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Big Data Allows Computer Engineers to Find Genetic Clues in Humans

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Computer scientists at Washington University in St. Louis tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.

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MRI Based on a Sugar Molecule Can Tell Cancerous from Noncancerous Cells

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Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn’t cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.

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Most NFL Players with Injuries to the Midfoot Return to Game Action

- Nearly 93 percent of National Football League (NFL) athletes who sustained traumatic injuries to the midfoot returned to competition less than 15 months after injury and with no statistically significant decrease in performance, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

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Weight-Loss Surgery Before Joint Replacement Can Improve Outcomes in Severely Overweight Patients

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Two new studies at Hospital for Special Surgery find that bariatric surgery prior to joint replacement is a cost-effective option to improve outcomes in severely overweight patients.

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MESA Complex Starts Largest Production Series in Its History

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Sandia National Laboratories has begun making silicon wafers for three nuclear weapon modernization programs, the largest production series in the history of its Microsystems and Engineering Sciences Applications complex.

Medicine

First Fully-Implantable Micropacemaker Designed for Fetal Use

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A team of investigators at Children’s Hospital Los Angeles and the University of Southern California have developed the first fully implantable micropacemaker designed for use in a fetus with complete heart block. The investigators anticipate the first human use of the device in the near future.

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What to Do with Kidneys From Older Deceased Donors?

• For older patients in need of a kidney transplant, rapid transplantation from an older deceased donor is superior to delayed transplantation from a younger donor. • Kidneys from older donors do not have sufficient longevity to provide younger patients with a lifetime of kidney function, but they do have sufficient longevity to provide older patients who have a shorter life expectancy with a lifetime of kidney function.

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Nobel Laureate, Leading Experts Speak in APS President’s Symposium Series

APS President David M. Pollock, PhD, has organized a dynamic President’s Symposium Series for EB 2015. Focused on the theme “Physiology: Answers to Big Questions,” experts will discuss how physiology can uncover solutions for diabetes, obesity and hypertension. The series is anchored by Nobel Laureate Robert J. Lefkowitz, PhD.

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A Possible Novel Therapy for a Rare but Potentially Fatal Blood Disorder

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A transgenic mouse model is a proof-of-concept that platelet blood cells that are loaded with the enzyme ADAMTS13 can be an effective treatment in murine models of thrombotic thrombocytopenic purpura.

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Endocrine Experts Support Screening for Thyroid Dysfunction in Pregnant Women

On March 24, The U.S. Preventive Services Task Force (USPSTF) issued a final recommendation statement on screening for thyroid dysfunction, concluding that the current evidence is insufficient to assess the balance of benefits and harms of screening for thyroid dysfunction in non-pregnant, asymptomatic adults.