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A reporter's PressPass is required to access this story until the embargo expires on 7-Jul-2015 11:00 AM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 7-Jul-2015 11:00 AM EDT

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Vanderbilt Research Could Lead to Vaccines and Treatment for Dengue Virus

Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.

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Genes May Not Be to Blame for Link Between Migraine and Heart Disease

A new study suggests that genes may not be to blame for the increased risk of heart disease some studies have shown in people with migraine, especially those with migraine with aura. The research is published during Headache/Migraine Awareness Month in the inaugural issue of the journal Neurology® Genetics, an open access, or free to the public, online-only, peer-reviewed journal from the American Academy of Neurology. Aura are sensations that come before the headache, often visual disturbances such as flashing lights.

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Genetic Variation Determines Protein’s Response to Anti-Diabetic Drug

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In the first study of its kind, researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. They aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

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Long-Term Memories Are Maintained by Prion-Like Proteins

Research from Eric Kandel’s lab has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time.

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McMaster Researchers Test Fecal Transplantation to Treat Ulcerative Colitis

The McMaster team recruited 75 patients with a flare up of their ulcerative colitis and randomized them to fecal transplant therapy given as an enema derived from stool donated by an anonymous healthy donor, and placebo.

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Discovery Points to a New Path Toward a Universal Flu Vaccine

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The conventional flu vaccine protects only against a few specific strains of flu. However, experiments by Rockefeller University researchers and their colleagues show that by including modified antibodies within the vaccine it may be possible to elicit broad protection against many strains simultaneously.

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New Measurements Reveal Differences Between Stem Cells for Treating Retinal Degeneration

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By growing two types of stem cells in a “3-D culture” and measuring their ability to produce retinal cells, a team lead by St. Jude Children’s Research Hospital researchers has found one cell type to be better at producing retinal cells. The research not only reveals which stem cell type might be better for treating retinal degeneration, but it also demonstrates a standardized method for quantifying the effectiveness of different stem cells for such therapies.

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Genetic Testing in Kids is Fraught with Complications

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Despite an increasing ease in acquiring genetic information, the American Society of Human Genetics (ASHG) points out that doing so has consequences, particularly when it comes to children. It is this population, they say, that is the most vulnerable. With this precaution in mind, the ASHG Workgroup on Pediatric Genetic and Genomic Testing has issued guidelines for genetic testing in children and adolescents that are based on a thorough review of studies on ethical, legal, and social implications (ELSI). The recommendations were published in The American Journal of Human Genetics.