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21-Oct-2016 1:05 PM EDT
Providing Interventions During Pregnancy and After Birth to Support Breastfeeding Recommended
JAMA - Journal of the American Medical Association

The U.S. Preventive Services Task Force (USPSTF) recommends providing interventions during pregnancy and after birth to support breastfeeding. The report appears in the October 25 issue of JAMA.

14-Oct-2016 2:05 PM EDT
Study Examines Work Status, Productivity After Bariatric Surgery
JAMA - Journal of the American Medical Association

In a study appearing in the October 18 issue of JAMA, David R. Flum, M.D., M.P.H., of the University of Washington, Seattle, and colleagues assessed working status and change in productivity in the first 3 years following bariatric surgery for severe obesity.

14-Oct-2016 2:05 PM EDT
Study Finds Mixed Results for Use of Mesh for Hernia Repair
JAMA - Journal of the American Medical Association

Among patients undergoing incisional hernia repair, the use of mesh to reinforce the repair was associated with a lower risk of hernia recurrence over 5 years compared with when mesh was not used, although with long-term follow-up, the benefits attributable to mesh were offset in part by mesh-related complications, according to a study published online by JAMA. The study is being released to coincide with its presentation at the American College of Surgeons Clinical Congress 2016.

30-Sep-2016 3:05 PM EDT
Use of Therapeutic Hypothermia and Outcomes Following in-Hospital Cardiac Arrest
JAMA - Journal of the American Medical Association

In a study appearing in the October 4 issue of JAMA, Paul S. Chan, M.D., of Saint Luke's Mid America Heart Institute, Kansas City, and colleagues evaluated the association of hypothermia treatment with survival to hospital discharge and with favorable neurological survival at hospital discharge among patients with in-hospital cardiac arrest.

30-Sep-2016 3:05 PM EDT
Certain LDL-C-Lowering Genetic Variants Associated with Higher Risk of Type 2 Diabetes
JAMA - Journal of the American Medical Association

In a study appearing in the October 4 issue of JAMA, Luca A. Lotta, M.D., Ph.D., of the University of Cambridge, U.K., and colleagues examined the associations with type 2 diabetes and coronary artery disease of low-density lipoprotein cholesterol (LDL-C)-lowering genetic variants.

30-Sep-2016 3:05 PM EDT
Study Compares Treatments for Urinary Incontinence in Women
JAMA - Journal of the American Medical Association

In a study appearing in the October 4 issue of JAMA, Cindy L. Amundsen, M.D., of Duke University, Durham, N.C., and colleagues assessed whether injection of onabotulinumtoxinA (Botox A) is superior to sacral neuromodulation (use of an implanted electrode for bladder control) in controlling episodes of refractory urgency urinary incontinence in women.

23-Sep-2016 11:05 AM EDT
Study Compares CV Risk Reduction of Statin vs Nonstatin Therapies Used for Lowering LDL-C
JAMA - Journal of the American Medical Association

In a study appearing in the September 27 issue of JAMA, Marc S. Sabatine, M.D., M.P.H., of Brigham and Women's Hospital, Harvard Medical School, Boston, and colleagues evaluated the association between lowering low-density lipoprotein cholesterol (LDL-C) and relative cardiovascular risk reduction across different statin and nonstatin therapies.

23-Sep-2016 11:05 AM EDT
Earlier Treatment with Surgery to Remove Blood Clot Linked with Less Disability Following Stroke
JAMA - Journal of the American Medical Association

In an analysis that included nearly 1,300 patients with large-vessel ischemic stroke, earlier treatment with endovascular thrombectomy (intra-arterial use of a micro-catheter or other device to remove a blood clot) plus medical therapy (use of a clot dissolving agent) compared with medical therapy alone was associated with less disability at 3 months, according to a study appearing in the September 27 issue of JAMA.

23-Sep-2016 11:05 AM EDT
Single-Blind vs Double-Blind Peer Review and Effect of Author Prestige
JAMA - Journal of the American Medical Association

In a study appearing in the September 27 issue of JAMA, Kanu Okike, M.D., M.P.H., of the Kaiser Moanalua Medical Center, Honolulu, and colleagues examined if bias with single-blind peer review might be greatest in the setting of author or institutional prestige.

