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Beth Israel Deaconess Medical Center, Maratos-Flier

Research Reveals Potential Target for Alcohol Liver Disease

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BOSTON - Drinking too much alcohol can damage the liver, but investigators have discovered a protective response in the organ that might be targeted to help treat alcoholic liver disease. The team - led by researchers at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with colleagues at the University of Pennsylvania - also found that the same protective response may be involved in aversion to alcohol and could therefore help in the treatment of alcoholism.

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Weight, Appetite Control, Diabetes, Endocrinology, Brain, Insula, Walnuts, Satiety, fMRI

In a Nutshell: Walnuts Activate Brain Region Involved in Appetite Control

Packed with nutrients linked to better health, walnuts are also thought to discourage overeating by promoting feelings of fullness. Now, in a new brain imaging study, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that consuming walnuts activates an area in the brain associated with regulating hunger and cravings. The findings, published online in the journal Diabetes, Obesity and Metabolism, reveal for the first time the neurocognitive impact these nuts have on the brain.

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Opioid, Beth Israel Deaconess Medical Center, Harvard Medical School

Study Finds Stark Increase in Opioid-Related Admissions, Deaths in Nation’s ICUs

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Since 2009, hospital intensive care units have witnessed a stark increase in opioid-related admissions and deaths, according to new study led by researchers at Beth Israel Deaconess Medical Center's (BIDMC) Center for Healthcare Delivery Science. Published online today ahead of print in the Annals of the American Thoracic Society, the study is believed to be the first to quantify the impact of opioid abuse on critical care resources in the United States.

Medicine

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OpenNotes, open notes, health transformation, health information technolgy, Patient Engagement, Patient Safety

What Patients Value About Access to Their Visit Notes

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New findings from researchers at OpenNotes and Beth Israel Deaconess Medical Center shed light on what patients value about having access to their visit notes and being invited to participate more actively in the safety of their care.

Medicine

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Pathology, Expansion, Precancerous, Breast, Breast Cancer, Lesions, precancerous le, Kidney Disease, minimal change disease, Podocyte, light microscopy, scanning electron microscope

New Way to Enlarge Tissues Gives Pathologists a Closer Look at Cells

Investigators from Beth Israel Deaconess Medical Center and the Massachusetts Institute of Technology have developed and tested an innovative, reliable means of analyzing pre-cancerous breast lesions diagnosing certain kidney diseases and using only a conventional light microscope. The technique – dubbed “expansion pathology or ExPath – enhances pathologists’ diagnostic ability and could mean earlier interventions for high-risk patients. The research team describes their joint effort in a paper published today in the journal Nature Biotechnology.

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Medicare, Beth Israel Deaconess Medical Center, Robert Yeh, Hospital Readmissions

Analysis of Hospital Readmissions of All Ages, Insurance Types Identifies High Risk Groups

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First-of-its-kind study looks beyond Medicare readmission rates to determine causes of short-term readmissions of patients across the spectrum of age and insurance types. While Medicare patients account for more than half of all readmissions, readmission rates of non-Medicare patients were still significant and costly. Psychiatric disease and substance abuse were the most common diagnoses leading to readmission among non-elderly patients, highlighting the need for targeted interventions.

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Bidmc, Beth Israel Deaconess Medical Center, photophobia, Parasympathetic, Sympathetic, Emotions, Colors, Migraine

Study: Exposure to Light Causes Emotional and Physical Responses in Migraine Sufferers

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This research found that light makes migraine headaches more painful and induces negative emotions and unpleasant physical sensations. Laboratory studies identify previously unknown connections between nerve cells in the eye and neurons in the brain that regulate physiological, autonomic, endocrine and emotional responses. These findings offer promising path forward for researchers in treatment of migraines.

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Alzheimber's Disease, Beth Israel Deaconess Medical Center, Neuroscience

Anti-Epilepsy Drug Restores Normal Brain Activity in Mild Alzheimer’s Disease

In a recent feasibility study, BIDMC tested an anti-epileptic drug for its potential impact on the brain activity of patients with mild Alzheimer’s disease. The team documented changes in patients’ EEGs that suggest the drug could have a beneficial effect.

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Scientists Reveal a Key Link Between Brain Circuits Governing Hunger and Cravings

By developing a new approach to imaging and manipulating particular groups of neurons in the mouse brain, scientists at Beth Israel Deaconess Medical Center (BIDMC) have identified a pathway by which neurons governing feelings of hunger influence distant neurons involved in the decision of whether or not to react to food-related cues. Their findings could open the door to targeted therapies that dampen food cue-evoked cravings in people with obesity. The research was published online today in the journal Nature.

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Dermatology, Chronic plaque psoriasis , Beth Israel Deaconess Medical Center, Alexa Kimball, tildrakizumab

Promising New Treatment Option for Chronic Plaque Psoriasis

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The study tested the efficacy of tildrakizumab, an antibody that targets only a very specific immune system pathway. More than 60 percent of all patients who received the active medication showed improvement, compared to less than 10 percent of patients who received placebos.







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