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Medicine

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Breast Cancer, Tumor Biology, Therapeutics, Methionine

Ludwig Researchers Uncover Mechanism Behind a Metabolic Vulnerability of Certain Breast Cancers

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Many cancer cells are relatively sensitive to the deprivation of an essential amino acid known as methionine. Now, a Ludwig Cancer Research study published in the journal Science Signaling and led by Alex Toker, an investigator in the Ludwig Center at Harvard, has elucidated one mechanism behind that dependency.

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Breakthrough Prize, ALS, Huntington's Disease, Life Science, Alzheimer's Disease, Cancer

Ludwig Cancer Research Scientist Don Cleveland Wins Breakthrough Award

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Ludwig Cancer Research extends its warmest congratulations to Don Cleveland, who has been a Member of the Ludwig Institute for Cancer Research since 1995 and today was awarded the prestigious Breakthrough Prize.

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Cancer, Radiotherapy, Immune Response

Ludwig Researchers Unravel Novel Mechanism by Which Tumors Grow Resistant to Radiotherapy

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A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development.

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Cancer, gliblastoma, Neuro-oncology, Brain Tumor

Ludwig Scientists Share Findings on Development and Treatment of Glioblastoma at the 2017 Society for Neuro-Oncology Annual Meeting

Ludwig Cancer Research has released the scope of its participation at this year’s Annual Meeting and Education Day of the Society for Neuro-Oncology in San Francisco, California, November 16-19.

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Melanoma, Immunotherapy, Apoptosis, FAS

Ludwig Researchers Uncover Novel Mechanism by Which Tumors Evade a Variety of Cancer Immunotherapies

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

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Immunotheapy, PD-1, Tumor Microenvironment

Ludwig Scientists Share Insights on Immunotherapy Research at the 2017 Society for Immunotherapy of Cancer Annual Meeting

Ludwig Cancer Research has released the scope of its participation at the 2017 Society for Immunotherapy of Cancer (SITC) Annual Meeting in National Harbor, Maryland, November 8-12.

Medicine

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Acute Promyelocytic Leukemia, Immune Cells, immune suppression, Prostate Cancer

Ludwig Scientists Discover Complex Axis of Immune Suppression Exploited by Cancers

A Ludwig Cancer Research study has uncovered a new mechanism by which cancer cells evade destruction by the immune system. The paper, led by Camilla Jandus of the Lausanne Branch of the Ludwig Institute for Cancer Research, describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to suppress an essential anticancer immune response.

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Drug Resistance, Breast Cancer, Cancer Diagnosis, Microscopy, Cancer Research

A Swell Diagnostic Method

Ludwig researchers show how a method that physically expands tissues can improve early breast cancer diagnostics and extend the capabilities of ordinary pathology labs

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ASCO 2017, ASCO, Immunotheapy, Immunotherapy Clinical Trials, ASCO Annual Meeting

Ludwig Researchers Present New Findings on Combination Immunotherapy and Other Research at the 2017 ASCO Annual Meeting

Ludwig Cancer Research released today the full scope of Ludwig’s participation at this year’s American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, June 2-6.

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Brain Cancer, Gliobastoma, PTEN

Ludwig Researchers Identify Counterintuitive Approach to Treating a Brain Cancer

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The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, Ludwig researchers have shown that one way to override the growth-promoting effects of PTEN deletion is, surprisingly, to inhibit a separate tumor suppressor gene.







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