9-Sep-2016 12:05 PM EDT
New Set of Recommendations Developed to Improve Quality of Cost-Effectiveness Analyses
JAMA - Journal of the American Medical Association

The Second Panel on Cost-Effectiveness in Health and Medicine reviewed the current status of the field of cost-effectiveness analysis and developed a new set of recommendations, with major changes including the recommendation to perform analyses from 2 reference case perspectives and to provide an impact inventory to clarify included consequences, according to an article appearing in the September 13 issue of JAMA.

9-Sep-2016 12:05 PM EDT
Study Examines Survival Outcomes after Different Lung Cancer Staging Methods
JAMA - Journal of the American Medical Association

In a study appearing in the September 13 issue of JAMA, Jouke T. Annema, M.D., Ph.D., of the Academic Medical Center, Amsterdam, and colleagues examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung cancer.

9-Sep-2016 12:05 PM EDT
Risk Factors and Clinical Outcomes of Infective Endocarditis After Transcatheter Aortic Valve Replacement
JAMA - Journal of the American Medical Association

Among patients undergoing transcatheter aortic valve replacement, younger age, male sex, history of diabetes mellitus, and moderate to severe residual aortic regurgitation were significantly associated with an increased risk of infective endocarditis, and patients who developed endocarditis had high rates of in-hospital mortality and 2-year mortality, according to a study appearing in the September 13 issue of JAMA.

9-Sep-2016 12:05 PM EDT
Implementation of Value-Driven Outcomes Program Linked With Reduced Costs, Improved Quality
JAMA - Journal of the American Medical Association

Implementing an analytic tool that allocates clinical care costs and quality measures to individual patient encounters was associated with significant improvements in value of care for 3 designated outcomes—total joint replacement, laboratory testing among medical inpatients, and sepsis management, according to a study appearing in the September 13 issue of JAMA.

2-Sep-2016 11:05 AM EDT
Nasal Sprays Not Effective in Reducing Duration, Frequency of Nosebleeds Caused by Blood Vessel Disorder
JAMA - Journal of the American Medical Association

Two studies appearing in the September 6 issue of JAMA examine the effectiveness of nasal sprays to reduce the frequency and duration of nosebleeds caused by hereditary hemorrhagic telangiectasia.

2-Sep-2016 11:05 AM EDT
Screening for Latent Tuberculosis Infection Recommended for Those at Increased Risk
JAMA - Journal of the American Medical Association

The U.S. Preventive Services Task Force (USPSTF) recommends screening for latent tuberculosis infection in populations at increased risk. The report appears in the September 6 issue of JAMA.

2-Sep-2016 11:05 AM EDT
MRIs During Pregnancy and Outcomes for Infants, Children
JAMA - Journal of the American Medical Association

Exposure to magnetic resonance imaging (MRI) during the first trimester of pregnancy compared with nonexposure was not associated with increased risk of harm to the fetus or in early childhood, according to a study appearing in the September 6 issue of JAMA.

2-Sep-2016 11:05 AM EDT
Findings Suggest Electric Fan Use by Elderly During Extreme Heat Could Be Harmful
JAMA - Journal of the American Medical Association

In a study appearing in the September 6 issue of JAMA, Craig G. Crandall, Ph.D., of the University of Texas Southwestern Medical Center, Dallas, and colleagues examined whether electric fan use would delay elevations in heart rate and core temperature of elderly adults exposed to extreme heat and humidity.

4-Aug-2016 4:05 PM EDT
Overall Prevalence of Diabetic Kidney Disease Does Not Change Significantly in U.S.
JAMA - Journal of the American Medical Association

Among U.S. adults with diabetes from 1988 to 2014, the overall prevalence of diabetic kidney disease did not change significantly, while the prevalence of albuminuria declined and the prevalence of reduced estimated glomerular filtration rate increased, according to a study appearing in the August 9 issue of JAMA.

4-Aug-2016 4:05 PM EDT
Device Reduces Risk of Brain Injury after Heart Valve Replacement
JAMA - Journal of the American Medical Association

Among patients with severe aortic stenosis (narrowing of the aortic valve) undergoing transcatheter aortic valve implantation, the use of a cerebral protection device (a filter that captures debris [tissue and plaque] dislodged during the procedure) reduced the number and volume of brain lesions, according to a study appearing in the August 9 issue of JAMA.

