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Merger, Sensory, Health, Taste, Smell, Innovation

Jefferson and Monell Center Sign Letter of Intent to Merge

Leadership at Jefferson and the Monell Center announced today the signing of a non-binding Letter of Intent (LOI) to move forward with discussions of merging the two organizations.

Science

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Gene Expression Profile, calcium imaging, single-cell genomics, RNA-Seq technology, sweet taste, salt taste, umami taste, Bioinformatics

A Taste Cell Encyclopedia

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A significant technological advance from the Monell Center now allows scientists to identify the complete set of genes in any type of taste receptor cell. The technology will help identify precisely how each cell carries out its specific function.

Science

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taste regeneration, Signaling Pathway, Organoids, taste cell differentiation, RNA-Seq technology, taste stem cell

Bitter or Sweet? How Taste Cells Decide What They Want to Be

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A new study from the Monell Center and collaborating institutions advances understanding of how stem cells on the tongue grow into the different types of mature taste cells that detect either sweet, salty, sour, bitter, or umami. The findings may someday allow scientists to treat taste disorders, characterize new taste qualities, or even fine-tune a person’s taste perception to encourage healthier eating.

Medicine

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School Lunchroom Perfect Place to Teach Kids to Like and Eat Heathy Foods

Medicine

Life

Social and Behavioral Sciences

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Anosmia, Social Network, olfactory dysfunction, social life, Aging, Sex And Gender Differences

The Social Costs of Smell Loss in Older Women

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A new study of older U.S. adults from the Monell Center and collaborating institutions reports that a woman’s social life is associated with how well her sense of smell functions. The study found that older women who do less well on a smell identification task also tend to have fewer social connections.

Medicine

Channels:

TMAU, rare disease, exome sequencing, fish odor, Sensory Evaluation, FMO3, Body Odor

Potential New Causes for the Odor-Producing Disorder TMAU

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A study from the Monell Center and collaborators provides new insight into the causes of trimethylaminura (TMAU), a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish. Previously attributed solely to mutations in the FMO3 gene, the study identifies additional genes that may contribute to TMAU. The findings indicate that genetic testing to identify FMO3 mutations may not be sufficient to identify all underlying causes of TMAU.

Medicine

Channels:

ovarian cancer research, cancer diagnostic, analytical chemistry, Nanosensor, enose, Multidisciplinary, odor profile

Monell Center Receives Grant to Characterize Distinctive Odor of Ovarian Cancer

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A new grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation will allow Monell scientists and collaborators to confirm initial findings of a unique odor pattern for ovarian cancer. The multi-disciplinary team will use the information to customize a portable screening device that can diagnose the deadly disease at early, treatable stages.

Life

Social and Behavioral Sciences

Channels:

Multisensory Integration, Children, Olfaction, Odors, affective matching, Social Development, National Learning Laboratory, museum studies, Autism Spectrum Disorder

Via Eyes or Noses? How Young Children Use Sensory Cues to Guide Social Decisions

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New research from the Monell Center reveals that children begin using olfactory information to help guide their responses to emotionally-expressive faces at about age five. The findings advance understanding of how children integrate different types of sensory information to direct their social behavior.

Medicine

Channels:

palatability, Taste, Obesity, nonnutritive , Artificial Sweetener, mineral oil, Food Choice, sweet taste, cafeteria diet, Overeating

Does Good-Tasting Food Cause Weight Gain?

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Does eating good-tasting food make you gain weight? Despite the common perception that good-tasting food is unhealthy and causes obesity, new research from the Monell Center using a mouse model suggests that desirable taste in and of itself does not lead to weight gain.

Science

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Gates Foundation, Grant Award, Taste, pharmaceutical compliance, Children, Bitter Taste Sensitivity, parasitic infections, Schistosomiasis, recurrent diarrhea, sensory science, taste cells, screening assays, develolping nations, Pharmaceuticals, Interdisciplinary Research, taste blockers

Monell Center Receives Funding to Develop Technologies to Improve Taste of Lifesaving Drugs

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The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."







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