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Article ID: 689731

New Imaging Technology May Help Predict Aggressiveness of Lung Cancer

Case Western Reserve University

Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease.

Released:
16-Feb-2018 2:05 PM EST
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Cancer, Technology, Local - Ohio

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Article ID: 689549

Living Human Tracheas

Case Western Reserve University

Biomedical engineers at Case Western Reserve University in Cleveland, Ohio, and Worcester Polytechnic Institute in Worcester, Mass. are growing tracheas by coaxing cells to form three distinct tissue types after assembling them into a tube structure-without relying on scaffolding strategies currently being investigated by other groups.

Released:
14-Feb-2018 2:05 PM EST
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All Journal News, Cardiovascular Health, Engineering, Local - Ohio

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Article ID: 689448

Investigators Highlight Potential of Exercise in Addressing Substance Abuse in Teens

Case Western Reserve University

Exercise has numerous, well-documented health benefits. Could it also play a role in preventing and reducing substance misuse and abuse in adolescents? This is the intriguing question that a team of investigators from Case Western Reserve University School of Medicine and Cleveland Clinic seeks to answer. In a review article recently published in Birth Defects Research, the trio of researchers supplies a rationale for the use of exercise, particularly assisted exercise, in the prevention and adjunctive treatment of substance-use disorders – including alcohol, marijuana, cocaine, opioids, and heroin.

Released:
13-Feb-2018 10:05 AM EST
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Article ID: 689363

Researchers Inhibit Cancer Metastases via Novel Steps

Case Western Reserve University

In one of the first successes of its kind, researchers have inhibited the spreading of cancer cells from one part of the body to another. In doing so, they relied on a new model of how cancer metastasizes that emphasizes epigenetics, which examines how genes are turned on and off.

Released:
12-Feb-2018 11:05 AM EST
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Article ID: 689155

Challenging Core Belief: Have We Misunderstood How Earth's Solid Center Formed?

Case Western Reserve University

A research team at Case Western Reserve is asking an important question about the self-evident paradox standing in the way of our generally accepted theory of how the Earth's inner core formed. The "inner core nucleation paradox" suggests that there is now satisfactory solution to account for the existence of a solid inner core. So, now what?

Released:
7-Feb-2018 12:05 PM EST
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Geology, Particle Physics, Physics, Space, Local - Ohio, All Journal News

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Article ID: 689053

Full-Length Serotonin Receptor Structure Seen for First Time

Case Western Reserve University

A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full length serotonin receptors for the first time. The tiny proteins—approximately a billionth of a meter long—are common drug targets, despite limited available information about their structure. Now, new images published in Nature Communications provide snapshots of the receptors, including details about molecular binding sites that could lead to more precise drug design.

Released:
6-Feb-2018 11:05 AM EST
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Article ID: 688599

Researchers Reverse Symptoms in Neurologic Disease Model

Case Western Reserve University

It is a parent’s nightmare: a child is born apparently healthy, then stops meeting developmental milestones at one year old. Her verbal and motor skills vanish, and irregular breathing, seizures, and a host of other problems appear. The cause is Rett syndrome—a devastating genetic, neurologic disorder that typically affects girls, resulting in severe disability and often accompanied by autistic behavior. Most Rett patients will live into middle age and require specialized full-time care. There is no cure, but researchers from Case Western Reserve University School of Medicine have been working to find ways to restore brain function and reverse disabilities associated with Rett syndrome.

Released:
29-Jan-2018 11:05 AM EST
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Article ID: 688588

Researchers Receive $6.5 Million NIH Grant to Use Big Data to Tackle Psoriasis

Case Western Reserve University

An experienced interdisciplinary team of psoriasis and computational researchers from Case Western Reserve University School of Medicine (CWRU SOM) and University Hospitals Cleveland Medical Center (UHCMC) has received a $6.5M, 5-year grant from the National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS). The grant supports a Center of Research Translation in Psoriasis (CORT) at CWRU and UHCMC.

Released:
29-Jan-2018 10:05 AM EST
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Article ID: 688476

Alex Huang, MD, PhD, Receives $450,000 from Pediatric Cancer Research Foundation

Case Western Reserve University

Leading cancer researcher, Alex Huang MD, PhD, has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma.

Released:
25-Jan-2018 10:05 AM EST
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Article ID: 688279

Researchers Borrow from AIDS Playbook to Tackle Rheumatic Heart Disease: Taking Services to the People

Case Western Reserve University

Billions of US taxpayer dollars have been invested in Africa over the past 15 years to improve care for millions suffering from the HIV/AIDS epidemic; yet health systems on the continent continue to struggle. What if the investments and lessons learned from HIV could be used to improve care for those with other serious chronic conditions? With this question in mind, researchers from Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, along with investigators and clinicians based in Uganda, borrowed an HIV/AIDS innovation to seek inroads against rheumatic heart disease in sub-Saharan Africa.

Released:
22-Jan-2018 2:55 PM EST
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