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  • Embargo expired:
    26-Jul-2018 11:00 AM EDT

Article ID: 697829

Dr. Jekyll, Mr. Hyde: Study Reveals Healing Mesenchymal Cells Morph and Destroy Muscles in Models of Spinal Cord Injury, ALS and Spinal Muscular Atrophy

Sanford Burnham Prebys Medical Discovery Institute

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP), in collaboration with the Fondazione Santa Lucia IRCCS in Rome, have discovered a new disease-specific role of FAP cells in muscle wasting and scarring, indicating a potential new avenue for treating motor neuron diseases.

Released:
24-Jul-2018 12:00 PM EDT
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Article ID: 697482

Sanford Burnham Prebys Announces Leadership Team Appointments: Louie Coffman Joins as Chief Financial Officer and Angelica Gamble-Wong as Vice President of Human Resources

Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys Medical Discovery Institute (SBP) announced today that Louie Coffman has been appointed chief administrative officer and chief financial officer, and Angelica Gamble-Wong has been appointed vice president of Human Resources (HR).

Released:
17-Jul-2018 8:00 AM EDT
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Article ID: 696590

SBP Researchers Awarded 2018 Padres Pedal the Cause Grants

Sanford Burnham Prebys Medical Discovery Institute

SBP is pleased to announce that it has been awarded four Padres Pedal the Cause (PPTC) collaborative grants with UCSD Moores Cancer Center. The projects funded include research to help understand cancer and find novel therapies that exploit its vulnerabilities. The awards are part of the $2.4 million raised in the November 2017 cycling event—the largest annual contribution in the five-year history of the organization.

Released:
25-Jun-2018 1:00 PM EDT
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Article ID: 695784

SBP Partners with Nation’s Top Cancer Centers to Endorse Goal of Eliminating HPV-related Cancers in the United States

Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys is one of 70 National Cancer Institute (NCI)-designated cancer centers to issue a statement urging for increased HPV vaccination and screening to eliminate HPV-related cancers, starting with cervical cancer. These institutions collectively recognize insufficient vaccination as a public health threat and call upon the nations’ physicians, parents and young adults to take advantage of this rare opportunity to eliminate several different types of cancer in men and women.

Released:
7-Jun-2018 2:05 PM EDT
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Law and Public Policy

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  • Embargo expired:
    7-May-2018 11:00 AM EDT

Article ID: 693891

Nuclear Pore Functions Are Essential for T Cell Survival

Sanford Burnham Prebys Medical Discovery Institute

A new study by Sanford Burnham Prebys (SBP) researchers describes how a specific nuclear pore component is critical for the survival of circulating T cells. The findings, published in Nature Immunology, identify a new node of T cell receptor signaling and could pave the way for the development of future immunotherapies.

Released:
4-May-2018 8:00 AM EDT
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  • Embargo expired:
    3-May-2018 11:00 AM EDT

Article ID: 693776

Study Offers New Approach to Starve p53 Deficient Tumors

Sanford Burnham Prebys Medical Discovery Institute

SBP researchers recently discovered an alternative metabolic pathway that might be used by cancer cells to survive nutrient deprivation. Targeting these proteins to disrupt autophagy in cancer cells is an exciting therapeutic strategy that could minimize toxicity.

Released:
1-May-2018 11:00 AM EDT
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  • Embargo expired:
    24-Apr-2018 12:00 PM EDT

Article ID: 693148

How Colorectal Cancer Cells Spread to the Liver

Sanford Burnham Prebys Medical Discovery Institute

A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers helps explain the connection between a tumor suppressor called protein kinase C zeta (PKC zeta) and metastatic colorectal cancer.

Released:
20-Apr-2018 12:00 PM EDT
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Article ID: 693222

San Diego Leaders, Researchers Announce Milestone Grant as Alzheimer's Crisis Widens

Sanford Burnham Prebys Medical Discovery Institute

A coalition of brain scientists and civic leaders, including Mayor Kevin Faulconer and county Supervisors Dianne Jacob and Kristin Gaspar, announced that the federal government has awarded a $1.3 million grant to Sanford Burnham Prebys Medical Discovery Institute to advance the local search for a cure for Alzheimer's.

Released:
20-Apr-2018 10:05 AM EDT
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  • Embargo expired:
    9-Apr-2018 12:00 PM EDT

Article ID: 692333

Study Finds How Fat Tissue Shunts Energy to Tumors

Sanford Burnham Prebys Medical Discovery Institute

Sanford Prebys Medical Discovery Institute (SBP) researchers recently discovered that that inactivation of a protein called p62 in fat cells fuels aggressive, metastatic prostate cancer in mice. The findings suggest that mTOR inhibitors currently used to treat a wide range of cancers may have the unintended consequence of shutting down fat tissue metabolism and fueling tumor growth.

Released:
6-Apr-2018 12:00 AM EDT
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Article ID: 692222

Evan Snyder Elected to Association of American Physicians

Sanford Burnham Prebys Medical Discovery Institute

Evan Y. Snyder, M.D., Ph.D., professor and founding director, Center for Stem Cells & Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute (SBP) and professor at the University of California San Diego, has been elected to membership in the Association of American Physicians (AAP).

Released:
4-Apr-2018 12:00 PM EDT
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