Hospitals: Carol G. Simon Cancer Center at Morristown Medical Center, Carol G. Simon Cancer Center at Overlook Medical Center, and Cooper University Hospital. Affiliate Hospitals: CentraState Healthcare System, JFK Medical Center, Robert Wood Johnson University Hospital Hamilton (CINJ Hamilton), Somerset Medical Center, The University Hospital/UMDNJ-New Jersey Medical School*, and University Medical Center of Princeton at Plainsboro. *Academic Affiliate