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Article ID: 689310

Alternative MRI Contrast Agent Performs Well in NIH Study

National Institute of Biomedical Imaging and Bioengineering

NIH-supported researchers at Massachusetts General Hospital are studying an alternative to current contrast agents used for magnetic resonance imaging. In a recent study, they showed that the experimental alternative, which is a manganese-based compound, performs as well as approved contrast agents. Their study appeared online Nov. 15, 2017, in Radiology.

Released:
14-Feb-2018 8:05 AM EST
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All Journal News, Grant Funded News, Neuro, Local - Maryland, Local - DC Metro

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Article ID: 689259

Artificial Kidney Development Advances, Thanks to Collaboration by NIBIB Quantum Grantees

National Institute of Biomedical Imaging and Bioengineering

Creating an artificial implantable kidney would be an epic advance in medicine and could address a chronic shortage of donor kidneys needed for transplant. Researchers who have been at this quest for the past 15 years face the challenge of how to keep the blood flowing smoothly through the artificial device without clotting. They are combining expertise in artificial kidney development and in computer simulation of blood flow to surmount the problem.

Released:
8-Feb-2018 1:05 PM EST
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Kidney Disease, Local - Maryland, Local - DC Metro, All Journal News, Grant Funded News

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Article ID: 688941

Engineers Use Natural Protein as Nanoshuttle for Anti-Cancer Vaccines

National Institute of Biomedical Imaging and Bioengineering

Clinical application of cancer fighting nanovaccines has been hampered by complications in large-scale manufacturing, quality control, and safety. Biomedical engineers developed nanovaccines that bind to the albumin protein naturally present in the body. The albumin protein then delivers these nanocomplexes to the lymph nodes, resulting in potent immune activation against multiple tumor types in mouse cancer models. The use of natural albumin as a universal vaccine shuttle is a significant step towards the application of cancer nanovaccine immunotherapy in humans.

Released:
5-Feb-2018 7:05 AM EST
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All Journal News, Cancer, Immunology, Respiratory Diseases and Disorders, Local - Maryland, Local - DC Metro

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Article ID: 688656

Fluorescent Nanoparticles Track Cancer Metastasis to Multiple Organs

National Institute of Biomedical Imaging and Bioengineering

Researchers funded by the National Institute Biomedical Imaging and Bioengineering (NIBIB), a part of the National Institutes of Health (NIH), have developed florescent nanoparticles that light up to track the progress of breast cancer metastasis. They are currently testing the particles in mice with the hope of someday being able to use them in humans.

Released:
30-Jan-2018 10:05 AM EST
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All Journal News, Cancer, Nanotechnology, Grant Funded News, Nature (journal), Local - Maryland, Local - DC Metro

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Article ID: 688213

Making Good Bacteria Better, and Easy to Track, Thanks to Genetic Engineering

National Institute of Biomedical Imaging and Bioengineering

Using an approach that combines ultrasound imaging and genetic engineering of bacterial microbes, a team from California Institute of Technology (Caltech), with funding from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), has created a powerful new system to track bacteria dispatched to deliver therapies deep inside the body.

Released:
19-Jan-2018 2:05 PM EST
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Biotech, Cell Biology, Engineering, Genetics, Nature (journal), Local - Maryland, Local - DC Metro, All Journal News, Grant Funded News

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Article ID: 687949

Squirtable Surgical Glue Could Transform Surgeries and Save Lives

National Institute of Biomedical Imaging and Bioengineering

Sutures and staples can be inadequate in complex surgeries and cannot make an air-tight or liquid-tight seal on a lung or artery wound or incision. Now researchers have created a surgical glue that sets to form an elastic air-tight or liquid-tight seal in just one minute. Successfully tested in animals, the sealant has enormous promise for life-saving use in humans.

Released:
16-Jan-2018 9:05 AM EST
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All Journal News, Surgery, Local - Maryland, Local - DC Metro, Grant Funded News

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Article ID: 687241

Pain-Free Skin Patch Responds to Sugar Levels for Management of Type 2 Diabetes

National Institute of Biomedical Imaging and Bioengineering

NIH researchers have devised a biochemically formulated patch of dissolvable microneedles for the treatment of type 2 diabetes. The biochemical formula of mineralized compounds in the patch responds to blood chemistry to manage glucose automatically. In a proof-of-concept study performed with mice, the researchers showed that the chemicals interact in the bloodstream to regulate blood sugar for days at a time.

Released:
22-Dec-2017 2:05 PM EST
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Diabetes, Healthcare, All Journal News, Nature (journal), Local - Maryland, Local - DC Metro

Article ID: 686298

Unique 3D Printer Creates Realistic Model of Patient Prostate, Aims to Vastly Improve Surgical Outcomes

National Institute of Biomedical Imaging and Bioengineering

NIBIB-funded scientists have developed a new technique for 3D-printing patient-specific organ models – here the prostate gland -- using polymers that accurately model the prostate’s dimensions and physical properties, while also providing quantitative tactile feedback, or response to pressure, incisions, and suturing.

Released:
6-Dec-2017 10:05 AM EST
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All Journal News, Cancer, Men's Health, Surgery, Technology, Local - Maryland, Local - DC Metro, Grant Funded News

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Article ID: 685930

“Swiss Army Knife” Nanovaccine Carries Multiple Weapons to Battle Tumors

National Institute of Biomedical Imaging and Bioengineering

Researchers at the National Institute of Biomedical Imaging and Bioengineering have developed a synergistic cancer nanovaccine packing DNA and RNA sequences that modulate the immune response, along with anti-tumor antigens, into one small nanoparticle. The nanovaccine produced an immune response that specifically killed tumor tissue, while simultaneously inhibiting tumor-induced immune suppression to block lung tumor growth in a mouse model of metastatic colon cancer.

Released:
29-Nov-2017 4:00 PM EST
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Cancer, Immunology, Vaccines, Local - Maryland, Local - DC Metro, All Journal News

  • Embargo expired:
    13-Nov-2017 5:00 AM EST

Article ID: 684985

Mirror Image: Researchers Create Higher-Quality Pictures of Biospecimens

National Institute of Biomedical Imaging and Bioengineering

Hari Shroff, Ph.D., chief of the National Institute of Biomedical Imaging and Bioengineering’s lab section on High Resolution Optical Imaging (HROI), and his team have spent the last few years developing optical microscopes that produce high resolution images at very high speed. After his lab develops these new microscopes, they release the plans and software for free, so any researcher can replicate the advances made at NIH. This latest microscope builds on previous improvements that Shroff’s lab had made with selective plane illumination microscopy (SPIM).

Released:
10-Nov-2017 8:00 AM EST
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Engineering, Technology, Local - Maryland, Local - DC Metro


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