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Beth Israel Deaconess Medical Center

Like a Baby: The Vicious Cycle of Childhood Obesity and Snoring

Poor nutrition and lack of exercise lead to the increasing prevalence of obesity which, in turn, is the major predictor of diabetes and future risk of cardiovascular disease in western societies. Excess weight is also closely associated with obstructive sleep apnea (OSA), the increasingly common and potentially serious sleep disorder that is often marked by loud snoring. OSA affects about 5 to 10 percent of children 8 to 11 years old. While evidence suggests that OSA appears to exacerbate obesity and its comorbidities such as diabetes and cardiovascular disease, its effects on children have not yet been studied in detail.

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Beth Israel Deaconess Medical Center, clifford b. saper, Sleep Apnea, SIDS

Sleeping Through the Snoring: Researchers ID Neurons That Rouse the Brain to Breathe

A common and potentially serious sleep disorder, obstructive sleep apnea affects at least one quarter of U.S. adults and is linked to increased risk of diabetes, obesity and cardiovascular disease. In a paper published today in the journal Neuron, researchers at Beth Israel Deaconess Medical Center (BIDMC) identified specific neural circuitry responsible for rousing the brain of mice in simulated apnea conditions. The findings could lead to potential new drug therapies to help patients with obstructive sleep apnea get more rest.

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Beth Israel Deaconess Medical Center, Maternal Health, Philip E. Hess

Study Shows Epidurals Don’t Slow Labor

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Research led by scientists at Beth Israel Deaconess Medical Center (BIDMC) demonstrated that epidural medication had no effect on the duration of the second stage of labor, normal vaginal delivery rate, incidence of episiotomy, the position of the fetus at birth or any other measure of fetal well-being the researchers investigated. The study compared the effects of catheter-infused, low-concentration epidural anesthetic to a catheter-infused saline placebo in this double-blinded, randomized trial of 400 women.

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IBD, Crohn's Disease, Beth Israel Deaconess Medical Center, Adam S. Cheifetz, MD, Infliximab, Ulcerative Colitis

IBD Patients May Stay Healthier When Doctors Monitor Medications Before They Lose Efficacy

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Proactive monitoring of blood levels of the therapeutic drug infliximab was associated with improved outcomes including lower risk of surgery and hospitalization.

Medicine

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Beth Israel Deaconess Medical Center, Maratos-Flier

Research Reveals Potential Target for Alcohol Liver Disease

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BOSTON - Drinking too much alcohol can damage the liver, but investigators have discovered a protective response in the organ that might be targeted to help treat alcoholic liver disease. The team - led by researchers at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with colleagues at the University of Pennsylvania - also found that the same protective response may be involved in aversion to alcohol and could therefore help in the treatment of alcoholism.

Medicine

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Weight, Appetite Control, Diabetes, Endocrinology, Brain, Insula, Walnuts, Satiety, fMRI

In a Nutshell: Walnuts Activate Brain Region Involved in Appetite Control

Packed with nutrients linked to better health, walnuts are also thought to discourage overeating by promoting feelings of fullness. Now, in a new brain imaging study, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that consuming walnuts activates an area in the brain associated with regulating hunger and cravings. The findings, published online in the journal Diabetes, Obesity and Metabolism, reveal for the first time the neurocognitive impact these nuts have on the brain.

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Opioid, Beth Israel Deaconess Medical Center, Harvard Medical School

Study Finds Stark Increase in Opioid-Related Admissions, Deaths in Nation’s ICUs

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Since 2009, hospital intensive care units have witnessed a stark increase in opioid-related admissions and deaths, according to new study led by researchers at Beth Israel Deaconess Medical Center's (BIDMC) Center for Healthcare Delivery Science. Published online today ahead of print in the Annals of the American Thoracic Society, the study is believed to be the first to quantify the impact of opioid abuse on critical care resources in the United States.

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OpenNotes, open notes, health transformation, health information technolgy, Patient Engagement, Patient Safety

What Patients Value About Access to Their Visit Notes

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New findings from researchers at OpenNotes and Beth Israel Deaconess Medical Center shed light on what patients value about having access to their visit notes and being invited to participate more actively in the safety of their care.

Medicine

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Pathology, Expansion, Precancerous, Breast, Breast Cancer, Lesions, precancerous le, Kidney Disease, minimal change disease, Podocyte, light microscopy, scanning electron microscope

New Way to Enlarge Tissues Gives Pathologists a Closer Look at Cells

Investigators from Beth Israel Deaconess Medical Center and the Massachusetts Institute of Technology have developed and tested an innovative, reliable means of analyzing pre-cancerous breast lesions diagnosing certain kidney diseases and using only a conventional light microscope. The technique – dubbed “expansion pathology or ExPath – enhances pathologists’ diagnostic ability and could mean earlier interventions for high-risk patients. The research team describes their joint effort in a paper published today in the journal Nature Biotechnology.

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Medicare, Beth Israel Deaconess Medical Center, Robert Yeh, Hospital Readmissions

Analysis of Hospital Readmissions of All Ages, Insurance Types Identifies High Risk Groups

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First-of-its-kind study looks beyond Medicare readmission rates to determine causes of short-term readmissions of patients across the spectrum of age and insurance types. While Medicare patients account for more than half of all readmissions, readmission rates of non-Medicare patients were still significant and costly. Psychiatric disease and substance abuse were the most common diagnoses leading to readmission among non-elderly patients, highlighting the need for targeted interventions.







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