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Medicine

Science

Channels:

Antibiotic, Antimicrobial Peptides, Cholera, Vibrio cholerae, Biochemistry, Journal of Biological Chemistry

An Unusual Form of Antibiotic Resistance in Pandemic Cholera

Researchers at the University of Georgia have now shown that the enzyme that makes the El Tor family of V. cholerae resistant to those antibiotics has a different mechanism of action from any comparable proteins observed in bacteria so far. Understanding that mechanism better equips researchers to overcome the challenge it presents in a world with increasing antibiotic resistance. The results of this research are published in the Dec. 22, 2017 issue of the Journal of Biological Chemistry.

Medicine

Science

Channels:

Membrane Proteins, Biochemistry, Biophysics, Journal of Biological Chemistry, Drug Discovery

How a Biophysical Simulation Method Might Accelerate Drug Target Discovery

Researchers at the California Institute of Technology have developed an approach to overcome a major stumbling block in testing new drug targets. The research is reported in a Nov. 24 paper in the Journal of Biological Chemistry.

Science

Channels:

scientific publishing, scientific societies, Scientific Society Publisher Alliance

Qi-Qun Tang Joins Journal of Biological Chemistry

Qi-Qun Tang, a professor of in the department of biochemistry and molecular biology at the Fudan University School of Basic Medical Sciences in Shanghai, China, has joined the Journal of Biological Chemistry as an associate editor.

Medicine

Science

Channels:

Leukemia, GSK-3, phosphoproteomics, Biochemistry, Molecular Biology, Journal of Biological Chemistry

How an Interest in Bipolar Disorder Drugs Led to a Better Understanding of Leukemia

A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called GSK-3, will be published in the Nov. 3 issue of the Journal of Biological Chemistry.

Life

Education

Channels:

Science, eLife, Higher Education, Postdoctoral, Science Education, STEM Education Policy, Human Resources

What We Call Postdoctoral Researchers Matters, Scientists Say

In an opinion piece in the journal eLife, eight scientists and science policy experts make the case for standardizing how postdoctoral researchers are categorized by human resources offices and provide a framework that willing institutions can follow.

Science

Channels:

Biochemistry, Molecular Biology, Journal of Biological Chemistry, chaperone proteins, scientific publishing, scientific societies

Ursula Jakob Joins Journal of Biological Chemistry

Ursula Jakob, a professor of biological chemistry at the University of Michigan, has joined the Journal of Biological Chemistry as an associate editor.

Science

Channels:

Biochemistry, Molecular Biology, Epigenetics, Journal of Biological Chemistry

A Molecular Garbage Disposal Complex Has a Role in Packing the Genome

New research from the Korea Institute of Science and Technology, to be published in the Journal of Biological Chemistry on Oct. 13, has found that the proteasome, an essential protein complex that breaks down proteins in cells, has another unexpected function: directly regulating the packing of DNA in the nucleus.

Medicine

Channels:

Biochemistry, Blood, Thrombosis, Blood Clotting, antithrombin, Rare Diseases

What a Rare Blood Disease Can Teach Us About Blood Clotting

New insight into how the protein antithrombin works could lead to treatments not only for patients with antithrombin deficiency, but also to better-designed drugs for other blood disorders.

Medicine

Channels:

Biochemistry, Pharmacology, HIV, Combination Therapy

When HIV Drugs Don’t Cooperate

Researchers at Thomas Jefferson University studying combinations of drugs against HIV have discovered why certain drugs sometimes act synergistically but sometimes do not.

Science

Channels:

Biochemistry, Molecular Biology, Cell Biology, Journal of Biological Chemistry

Discovering What Makes Organelles Connect Could Help Understand Neurodegenerative Diseases

A study to be published in the September 29 issue of the Journal of Biological Chemistry reports the use of an emerging method to identify proteins that allows two organelles, the mitochondria and the endoplasmic reticulum, to attach to each other.







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