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Article ID: 697416

The Love Lives of Fruit Flies

Harvard Medical School

New study reveals that a male fruit fly’s decision to court or ignore a female stems from the convergence of motivation, perception and chance that affects the balance of excitatory versus inhibitory signals in the brain to influence decision making. Findings may yield insights about addiction disorders, depression.

Released:
13-Jul-2018 1:05 PM EDT
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    12-Jul-2018 11:00 AM EDT

Article ID: 697196

Guardian of the Cell

Harvard Medical School

Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology The variations explain why the human protein is more precise and more selective than mammalian forms of the protein and why it targets certain types of DNA but ignores others The findings can inform the design of more precisely targeted immune therapies against cancer and a range of immune-mediated diseases

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9-Jul-2018 5:45 PM EDT
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Article ID: 697340

Bertarelli Foundation Invests in Promise of Translational Research to Tackle Sensory Disorders

Harvard Medical School

The Bertarelli Foundation has announced that it is redoubling its investment in this area of research, with a gift of $6.35 million to Harvard Medical School (HMS) to build on the previous successes of the Bertarelli Program in Translational Neuroscience and Neuroengineering.

Released:
12-Jul-2018 10:30 AM EDT
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  • Embargo expired:
    11-Jul-2018 1:00 PM EDT

Article ID: 697281

Rise of the Clones

Harvard Medical School

Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65

Released:
11-Jul-2018 10:30 AM EDT
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    9-Jul-2018 4:00 PM EDT

Article ID: 696957

In End-of-Life Cancer Care, Geography May Be Destiny

Harvard Medical School

Research reveals dramatic geographic differences in end-of-life care spending across the United States. Spending variations stemmed from doctors’ beliefs about end-of-life care and style of practice and from availability of health care services. Patient beliefs and preferences did not contribute to spending differences. Health care spending in the last month of life for patients with end-stage cancer in some regions is twice as high as that in other regions. The additional spending is wasteful and possibly harmful.

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2-Jul-2018 4:30 PM EDT
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Article ID: 696820

New Study Reveals the Function of a Mysterious Component of the Inner Ear

Harvard Medical School

A new study finds that a mysterious component of the inner ear acts as a pressure-relief valve, formed by a thin barrier of cellular projections that opens and closes to regulate the release of inner ear fluid.

Released:
28-Jun-2018 2:05 PM EDT
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Article ID: 696499

Warren Alpert Foundation Honors Pioneering Discoveries in Cystic Fibrosis

Harvard Medical School

The 2018 Warren Alpert Foundation Prizehas been awarded to five scientists for transformative discoveries in the fields of genetics, physiology, pulmonology and pharmacology that have led to the development of life-altering precision-targeted treatments for the devastating multiorgan disease cystic fibrosis (CF).

Released:
21-Jun-2018 4:30 PM EDT
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Article ID: 696423

Harvard Medical School Announces 2018 Media Fellowship: The Science of Pain

Harvard Medical School

Harvard Medical School’s Media Fellowship program, now entering its 21st year, is accepting applications for its fall 2018 session.

Released:
20-Jun-2018 4:30 PM EDT
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Article ID: 695769

In building the brain, cell pedigree matters

Harvard Medical School

Research in mice shows that a protein made by the stem cells that give rise to neurons, but not by neurons themselves, is key to brain cells’ ability to migrate during development and assume their proper positions. This primordial protein acts by clinging onto thousands of sites in the genome, affecting the activity of multiple genes that regulate brain development. The findings could yield valuable clues for a variety of neurodevelopmental disorders.

Released:
7-Jun-2018 11:35 AM EDT
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    4-Jun-2018 4:00 PM EDT

Article ID: 695379

Preventable Deaths from Lack of High-Quality Medical Care Cost the World More Than $6 Trillion in 2015 Alone

Harvard Medical School

Eight million largely preventable deaths from treatable diseases cost $6 trillion in lost economic welfare in low- and middle-income countries in 2015. If current conditions persist, low- and middle-income countries could lose collectively $11 trillion in gross domestic product by 2030, or 2.6 percent of total GDP in low-income countries. New analysis believed to be first to quantify global economic toll due to inadequate access to high-quality medical care. Findings stem from analysis of diseases in 130 low- and middle-income countries that are treatable with approaches commonly available in higher-income settings.

Released:
31-May-2018 11:30 AM EDT
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