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Article ID: 696450

Turning A Phage

University of California San Diego Health

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America’s first Center for Innovative Phage Applications and Therapeutics (IPATH).

Released:
21-Jun-2018 10:05 AM EDT
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Article ID: 696177

Greater Levels of Vitamin D Associated with Decreasing Risk of Breast Cancer

University of California San Diego Health

Researchers at University of California San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast cancer. Their epidemiological study is published in the June 15 online issue of PLOS ONE, in collaboration with Creighton University, Medical University of South Carolina and GrassrootsHealth, an Encinitas-based nonprofit organization that promotes vitamin D research and its therapeutic benefits.

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15-Jun-2018 2:00 PM EDT
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Article ID: 696074

UC San Diego Launches New Center for Anti-Parasitic Drug Discovery and Development

University of California San Diego Health

Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the University of California San Diego has now launched a new Center for Anti-Parasitic Drug Discovery and Development to address this unmet need in global health.

Released:
13-Jun-2018 1:05 PM EDT
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Article ID: 696006

Composition of Complex Sugars in Breast Milk May Prevent Future Food Allergies

University of California San Diego Health

The unique composition of a mother’s breastmilk may help to reduce food sensitization in her infant, report researchers at the University of California San Diego School of Medicine with colleagues in Canada.

Released:
12-Jun-2018 11:05 AM EDT
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Article ID: 695810

Rohit Loomba, MD, @UCSDHealth liver expert on NASH and the First International NASH Day

University of California San Diego Health

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7-Jun-2018 4:05 PM EDT
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Article ID: 695724

What’s Inside Your Medical Record?

University of California San Diego Health

Patients at UC San Diego Health can now read the medical notes signed by their primary care physician. This move toward transparency is part of an international trend to make patients feel more in control of their health care.

Released:
6-Jun-2018 3:05 PM EDT
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Article ID: 695707

Antibody Blocks Inflammation, Protects Mice from Hardened Arteries and Liver Disease

University of California San Diego Health

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged their lives.

Released:
6-Jun-2018 1:05 PM EDT
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  • Embargo expired:
    1-Jun-2018 11:00 AM EDT

Article ID: 695305

Phase I Trial Finds Experimental Drug Safe in Treating Chronic Lymphocytic Leukemia

University of California San Diego Health

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.

Released:
30-May-2018 1:05 PM EDT
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    1-Jun-2018 11:00 AM EDT

Article ID: 695234

Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results

University of California San Diego Health

Researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.

Released:
29-May-2018 1:05 PM EDT
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  • Embargo expired:
    29-May-2018 11:00 AM EDT

Article ID: 695119

Single Injection Alleviates Chemotherapy Pain for Months in Mice

University of California San Diego Health

UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.

Released:
24-May-2018 4:05 PM EDT
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