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Embargo will expire:
27-Feb-2018 12:00 PM EST
Released to reporters:
22-Feb-2018 8:00 AM EST

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Feb-2018 12:00 PM EST

Channels:

Blood Disorders, Cell Biology, Technology, Local - California, Grant Funded News, All Journal News

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Article ID: 688357

Discovery May Advance Neural Stem Cell Treatments for Brain Disorders

Sanford Burnham Prebys Medical Discovery Institute

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease, Parkinson’s disease, and mental health disorders that affect cognitive abilities.

Released:
24-Jan-2018 9:00 AM EST
EXPERT AVAILABLE
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Channels:

Cell Biology, Neuro, Alzheimer's and Dementia, Nature (journal), Local - California, All Journal News, Grant Funded News

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  • Embargo expired:
    18-Dec-2017 10:00 AM EST

Article ID: 686997

Gut Reaction: Repeated Food Poisoning Triggers Chronic Disease

Sanford Burnham Prebys Medical Discovery Institute

Small bacterial infections that may go unnoticed and which the body easily clears without treatment, such as occurs during mild food poisoning, nevertheless can start a chain of events that leads to chronic inflammation and potentially life-threatening colitis.

Released:
21-Dec-2017 2:00 PM EST
EXPERT AVAILABLE
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  • Embargo expired:
    14-Dec-2017 12:00 PM EST

Article ID: 686796

Researchers Track Muscle Stem Cell Dynamics in Response to Injury and Aging

Sanford Burnham Prebys Medical Discovery Institute

A new study led by SBP describes the biology behind why muscle stem cells respond differently to aging or injury. The findings, published in Cell Stem Cell, have important implications for the normal wear and tear of aging.

Released:
13-Dec-2017 4:35 PM EST
EXPERT AVAILABLE
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Channels:

All Journal News, Cell Biology, Stem Cells, Cell (journal), Local - California, Grant Funded News, Aging

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Article ID: 686573

Insights on How SHARPIN Promotes Cancer Progression

Sanford Burnham Prebys Medical Discovery Institute

SBP and Technion Institute researchers have SHARPIN-ed their knowledge of how a malicious form of a protein drives the formation of melanoma through modulation of the PRMT5 pathway. The new research was published in The Journal of Clinical Investigation.

Released:
11-Dec-2017 4:00 PM EST
EXPERT AVAILABLE
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Channels:

All Journal News, Cancer, Dermatology, Grant Funded News, Local - California

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Article ID: 686097

Research Suggests New Pathways for Hyperaldosteronism

Sanford Burnham Prebys Medical Discovery Institute

Scientists have identified a mechanism that explains the development of hyperaldosteronism, a condition in which the adrenal glands produce too much aldosterone, The findings, published in JCI Insight, offer a path for drug discovery to treat the condition.

Released:
7-Dec-2017 9:05 AM EST
EXPERT AVAILABLE
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Channels:

All Journal News, Blood Disorders, Cancer, Pharmaceuticals, Local - California, Grant Funded News

  • Embargo expired:
    1-Dec-2017 9:00 AM EST

Article ID: 685985

D’Angelo Receives American Cancer Society Research Scholar Grant

Sanford Burnham Prebys Medical Discovery Institute

Maximiliano D’Angelo, Ph.D., an assistant professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), has received a four-year, $792,000 Research Scholar Grant from the American Cancer Society.

Released:
1-Dec-2017 5:00 AM EST
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  • Embargo expired:
    23-Nov-2017 5:00 AM EST

Article ID: 685512

Scientists Find Key to Regenerating Blood Vessels

Sanford Burnham Prebys Medical Discovery Institute

Florida researchers have identified a signaling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels. The findings, published in Nature Communications, may improve current strategies to improve blood flow in ischemic tissue, such as that found in atherosclerosis and peripheral vascular disease associated with diabetes.

Released:
20-Nov-2017 2:00 PM EST
EXPERT AVAILABLE
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Channels:

Cell Biology, Chemistry, Diabetes, Regenerative Medicine, Nature (journal), Local - California, All Journal News, Grant Funded News

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Article ID: 685497

Preclinical Study Demonstrates Promising Treatment for Rare Bone Disease

Sanford Burnham Prebys Medical Discovery Institute

Researchers have demonstrated that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE). The research, published in the Journal of Bone and Mineral Research, is an important step toward an effective pharmacological treatment for MHE, a rare genetic condition that affects about 1 in 50,000 people worldwide.

Released:
21-Nov-2017 9:00 AM EST
EXPERT AVAILABLE
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Channels:

All Journal News, Grant Funded News, Arthritis, Bone Health, Cancer, Local - California

Article ID: 685239

Anti-Malaria Drug Shows Promise as Zika Virus Treatment

Sanford Burnham Prebys Medical Discovery Institute and UC San Diego School of Medicine

California researchers have discovered that a medication used to prevent and treat malaria may also be effective for Zika virus. The drug, called chloroquine, has a long history of safe use during pregnancy, and is relatively inexpensive. The research was published today in Scientific Reports.

Released:
17-Nov-2017 5:00 AM EST
EXPERT AVAILABLE
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Channels:

All Journal News, Grant Funded News, Infectious Diseases, Zika Virus, Pharmaceuticals, Scientific Reports, Local - California


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