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Medicine

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Alzheimer’s disease, Dementia, Centenarians, Aging, Longevity, Genetics

Einstein Researchers Receive $6 Million Grant to Untangle the Genetic Protections Against Alzheimer’s Disease

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The number of older adults with Alzheimer’s disease continues to rise, but the number of treatments for the condition has not kept pace. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have received a $6.3 million grant from the National Institutes of Health (NIH) to identify networks of genes in healthy centenarians that protect them against dementia. The results could help identify new targets for drugs to treat Alzheimer’s.

Medicine

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Alzheimer’s disease, Dementia, Cognitive Decline, Cognitive Function, Inflammation, Diet, multicultural population, Nutrition

NIH Funds Research to Fight Alzheimer’s Disease with Anti-Inflammatory Diet

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The National Institutes of Health has awarded Albert Einstein College of Medicine nutrition scientist Yasmin Mossavar-Rahmani, Ph.D., R.D., a five-year, $4 million grant to test whether a diet rich in foods with anti-inflammatory properties can reduce cognitive decline and Alzheimer's disease risk. Middle-aged and older participants from the Bronx will follow this diet, which is designed to appeal to a multicultural population, and researchers will measure cognitive function over time to assess its impact.

Medicine

Science

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Microbiome, microbiome and cancer treatment, Colorectal Cancer, gut microbes, gut microbiome, gut microbiomes, Chemotherapy, Diarrhea, Metabolic Activity

Gut Microbiome May Make Chemo Drug Toxic to Patients

Albert Einstein College of Medicine researchers report that the composition of people’s gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal cancer. The findings, described online today in npj Biofilms and Microbiomes, a Nature research journal, could help predict which patients will suffer side effects and prevent complications in susceptible patients.

Medicine

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Medical Education, healthcare careers, inclusive workforce;, Healthcare Disparities, Healthcare Leadership, Medical Students, Underrepresented Minority Groups, underrepresented minority students

Montefiore-Einstein Physician Awarded $1 Million to Train the Next Generation of Bronx-Grown Medical Professionals

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Juan Robles, M.D., attending physician at Montefiore Health System and assistant professor of family and social medicine at Albert Einstein College of Medicine, has earned a $1 million grant from the Health Resources and Services Administration (HRSA) to support Bronx students pursuing healthcare careers and create a more inclusive workforce dedicated to underserved communities.

Medicine

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Prostate Cancer, Beta Blockers, Nervous System

Study Shows How Nerves Drive Prostate Cancer

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In a study in today’s issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate. Their earlier research—which first implicated nerves in fueling prostate cancer—has prompted Montefiore-Einstein to conduct a pilot study testing whether beta blockers (commonly used for treating hypertension) can kill cancer cells in tumors of men diagnosed with prostate cancer.

Medicine

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anti-aging therapies, Aging, Longevity, Fountain Of Youth, Centenarians, longer life, longer lifespans

Einstein Researchers Share $9 Million Grant to Find Anti-Aging Therapies

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Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or later. To discover what’s special about the genes of centenarians—and apply that knowledge to extend the healthy lives of the rest of us—the NIH has awarded researchers at Albert Einstein College of Medicine and The Scripps Research Institute (TSRI) a five-year, $9 million grant.

Medicine

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Cancer, Leukemia, Cells, Cell Death, Research, Biochemistry, Proteins, anti-cancer drugs, Chemotherapy

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells. The new treatment approach, described in today’s issue of Cancer Cell, was directed against acute myeloid leukemia (AML) cells but may also have potential for attacking other types of cancers.

Medicine

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Virus, Viruses, Ebola, Marburg, hantaviruses, Pathogens, Microbiology, Antibodies, Filoviruses, Disease, Vaccines

Einstein Researchers Awarded Three NIH Grants Totaling $12Million to Fight Virulent Viruses

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The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses—Ebola, Marburg and hantavirus. Research collaborations between Kartik Chandran, Ph.D., professor of microbiology & immunology and the Harold and Muriel Block Faculty Scholar in Virology, and Jonathan Lai, Ph.D., associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments.

Medicine

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Medical Marijuana, Cannabis, Opioid use, Chronic Pain, pain, HIV

First Long-Term Study on Medical Marijuana’s Impact on Opioid Use for Pain

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The National Institutes of Health (NIH) has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $3.8 million grant for the first long-term study to test whether medical marijuana reduces opioid use among adults with chronic pain, including those with HIV.

Medicine

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Aging, aging and the brain, hypothalmus, hypothalmic stem cells, Age-related Diseases, extending lifespan, reverse aging, Micrornas, Mirnas

Brain Cells Found to Control Aging

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Scientists at Albert Einstein College of Medicine have found that stem cells in the brain’s hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan. The paper was published online today in Nature.







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