4-Aug-2016 4:05 PM EDT
Most Patients Taking Warfarin Long-Term Do Not Maintain Stable INR Values
JAMA - Journal of the American Medical Association

In a study appearing in the August 9 issue of JAMA, Sean D. Pokorney, M.D., M.B.A., Eric D. Peterson, M.D., M.P.H., of Duke University Medical Center, Durham, N.C., and colleagues examined whether patients receiving warfarin who have stable international normalized ratio (INR) values remain stable over time.

22-Jul-2016 11:05 AM EDT
Study Compares Cognitive Outcomes for Treatments of Brain Lesions
JAMA - Journal of the American Medical Association

Among patients with 1 to 3 brain metastases, the use of stereotactic radiosurgery (SRS) alone, compared with SRS combined with whole brain radiotherapy, resulted in less cognitive deterioration at 3 months, according to a study appearing in the July 26 issue of JAMA.

22-Jul-2016 11:05 AM EDT
Survival, Surgical Interventions for Children with Rare, Genetic Birth Disorder
JAMA - Journal of the American Medical Association

Among children born with the chromosome disorders trisomy 13 or 18 in Ontario, Canada, early death was the most common outcome, but 10 percent to 13 percent survived for 10 years, according to a study appearing in the July 26 issue of JAMA.

22-Jul-2016 11:05 AM EDT
Late Preterm, Early Term Birth Rates and Link with Clinician-Initiated Obstetric Interventions
JAMA - Journal of the American Medical Association

Between 2006 and 2014, late preterm and early term birth rates decreased in the United States and an association was observed between early term birth rates and decreasing clinician-initiated obstetric interventions, according to a study appearing in the July 26 issue of JAMA.

10-Jul-2016 10:05 PM EDT
Risk of HIV Transmission From Condomless Sex with Virologically Suppressed HIV-Infected Individuals
JAMA - Journal of the American Medical Association

Among nearly 900 serodifferent (one partner is HIV-positive, one is HIV-negative) heterosexual and men who have sex with men couples in which the HIV-positive partner was using suppressive antiretroviral therapy and who reported condomless sex, during a median follow-up of 1.3 years per couple, there were no documented cases of within-couple HIV transmission, according to a study appearing in the July 12 issue of JAMA, an HIV/AIDS theme issue.

10-Jul-2016 10:05 PM EDT
2016 Recommendations for Antiretroviral Drugs for the Treatment and Prevention of HIV Infection in Adults
JAMA - Journal of the American Medical Association

In a report appearing in the July 12 issue of JAMA, an HIV/AIDS theme issue, Huldrych F. Gunthard, M.D., of University Hospital Zurich, Switzerland, and colleagues with the International Antiviral Society-USA panel, updated recommendations for the use of antiretroviral therapy in adults with established HIV infection, including when to start treatment, initial regimens, and changing regimens, along with recommendations for using antiretroviral drugs for preventing HIV among those at risk, including preexposure and postexposure prevention.

10-Jul-2016 10:05 PM EDT
Interventions Do Not Improve Viral Suppression Among Hospitalized Patients with HIV Infection and Substance Use
JAMA - Journal of the American Medical Association

In a study appearing in the July 12 issue of JAMA, an HIV/AIDS theme issue, Lisa R. Metsch, Ph.D., of Columbia University, New York, and colleagues assessed the effect of structured patient navigation (care coordination with case management) interventions with or without financial incentives to improve HIV-l viral suppression rates among hospitalized patients with elevated HIV-1 viral loads and substance use.

10-Jul-2016 10:05 PM EDT
Caregiver Assistance Increases Among Home-Dwelling Functionally Disabled Older Adults
JAMA - Journal of the American Medical Association

In a study appearing in the July 12 issue of JAMA, Claire K. Ankuda, M.D., M.P.H., and Deborah A. Levine, M.D., M.P.H., of the University of Michigan, Ann Arbor, examined trends in caregiving for home-dwelling older adults with functional disability.

1-Jul-2016 3:05 PM EDT
Euthanasia and Physician-Assisted Suicide Increasingly Being Legalized, Although Still Relatively Uncommon
JAMA - Journal of the American Medical Association

Euthanasia and physician-assisted suicide in the United States, Canada, and Europe are increasingly being legalized, but they remain relatively rare, and primarily involve patients with cancer, according to a study appearing in the July 5 issue of JAMA.

