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Opening the Entry Gate for DNA Replication

In a study published today in Genes & Development, Dr Christian Speck from the MRC Clinical Sciences Centre’s DNA Replication group, in collaboration with Brookhaven National Laboratory (BNL), New York, reveal the intricate mechanisms involved in the enzyme that governs DNA duplication during cell division.

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Depressive Symptoms and Pain May Affect Adherence and Health Outcomes in Dialysis Patients

Among patients on chronic hemodialysis, those with depressive symptoms and pain were more likely to abbreviate or miss dialysis sessions, visit the emergency department, and be hospitalized. Depressive symptoms were also linked with an increased risk of premature death.

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Patient-Centered Medical Homes Reduce Costs

As the number of patient centered medical homes has increased, a new report in the journal Health Services Research finds the model offers a promising option to reduce health care costs and utilization of some health care services.

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Medicine

Research on Digital Health, Alzheimer’s, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo

Nearly 20,000 medical professionals and healthcare leaders gathered for AACC’s 65th Annual Meeting & Clinical Lab Expo in Chicago from July 27–31. The meeting featured never-before-seen breakthroughs in diagnostic research and technology that will advance medicine and get patients the treatment they need.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 1-Aug-2014 5:00 PM EDT

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Blood and Saliva Tests Help Predict Return of HPV-Linked Oral Cancers

Physicians at Johns Hopkins have developed blood and saliva tests that help accurately predict recurrences of HPV-linked oral cancers in a substantial number of patients. The tests screen for DNA fragments of the human papillomavirus (HPV) shed from cancer cells lingering in the mouth or other parts of the body. A description of the development is published in the July 31 issue of JAMA Otolaryngology – Head & Neck Surgery.

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Algorithm Reduces Use of CT Scans When Diagnosing Children with Appendicitis

Implementation of an algorithm aimed to diagnose pediatric patients with suspected appendicitis reduces the utilization of computed tomography (CT) scans, without affecting diagnostic accuracy, Mayo Clinic Children's Center researchers have found. The study was recently published in the journal Surgery.

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Mayo Clinic Health Letter: Highlights from the July 2014 Issue

Here are highlights from the insert month issue of Mayo Clinic Health Letter, an eight-page monthly newsletter of reliable, accurate and practical information on today’s health and medical news.

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Unintended Consequences: More High School Math, Science Linked to More Dropouts

As U.S. high schools beef up math and science requirements for graduation, researchers at Washington University in St. Louis have found that more rigorous academics drive some students to drop out.

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Is It Really a Concussion? Symptoms Overlap with Neck Injuries, Making Diagnosis a Tough Call

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Athletes and others reporting cognitive difficulties after a head injury are usually diagnosed as having had a concussion. But is it really a concussion? A new study published by University at Buffalo medical faculty finds that many of the same symptoms are common to concussions and to injuries to the neck and/or balance system, known collectively as cervical/vestibular injuries.

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