Press "esc" to clear
Go to Advanced Search

Showing results

110 of 298
Maximiliano_DAngelo-6861.jpg
  • Embargo expired:
    7-May-2018 11:00 AM EDT

Article ID: 693891

Nuclear Pore Functions Are Essential for T Cell Survival

Sanford Burnham Prebys Medical Discovery Institute

A new study by Sanford Burnham Prebys (SBP) researchers describes how a specific nuclear pore component is critical for the survival of circulating T cells. The findings, published in Nature Immunology, identify a new node of T cell receptor signaling and could pave the way for the development of future immunotherapies.

Released:
4-May-2018 8:00 AM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
brooke_emerling_10-17-9989.jpg
  • Embargo expired:
    3-May-2018 11:00 AM EDT

Article ID: 693776

Study Offers New Approach to Starve p53 Deficient Tumors

Sanford Burnham Prebys Medical Discovery Institute

SBP researchers recently discovered an alternative metabolic pathway that might be used by cancer cells to survive nutrient deprivation. Targeting these proteins to disrupt autophagy in cancer cells is an exciting therapeutic strategy that could minimize toxicity.

Released:
1-May-2018 11:00 AM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
jorge_moscat-2_0.jpg
  • Embargo expired:
    24-Apr-2018 12:00 PM EDT

Article ID: 693148

How Colorectal Cancer Cells Spread to the Liver

Sanford Burnham Prebys Medical Discovery Institute

A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers helps explain the connection between a tumor suppressor called protein kinase C zeta (PKC zeta) and metastatic colorectal cancer.

Released:
20-Apr-2018 12:00 PM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
MayorFaulconer.png

Article ID: 693222

San Diego Leaders, Researchers Announce Milestone Grant as Alzheimer's Crisis Widens

Sanford Burnham Prebys Medical Discovery Institute

A coalition of brain scientists and civic leaders, including Mayor Kevin Faulconer and county Supervisors Dianne Jacob and Kristin Gaspar, announced that the federal government has awarded a $1.3 million grant to Sanford Burnham Prebys Medical Discovery Institute to advance the local search for a cure for Alzheimer's.

Released:
20-Apr-2018 10:05 AM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
Photo15MoscatDiazMeco.jpeg
  • Embargo expired:
    9-Apr-2018 12:00 PM EDT

Article ID: 692333

Study Finds How Fat Tissue Shunts Energy to Tumors

Sanford Burnham Prebys Medical Discovery Institute

Sanford Prebys Medical Discovery Institute (SBP) researchers recently discovered that that inactivation of a protein called p62 in fat cells fuels aggressive, metastatic prostate cancer in mice. The findings suggest that mTOR inhibitors currently used to treat a wide range of cancers may have the unintended consequence of shutting down fat tissue metabolism and fueling tumor growth.

Released:
6-Apr-2018 12:00 AM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
EvanSnyder.jpg

Article ID: 692222

Evan Snyder Elected to Association of American Physicians

Sanford Burnham Prebys Medical Discovery Institute

Evan Y. Snyder, M.D., Ph.D., professor and founding director, Center for Stem Cells & Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute (SBP) and professor at the University of California San Diego, has been elected to membership in the Association of American Physicians (AAP).

Released:
4-Apr-2018 12:00 PM EDT
EXPERT AVAILABLE
Open in New Tab
Comment
huaxixu-1019.jpg
  • Embargo expired:
    7-Mar-2018 12:00 PM EST

Article ID: 690563

The Brain’s Immune System May Be Key to New Alzheimer’s Treatments

Sanford Burnham Prebys Medical Discovery Institute

SBP researchers have revealed how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function. The research suggests boosting TREM2 levels in the brain may prevent or reduce the severity of neurodegenerative disorders including Alzheimer’s disease.

Released:
5-Mar-2018 4:00 PM EST
EXPERT AVAILABLE
Open in New Tab
Comment
not_final-3217.jpg
  • Embargo expired:
    6-Mar-2018 12:00 PM EST

Article ID: 690465

Controlling Ceramides Could Help Treat Heart Disease

Sanford Burnham Prebys Medical Discovery Institute

SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today in Cell Reports, also identified several potential therapeutic targets that could prevent or reverse the effects of LCM.

Released:
5-Mar-2018 11:00 AM EST
EXPERT AVAILABLE
Open in New Tab
Comment
not_final_-6053.jpg
  • Embargo expired:
    27-Feb-2018 12:00 PM EST

Article ID: 689932

Novel Genome Platform Reveals New HIV Targets

Sanford Burnham Prebys Medical Discovery Institute

SBP researchers have developed the first ever high-throughput, genome-scale imaging-based approach to investigate protein stability. The method has been used to identify several previously unknown human proteins that HIV degrades to enhance its infection process.

Released:
22-Feb-2018 8:00 AM EST
EXPERT AVAILABLE
Open in New Tab
Comment
CrystalZhao.jpg

Article ID: 688357

Discovery May Advance Neural Stem Cell Treatments for Brain Disorders

Sanford Burnham Prebys Medical Discovery Institute

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease, Parkinson’s disease, and mental health disorders that affect cognitive abilities.

Released:
24-Jan-2018 9:00 AM EST
EXPERT AVAILABLE
Open in New Tab
Comment

Showing results

110 of 298





Chat now!