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Embargo will expire:
27-Apr-2018 9:00 AM EDT
Released to reporters:
23-Apr-2018 9:05 AM EDT

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Article ID: 691899

Not-for-Profit Publishers Partner to Launch New Research Journal Life Science Alliance

The Rockefeller University Press

Rockefeller University Press, EMBO Press, and Cold Spring Harbor Laboratory Press today announced the launch of Life Science Alliance, a new global, open access, editorially independent, peer-reviewed journal committed to rapid, fair and transparent publication of valuable research from across the life sciences.

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3-Apr-2018 10:00 AM EDT
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  • Embargo expired:
    7-Mar-2018 9:00 AM EST

Article ID: 690247

Researchers Identify New Drugs That Could Help Prevent Hearing Loss

The Rockefeller University Press

Researchers from St. Jude Children’s Research Hospital have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 (CDK2) protects mice and rats from noise- or drug-induced hearing loss. The study, which will be published March 7 in the Journal of Experimental Medicine, suggests that CDK2 inhibitors prevent the death of inner ear cells, which has the potential to save the hearing of millions of people around the world.

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28-Feb-2018 10:05 AM EST
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  • Embargo expired:
    6-Mar-2018 9:00 AM EST

Article ID: 690244

How Tattoos Are Maintained by Macrophages Could Be Key to Improving Their Removal

The Rockefeller University Press

Researchers in France have discovered that, though a tattoo may be forever, the skin cells that carry the tattoo pigment are not. Instead, the researchers say, the cells can pass on the pigment to new cells when they die. The study, which will be published March 6 in the Journal of Experimental Medicine, suggests ways to improve the ability of laser surgery to remove unwanted tattoos.

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28-Feb-2018 9:05 AM EST
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    14-Feb-2018 9:00 AM EST

Article ID: 689123

Researchers Successfully Reverse Alzheimer’s Disease in Mouse Model

The Rockefeller University Press

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, thereby improving the animals’ cognitive function. The study, which will be published February 14 in the Journal of Experimental Medicine, raises hopes that drugs targeting this enzyme will be able to successfully treat Alzheimer’s disease in humans.

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7-Feb-2018 8:05 AM EST
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Article ID: 688756

New Explanation for Why Airways Close in Asthma Holds Promise for Future Class of Drugs

The Rockefeller University Press

Houston Methodist researchers have a new explanation for what causes the lungs’ airways to close during asthma attacks. The researchers who published the study in the Feb. 5 issue of the Journal of Experimental Medicine note that the discovery holds promise for developing a new class of drugs different from the steroids currently used to treat asthma.

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31-Jan-2018 2:05 PM EST
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Article ID: 687531

Mechanism That Converts White Fat to Brown Identified

The Rockefeller University Press

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat. The study is published in the Journal of Experimental Medicine.

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5-Jan-2018 9:05 AM EST
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    4-Jan-2018 9:00 AM EST

Article ID: 687335

Researchers Detect a Loophole in Chronic Lymphocytic Leukemia Treatment

The Rockefeller University Press

A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients. The study, which will be published January 4 in the Journal of Experimental Medicine, reveals that ibrutinib has a diminished capacity to delocalize and kill tumor cells expressing an adhesive protein called CD49d, but combining ibrutinib treatment with drugs that block CD49d activation could prevent the tumor cells from sheltering in lymphoid organs.

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2-Jan-2018 10:05 AM EST
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Article ID: 687359

Study Reveals How the Midshipman Fish Sustains Its Hour-Long Mating Call

The Rockefeller University Press

Researchers at the University of Pennsylvania have discovered how the Pacific midshipman fish can hum continuously for up to an hour in order to attract potential mates. The study, which is featured on the cover of the January 2018 issue of the Journal of General Physiology, explains how the muscle fibers surrounding the fish’s swimbladder can sustain the high rates of contraction—up to 100 times per second—that are needed to produce the animal’s distinctive call.

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2-Jan-2018 1:15 PM EST
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  • Embargo expired:
    21-Dec-2017 9:00 AM EST

Article ID: 686974

Researchers Map Molecular Interaction That Prevents Aggressive Breast Cancer

The Rockefeller University Press

Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast cancers more aggressive and resistant to chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome by preserving p53 levels.

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18-Dec-2017 9:05 AM EST
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