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Rice Blast Research Reveals Details on How a Fungus Invades Plants

Like a stealthy enemy, blast disease invades rice crops around the world, killing plants and cutting production of one of the most important global food sources. Now, a study by an international team of researchers sheds light on how the rice blast fungus, Magnaporthe oryzae, invades plant tissue. The finding is a step toward learning how to control the disease, which by some estimates destroys enough rice to feed 60 million people annually.

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Wayne State University Breakthrough Research of Essential Molecule Reveals Important Targets in Diabetes and Obesity

A research team led by Assia Shisheva, Ph.D., professor of physiology in Wayne State University’s School of Medicine, has made breakthrough advancements on a molecule that may provide more answers in understanding the precise molecular mechanisms by which insulin regulates glucose uptake in fat and muscle cells.

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Scientists Catch EGFR Passing a Crucial Message to Cancer-Promoting Protein

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Signal tells MCM7 to launch DNA replication; pathway reduces breast cancer patient survival

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Study Finds Need for Improvement on State Health Care Price Websites

Greater relevance to patients could be realized by focusing information on services that are predictable, nonurgent, and subject to deductibles (e.g., routine outpatient care for chronic diseases) rather than services that are unpredictable, emergent, or would exceed most deductibles (e.g., hospitalizations for life-threatening conditions).

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Study Evaluates Procedures for Diagnosing Sarcoidosis

Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA.

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Markers of Beta-Cell Dysfunction Associated With High Rate of Progression to Type 1 Diabetes

The majority of children at risk of type 1 diabetes who developed 2 or more diabetes-related autoantibodies developed type 1 diabetes within 15 years, findings that highlight the need for research into finding interventions to stop the development of multiple islet autoantibodies, according to a study in the June 19 issue of JAMA.

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MMR Booster Vaccine Does Not Appear to Worsen Disease Activity in Children With Juvenile Arthritis

Among children with juvenile idiopathic arthritis (JIA) who had undergone primary immunization, the use of a measles-mumps-rubella (MMR) booster compared with no booster did not result in worse JIA disease activity, according to a study in the June 19 issue of JAMA.

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MRI Screening May Help Identify Spinal Infections From Contaminated Drug Injections

Magnetic resonance imaging (MRI) at the site of injection of a contaminated lot of a steroid drug to treat symptoms such as back pain resulted in earlier identification of patients with probable or confirmed fungal spinal or paraspinal infection, allowing early initiation of medical and surgical treatment, according to a study in the June 19 issue of JAMA.

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Earlier Treatment Following Stroke Linked With Reduced Risk of In-Hospital Death

In a study that included nearly 60,000 patients with acute ischemic stroke, thrombolytic treatment (to help dissolve a blood clot) that was started more rapidly after symptom onset was associated with reduced in-hospital mortality and intracranial hemorrhage and higher rates of independent walking ability at discharge and discharge to home, according to a study in the June 19 issue of JAMA.

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Hospital, Doctor Shopping Isn’t Easy for Patients Looking to Compare Prices of Health Care Services

State websites that publicly report health service prices rarely provide information that is relevant or usable for consumers, analysis in JAMA shows.

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