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Article ID: 694882

Clues Found to Early Lung Transplant Failure

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis and Northwestern University have uncovered cells that flow into and harm the lung soon after transplant. The resulting dysfunction is the leading cause of early death after lung transplantation. The discovery, in mice, may lead to drug therapies that target the destructive cells.

Released:
21-May-2018 4:00 PM EDT
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    21-May-2018 2:15 PM EDT

Article ID: 694780

Eczema Drug Effective Against Severe Asthma

Washington University in St. Louis

Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients’ ability to breathe better than standard therapies. Dupilumab, an injectable anti-inflammatory drug, was approved in 2017 by the Food and Drug Administration as a treatment for eczema, a chronic skin disease.

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17-May-2018 4:35 PM EDT
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    17-May-2018 12:00 PM EDT

Article ID: 694608

Blood Type Affects Severity of Diarrhea Caused by E. coli

Washington University in St. Louis

A new study shows that a kind of E. coli most associated with “travelers’ diarrhea” and children in underdeveloped areas of the world causes more severe disease in people with blood type A. The bacteria release a protein that latches onto intestinal cells in people with blood type A, but not blood type O or B. A vaccine targeting that protein could potentially protect people with type A blood against the deadliest effects of E. coli infection.

Released:
15-May-2018 1:05 PM EDT
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    16-May-2018 1:00 PM EDT

Article ID: 694527

Why Chikungunya, Other Arthritis-Causing Viruses Target Joints

Washington University in St. Louis

Scientists have understood little about how chikungunya and related viruses cause arthritis. Now, researchers at Washington University School of Medicine in St. Louis have identified the molecular handle that chikungunya grabs to get inside cells. The findings, published May 16 in the journal Nature, could lead to ways to prevent or treat disease caused by chikungunya and related viruses.

Released:
14-May-2018 1:05 PM EDT
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Article ID: 694554

WashU Expert: Trump’s Drug Pricing Plan Breaks Little New Ground

Washington University in St. Louis

President Donald Trump, in a long-anticipated speech May 11, proclaimed to target reducing drug prices in America.But there is little in the speech or the administration’s plan that takes direct aim at industry, despite the president’s tough talk against pharmaceutical company pricing practices, says an expert on drug policy at Washington University in St.

Released:
14-May-2018 3:45 PM EDT
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Law and Public Policy

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Article ID: 694493

An ‘Unprecedented Look’ Into the Protein Behind Hypertension, Epilepsy and Other Conditions

Washington University in St. Louis

The seemingly unrelated conditions of hypertension, epilepsy and overactive bladder may be linked by electrical activity in a protein long studied by a biomedical engineer at Washington University in St. Louis. After new technology recently revealed the structure of the protein, his lab will collaborate with two others to take an unprecedented look into its molecular mechanisms, potentially leading to the development of new drugs for these and other conditions.

Released:
14-May-2018 9:40 AM EDT
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Article ID: 694097

Vector Ecologist Available to Discuss Factors That Influence Mosquito Ecology and Evolution

Washington University in St. Louis

Released:
4-May-2018 3:35 PM EDT
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    3-May-2018 2:00 PM EDT

Article ID: 693744

How a Light Touch Can Spur Severe Itching

Washington University in St. Louis

Scientists at the Washington University Center for the Study of Itch have found that itching caused by touch is directly related to the number of touch receptors embedded in the skin. His team found, in mice, that fewer receptors make it more likely touching will induce itching.

Released:
30-Apr-2018 4:00 PM EDT
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Article ID: 693865

Wildlife Ecologist Available to Discuss Ecology of Ticks and Tick-Borne Pathogens

Washington University in St. Louis

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2-May-2018 9:05 AM EDT
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    30-Apr-2018 11:00 AM EDT

Article ID: 693647

Bacteria’s Appetite May Be Key to Cleaning Up Antibiotic Contamination

Washington University in St. Louis

Some bacteria not only escape being killed by bacteria, they turn it into food. Until now, scientists have understood little about how bacteria manage to consume antibiotics safely, but new research from Washington University School of Medicine in St. Louis illuminates key steps in the process. The findings, published April 30 in Nature Chemical Biology, could lead to new ways to eliminate antibiotics from land and water, the researchers said. Environmental antibiotic contamination promotes drug resistance and undermines our ability to treat bacterial infections.

Released:
27-Apr-2018 12:05 PM EDT
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