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Genetic Testing in Kids is Fraught with Complications

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Despite an increasing ease in acquiring genetic information, the American Society of Human Genetics (ASHG) points out that doing so has consequences, particularly when it comes to children. It is this population, they say, that is the most vulnerable. With this precaution in mind, the ASHG Workgroup on Pediatric Genetic and Genomic Testing has issued guidelines for genetic testing in children and adolescents that are based on a thorough review of studies on ethical, legal, and social implications (ELSI). The recommendations were published in The American Journal of Human Genetics.

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New Technique Maps Elusive Chemical Markers on Proteins

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Researchers have developed antibodies to help study critical chemical modifications responsible for a protein’s development

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Water to Understand the Brain

By using intrinsic optical signals (IOS) imaging, researchers from the University of Geneva (UNIGE), Switzerland, demonstrated that, contrary to what was thought, another physiological variation is involved: the activated neurons swell due to the massive entry of water. This discovery provides evidence that a much finer analysis of the functioning of the brain - and of its dysfunctions - is possible.

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First Comprehensive Analysis of the Woolly Mammoth Genome Completed

The first comprehensive analysis of the woolly mammoth genome reveals extensive genetic changes that allowed mammoths to adapt arctic life, including skin and hair development, insulin signaling, fat biology, and even traits such as small ears and short tails. A mammoth gene for temperature sensation was resurrected in the lab as a functional test.

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New Guidelines Recommend Stent Devices to Fight Strokes in Certain Patients

New devices called stent retrievers are enabling physicians to stop strokes in their tracks. For the first time, new guidelines from the American Heart Association/American Stroke Association recommend the treatment for certain stroke patients.

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Encryption Made Easier: Just Talk Like a Parent

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A Georgia Institute of Technology researcher has created an easier email encryption method – one that sounds familiar to parents who try to outsmart their 8-year-old child. The new technique gets rid of the complicated, mathematically generated messages that are typical of encryption software. Instead, the method transforms specific emails into ones that are vague by leaving out key words.

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Body Mass Index Impacts Ovarian Cancer Chemotherapy Dosages

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Ovarian cancer patients who are overweight or obese are often given less chemotherapy per pound of body weight in order to reduce the toxic side effects associated with higher doses, and this in turn may lower their chances of survival, according to a study by researchers at the Rutgers Cancer Institute of New Jersey and the Kaiser Permanente Northern California Division of Research.

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Cardiovascular Disease in Females—New Perspectives on Lifelong Risks

While heart disease is the number one cause of death in both sexes, it poses special considerations in women—with risks often beginning in childhood and changing at different stages of life. Insights on cardiovascular disease (CVD) risk in women and girls throughout the life span are shared in a special symposium feature in the June issue of The American Journal of Medical Sciences (AJMS). The official journal of the Southern Society for Clinical Investigation (SSCI), AJMS is published by Wolters Kluwer.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 8-Jul-2015 12:05 AM EDT

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Fresenius Medical Care’s Patient Engagement May Have Saved Lives During Superstorm Sandy

Fresenius Medical Care North America (FMCNA), a division of Fresenius Medical Care (NYSE: FMS) and North America’s largest provider of kidney care, hospitalist services and renal products, today hailed a new study by the Department of Health and Human Services (HHS) this week showing that dialysis patients who received treatments immediately before Super Storm Sandy experienced a much better survival rate and less frequent visits to the hospital. FMCNA provided pre-storm, weekend care to a wide section of the area surveyed by the study, indicating that the company’s efforts made an appreciable difference in patients’ lives.