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Medicine

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Breastfeeding, milk, Breast Milk, Lactation, Genomics, RNA Expression, Metabolic Disorder, Type 2 Diabetes, high-fat diet, Infant Health

High-Fat Diet May Change Breast Milk Makeup, Affect Baby's Health

New research suggests that following a high-fat diet during lactation—regardless of diet during pregnancy—alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring.

Medicine

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Immune System, Sleep, Nutritional Supplement, Wound, Wound Healing, Protein Supplement, Sleep Deprivation, skin, Skin Barrier Restoration

Getting Enough Sleep May Help Skin Wounds Heal Faster

Getting more sleep may help wound healing, and a nutrition supplement may also help, according to a new study. The paper, published ahead of print in the Journal of Applied Physiology, was chosen as an APSselect article for November.

Medicine

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Sickle Cell Disease, Red Cell Physiology, Red Blood Cells, Physiology, Vascular Physiology, Hemoglobin, Sickle Cell Treatment, Fetal Hemoglobin

Red Blood Cell Function, Creation and Renewal the Focus of Sickle Cell Conference Symposium

Researchers will meet to discuss the physiology, function and future of red blood cells (RBCs) in sickle cell disease (SCD) at the “Red Cell Physiology” symposium during the American Physiological Society’s Physiological and Pathophysiological Consequences of Sickle Cell Disease conference in Washington, D.C.

Medicine

Science

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Sickle Cell, Sickle Cell Disease, Gut Bacteria, Digestive System, Veillonella, Streptococcus Bacteria, Vascular Physiology, Physiology, Red Blood Cells

Out of Balance: Gut Bacterial Makeup May Exacerbate Pain in Sickle Cell Disease

An overabundance of the bacteria Veillonella in the digestive tract may increase pain in patients with sickle cell disease (SCD). Researchers from Howard University will present their findings today at the American Physiological Society’s Physiological and Pathophysiological Consequences of Sickle Cell Disease conference in Washington, D.C.

Medicine

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Sickle Cell Disease, Hemoglobin, Haptoglobin, Acute Chest Syndrome, Genotype, Genetic Testing, Physiological and Pathophysiological Consequences of Sickle Cell Disease Conference

Gene Marker Could Identify Sickle Cell Patients with Highest Risk of Complications

Researchers have found a genotype that could help identify sickle cell disease (SCD) patients at greatest risk of developing disease-related complications. The findings will be presented at the APS Physiological and Pathophysiological Consequences of Sickle Cell Disease conference.

Medicine

Science

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Physiology, Vascular Physiology, Red Cell Physiology, Stress, fear, Blood Vessel Constriction, Sickle Cell Disease, Hemoglobin, Red Blood Cell, Thrombosis, Occlusion

Stress, Fear of Pain May Be Cause of Painful Sickle Cell Episodes

Mental stress and the anticipation of pain may cause blood vessels to narrow and trigger episodes of severe pain (vaso-occlusive crisis, or VOC) in sickle cell disease (SCD). A team of researchers from California will present their findings today at the American Physiological Society’s Physiological and Pathophysiological Consequences of Sickle Cell Disease conference in Washington, D.C.

Medicine

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Clincial Trial, Sickle Cell Disease, Sickle Cell Therapy, Red Blood Cells, Red Cell Physiology, Small Molecules, Physiological and Pathophysiological Consequences of Sickle Cell Disease Conference

Alzheimer’s Drug Elicits Quality of Life, Red Blood Cell Function Improvements in Sickle Cell Patients

A popular drug commonly used to treat Alzheimer’s disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD). Researchers have found that the molecule memantine stabilizes the development, longevity and function of red blood cells and is well-tolerated by SCD patients. The findings will be presented at the APS Physiological and Pathophysiological Consequences of Sickle Cell Disease conference.

Medicine

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Sickle Cell, Sickle Cell Anemia Research, Sickle Cell Disease Treatment, Hemoglobin, Neural Circuits, Neurovascular Physiology, Cell Therapy, Gene Editing, Pharmacologic Treatment, Coagulation, Thrombosis, Renal physiology, Vascular Physiology, Lung Physiology, Red Cell Physiology, Small Molecule Therapy

Sickle Cell Conference to Focus on Causes and Pathways to a Cure

Leading experts in the field of sickle cell disease (SCD) research will convene in Washington, D.C., for the Physiological and Pathophysiological Consequences of Sickle Cell Disease conference (November 6–8). The conference, organized by the American Physiological Society (APS), will explore SCD—the world’s most prevalent single-gene mutation disease—and new research on preventing and reversing its deadly consequences.

Medicine

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High Blood Pressure, Hypertension, Kidney Disease, Kidney Injury, Gender Differences In Health, Sex Differences, Renal Disease, Hypertension Research

Hypertension in Women: Review Calls for More Data to Improve Treatment

Women account for half of all cases of high blood pressure (hypertension) in the U.S., yet the majority of hypertension research focuses on men. A review of more than 80 studies highlights sex differences in hypertension-related kidney (renal) disease and explores possible reasons why women respond differently than men. The article, published in the American Journal of Physiology—Renal Physiology, emphasizes the need for more hypertension research in females.

Medicine

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Type 1 Diabetes, Neuropathy, Exercise Tolerance, Nervous System, Nerve Response, Nerve Reflex, Heart Disease, Cardiovascular Disease, Blood Pressure, Circulation

Exercise Nerve Response in Type 1 Diabetes Worsens Over Time

A new study finds that late-stage type 1 diabetes mellitus (T1DM) weakens the autonomic reflex that regulates blood pressure during exercise, impairing circulation, nerve function and exercise tolerance.







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