1-Jul-2016 3:05 PM EDT
Drug Helps Control Involuntary, Sudden Movements of Huntington Disease
JAMA - Journal of the American Medical Association

In a study appearing in the July 5 issue of JAMA, Samuel Frank, M.D., of Harvard Medical School, Boston, and the Huntington Study Group, and colleagues evaluated the efficacy and safety of the drug deutetrabenazine to control a prominent symptom of Huntington disease, chorea, which is an involuntary, sudden movement that can affect any muscle and flow randomly across body regions. Chorea can interfere with daily functioning and increase the risk of injury.

1-Jul-2016 3:05 PM EDT
No Association Found Between Contrast Agents Used for MRIs and Nervous System Disorder
JAMA - Journal of the American Medical Association

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

1-Jul-2016 3:05 PM EDT
Effect of Palliative Care-Led Meetings for Families of Patients with Chronic Critical Illness
JAMA - Journal of the American Medical Association

Among families of patients with chronic critical illness, the use of palliative care-led informational and emotional support meetings compared with usual care did not reduce anxiety or depression symptoms, according to a study appearing in the July 5 issue of JAMA.

18-Jun-2016 1:05 PM EDT
Study Finds Decrease in Uninsured Hospital Patients, Increase in Those with Medicaid
JAMA - Journal of the American Medical Association

In a study appearing in the June 21 issue of JAMA, Matthew M. Davis, M.D., M.A.P.P., of the University of Michigan, Ann Arbor, and colleagues examined changes in insurance coverage among hospitalized nonelderly adults after Michigan expanded Medicaid coverage in 2014 under the Affordable Care Act (ACA).

18-Jun-2016 12:05 PM EDT
Improvement Seen in U.S. Diet
JAMA - Journal of the American Medical Association

In nationally representative surveys conducted between 1999 and 2012, several improvements in self-reported dietary habits were identified, such as increased consumption of whole grains, with additional findings suggesting persistent or worsening disparities based on race/ethnicity and education and income level, according to a study appearing in the June 21 issue of JAMA.

18-Jun-2016 1:05 PM EDT
Protein-Based Risk Score May Help Predict CV Events Among Patients with Heart Disease
JAMA - Journal of the American Medical Association

In a study appearing in the June 21 issue of JAMA, Peter Ganz, M.D., of the University of California-San Francisco, and colleagues conducted a study to develop and validate a score to predict risk of cardiovascular outcomes among patients with coronary heart disease using analysis of circulating proteins.

18-Jun-2016 12:05 PM EDT
Some Plant-Based Therapies Associated with Modest Improvement in Menopausal Symptoms
JAMA - Journal of the American Medical Association

An analysis of more than 60 studies suggests that some plant-based therapies are associated with modest reductions in the frequency of hot flashes and vaginal dryness but no significant reduction in night sweats, according to a study appearing in the June 21 issue of JAMA.

2-Jun-2016 3:05 PM EDT
Prevalence of Obesity in the U.S. Increases Among Women, but Not Men
JAMA - Journal of the American Medical Association

The prevalence of obesity in 2013- 2014 was 35 percent among men and 40 percent among women, and between 2005 and 2014, there was an increase in prevalence among women, but not men, according to a study appearing in the June 7 issue of JAMA.

2-Jun-2016 3:05 PM EDT
Screening for Syphilis Recommended for Persons at Increased Risk of Infection
JAMA - Journal of the American Medical Association

The U.S. Preventive Services Task Force (USPSTF) has found convincing evidence that screening for syphilis infection in asymptomatic, nonpregnant persons at increased risk for infection provides substantial benefit. The report appears in the June 7 issue of JAMA.

2-Jun-2016 3:05 PM EDT
Findings Suggest Small Increase in Obesity Among U.S. Teens in Recent Years
JAMA - Journal of the American Medical Association

Among U.S. children and adolescents 2 to 19 years of age, the prevalence of obesity in 2011- 2014 was 17 percent, and over approximately the last 25 years, the prevalence has decreased in children age 2 to 5 years, leveled off in children 6 to 11 years, and increased among adolescents 12 to 19 years of age, according to a study appearing in the June 7 issue of JAMA.

20-May-2016 12:05 PM EDT
Higher Salt Intake May Increase Risk of CVD among Patients with Chronic Kidney Disease
JAMA - Journal of the American Medical Association

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

20-May-2016 12:05 PM EDT
Antidepressants Commonly and Increasingly Prescribed for Nondepressive Indications
JAMA - Journal of the American Medical Association

In a study appearing in the May 24/31 issue of JAMA, Jenna Wong, M.Sc., of McGill University, Montreal, Canada, and colleagues analyzed treatment indications for antidepressants and assessed trends in antidepressant prescribing for depression.

