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Medicine

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heart failure, heart assist device, cardiomyopathy, gene expression, risk prediction

Genomic Blood Test Predicts Survival Rates After Surgery for Advanced Heart Failure

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An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

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UCLA Study Finds Link Between Breast Cancer Treatments and Cellular Markers of Aging

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A new study has found that women who had received chemotherapy and/or radiation to treat breast cancer were more likely to have high levels of DNA damage and reduced activity of an enzyme involved in chromosome healing, compared to women who underwent surgery alone. The results suggest that some breast cancer survivors may be more vulnerable to biological changes associated with accelerated aging because of their prior treatment.

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Researchers Uncover Cell Changes Behind Therapy-Resistant Cancers, Call for New Clinical Approaches

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A UCLA study in collaboration with the California Institute of Technology (Caltech) shows that skin cancer cells could be chemically changed from within to reflexively alter gene expression patterns and intracellular pathways, which allows the cells to become resistant to targeted drugs.

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Diabetes, Diabetes and Adults, Diabetes Research, Congenital Heart Defect, Congenital Heart Defects, congenital heart abnormalities, Pregnancy, Pregnancy and Diabetes, stem cells and diabetes, Stem Cell Biology, Stem Cells

Research Reveals How Diabetes in Pregnancy Affects Baby’s Heart

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Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered how high glucose levels - whether caused by diabetes or other factors - keep heart cells from maturing normally. Their findings help explain why babies born to women with diabetes are more likely to develop congenital heart disease.

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Health Tips, Allergies, Chronic Disease, Lifestyle, Lifestyle Changes, UCLA health, health calendar, Year End Lists

Here Are the Things Patients Should Be Doing for Their Health, but Aren’t

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Year-end is a great time to reflect on our health and endeavor to improve it. As we do so, it's important to identify the steps that could have a big impact on our wellness.

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Drug Offers New Hope to Fight Relapse in People with Kidney Cancer

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Sunitinib (marketed as Sutent) a drug that has already proven highly effective as first-line treatment for people with metastatic renal cell carcinoma, was recently approved by the U.S. Food and Drug Administration to also treat patients with the disease who are at high risk for tumor recurrence.

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Alzheimer's Disease, Mild Cognitive Impairment, Public Health, Aging

Population of Americans with Alzheimer’s Will More Than Double by 2060, UCLA Study Shows

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About 15 million Americans will have either Alzheimer’s dementia or mild cognitive impairment by 2060, up from approximately 6.08 million this year. The findings highlight the need to develop preventive measures that could slow the progression of the disease in at risk for Alzheimer’s dementia.

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Hospitalization, Holiday, Holiday Blues, Family

Hospitalized During the Holidays? It’s Normal to Feel Blue

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Being in the hospital can happen any time of the year, but when it occurs during the holidays it can seem pretty unfair.

Medicine

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OpenNotes, OurNotes, Patient records, medical charts, medical notes, Electronic Medical Records

Medical Note System Could Boost Patients’ Engagement in Their Health Care

In research published in the Annals of Internal Medicine, doctors at UCLA Health and Beth Israel Deaconess Medical Center found that patients could benefit if they are invited to co-produce medical notes, called “OurNotes,” with their doctors, rather than merely reading them.

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With $6.6 Million Award From PCORI, UCLA Scientists to Study Effectiveness of Strategies Designed to Increase the Use of the HPV Vaccine to Prevent Cancer

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UCLA researcher Dr. Roshan Bastani will lead a $6.6 million research study awarded by the Patient-Centered Outcomes Research Institute (PCORI) to investigate the comparative effectiveness of strategies designed to increase receipt of the human papillomavirus (HPV) vaccine among adolescents. By advancing the understanding of which health system interventions are most effective and efficient, the research has the potential to dramatically increase HPV vaccination and prevent HPV-related cancers nationwide.







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