20-May-2016 12:05 PM EDT
Rates of Obesity, Diabetes Lower in Neighborhoods That Are More Walkable
JAMA - Journal of the American Medical Association

Urban neighborhoods in Ontario, Canada, that were characterized by more walkable design were associated with decreased prevalence of overweight and obesity and decreased incidence of diabetes between 2001 and 2012, according to a study appearing in the May 24/31 issue of JAMA.

6-May-2016 11:05 AM EDT
Increase Seen in the BMI Associated with Lowest Risk of Death
JAMA - Journal of the American Medical Association

In a study appearing in the May 10 issue of JAMA, Børge G. Nordestgaard, M.D., D.M.Sc., of Copenhagen University Hospital, Herlev, Denmark and colleagues examined whether the body mass index (BMI) value that is associated with the lowest all-cause mortality has increased in the general population over a period of 3 decades.

6-May-2016 11:05 AM EDT
Breast Cancer Screening Accuracy and Time Spent Evaluating Mammograms
JAMA - Journal of the American Medical Association

Longer time spent by film readers interpreting screening mammograms did not result in a reduced rate of breast cancer detection, according to a study appearing in the May 10 issue of JAMA.

6-May-2016 11:05 AM EDT
Study Examines Use of Telemedicine Among Rural Medicare Beneficiaries
JAMA - Journal of the American Medical Association

Although the number of Medicare telemedicine visits increased more than 25 percent a year for the past decade, in 2013, less than 1 percent of rural Medicare beneficiaries received a telemedicine visit, according to a study appearing in the May 10 issue of JAMA.

6-May-2016 11:05 AM EDT
Drug Does Not Reduce Digital Ulcers in Patients with Systemic Sclerosis
JAMA - Journal of the American Medical Association

In an article appearing in the May 10 issue of JAMA, Dinesh Khanna, M.D., of the University of Michigan Scleroderma Program, Ann Arbor, and colleagues evaluated the efficacy of the drug macitentan in reducing the number of new digital ulcers in patients with systemic sclerosis.

22-Apr-2016 7:05 PM EDT
Time Spent Working Rotating Night Shift and Risk of Heart Disease
JAMA - Journal of the American Medical Association

Among female registered nurses, working a rotating night shift for 5 years or more was associated with a small increase in the risk of coronary heart disease, according to a study appearing in the April 26 issue of JAMA.

22-Apr-2016 7:05 PM EDT
Outcomes of Immunotherapy Tablet for House Dust Mite Allergy-related Asthma
JAMA - Journal of the American Medical Association

The addition of a house dust mite (HDM) sublingual allergen immunotherapy (SLIT) tablet to maintenance medications improved time to first moderate or severe asthma exacerbation during a period of inhaled corticosteroid (ICS) reduction among adults with HDM allergy-related asthma not well controlled by ICS, according to a study appearing in the April 26 issue of JAMA.

22-Apr-2016 7:05 PM EDT
Breast Density and Outcomes of Supplemental Breast Cancer Screening
JAMA - Journal of the American Medical Association

In a study appearing in the April 26 issue of JAMA, Elizabeth A. Rafferty, M.D., formerly of Massachusetts General Hospital, Boston, and colleagues evaluated the screening performance of digital mammography combined with tomosynthesis (a type of imaging) compared with digital mammography alone for women with varying levels of breast density.

22-Apr-2016 7:05 PM EDT
Poor Understandability of Notifications Sent to Women Regarding Breast Density
JAMA - Journal of the American Medical Association

In a study appearing in the April 26 issue of JAMA, Nancy R. Kressin, Ph.D., of the Veterans Affairs Boston Healthcare System, Boston University School of Medicine, and colleagues examined the content, readability, and understandability of dense breast notifications sent to women following screening mammography.

8-Apr-2016 4:05 PM EDT
Decrease in Air Pollution Associated With Decrease in Respiratory Symptoms Among Children
JAMA - Journal of the American Medical Association

Decreases in ambient air pollution levels over the past 20 years in Southern California were associated with significant reductions in bronchitic symptoms in children with and without asthma, according to a study appearing in the April 12 issue of JAMA.



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