By utilizing the power of electronic medical records, researchers from UC San Diego are uncovering the genetics of tobacco use, which would help scientists discover new ways to stop occasional tobacco use from evolving into tobacco use disorder.
A group of researchers based at UC San Diego and Rady Children's Institute have advanced the understanding of how the cerebral cortex develops by tracing the lineage of certain brain cells.
Researchers from UC San Diego have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.
Researchers at the University of California San Diego School of Global Policy and Strategy have developed a new method to predict the financial impacts climate change will have on agriculture, which can help support food security and financial stability for countries increasingly prone to climate catastrophes.
Some people have genes that protect them from alcohol abuse. An examination of databases at 23andMe reveal that those same alcohol-protective variants have associations with conditions and behaviors that may have nothing to do with alcohol.
Owning a home has long been considered a crucial way to build wealth, but making such a purchase has become increasingly difficult for many residents. In addition to steep housing prices and high interest rates, there have been a growing number of all-cash buyers who can close a deal quickly, beating out competing offers from buyers who need to finance their home with a mortgage.
Researchers at UC San Diego have received new grants that will help develop full-body imaging techniques to detect inflammation, which is currently very difficult to visualize in the clinic.
Using cutting-edge computational methods and supercomputing infrastructure at UC San Diego, researchers have built the largest and most detailed bird family tree to date—an intricate chart delineating 93 million years of evolutionary relationships between 363 bird species, representing 92% of all bird families.
UC San Diego biologists have uncovered a quality control timing mechanism tied to cell division. The “stopwatch” function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology’s edits are still imperfect. Researchers have developed a new system to test and analyze CRISPR-based DNA repair and related risks from unintended but harmful “bystander” edits.
Despite broad progress toward achieving equity in the workplace and educational achievement, data shows women still ascend the corporate ladder slower than their male peers and lag behind men in salary earnings.
Finding viable alternatives to traditional petroleum-based plastics and microplastics has never been more important. New research from scientists at UC San Diego and Algenesis shows that their plant-based polymers biodegrade — even at the microplastic level — in under seven months.
The stress-induced mechanisms that cause our brain to produce feelings of fear in the absence of threats — such as in PTSD — have been mostly a mystery. Now, neurobiologists have identified the changes in brain biochemistry and mapped the neural circuitry that cause generalized fear experiences.
To advance neuromorphic computing, some researchers are looking at analog improvements--advancing not just software, but hardware too. Research from the UC San Diego and UC Riverside shows a promising new way to store and transmit information using disordered superconducting loops.
UC San Diego Professor of Physics Nigel Goldenfeld has shown in theoretical models of turbulence that even molecular motions can create large-scale patterns of randomness over a defined period of time.
Researchers found that a formula used in statistical analysis provides a streamlined mathematical description of how neural networks, such as GPT-2, a precursor to ChatGPT, learn relevant patterns in data, known as features. This formula also explains how neural networks use these relevant patterns to make predictions. The team presented their findings in the March 7 issue of the journal Science.
Researchers from Skaggs School of Pharmacy and Pharmaceutical Science at the University of California San Diego have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.
A new study of migrant drowning deaths in the Pacific Ocean lays the groundwork for future research.
Greg Rouse, a marine biologist at UC San Diego’s Scripps Institution of Oceanography, and other researchers have discovered a new species of deep-sea worm living near a methane seep some 50 kilometers (30 miles) off the Pacific coast of Costa Rica. Rouse, curator of the Scripps Benthic Invertebrate Collection, co-authored a study describing the new species in the journal PLOS ONE that was published on March 6.
An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journals of the American College of Cardiology: Basic to Translational Science. The study, by a research team from the University of California San Diego, Georgia Institute of Technology and Emory University, was conducted in rodents.
UC San Diego engineers developed a cathode material for lithium-sulfur (Li-S) batteries that is healable and highly conductive, overcoming longstanding challenges of traditional sulfur cathodes. The advance holds promise for bringing more energy dense and low-cost Li-S batteries closer to market.
Unlike existing work, which relies on training data from social media examples, a new benchmark, named ToxicChat, is based on examples gathered from real-world interactions between users and an AI-powered chatbot. ToxicChat is able to weed out queries that use seemingly harmless language but are actually harmful, which would pass muster with most current models.
New research published in the Proceedings of the National Academy of Sciences (PNAS) shows that models commonly used to shape climate mitigation need to include human behaviors and rules—and shows models can be adapted to do so
According to new research from UC San Diego, sitting for long hours without breaks increases risk of death.
Individuals with Williams syndrome have a gregarious “cocktail party” personality, while those with the opposite genetic alteration, in contrast, tend to have autistic traits and are prone to struggle socially. Research from UC San Diego sheds new light on the gene responsible.
Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.
New research from the UC San Diego Rady School of Management and Texas A&M University finds that having self-control is often what leads to power.
To become carbon neutral by 2060, as mandated by President Xi Jinping, China will have to build eight to 10 times more wind and solar power installations than currently exist in the country. Reaching carbon neutrality will also require major construction of transmission lines.
Study shows greater muscle area in men leads increased risk of heart disease; it’s different for muscle density.
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Scientists at the University of California San Diego and CEA-Leti have developed a ground-breaking piezoelectric-based DC-DC converter that unifies all power switches onto a single chip to increase power density. This new power topology, which extends beyond existing topologies, blends the advantages of piezoelectric converters with capacitive-based DC-DC converters.
White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens.
Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.
Scientists hope to advance precision medicine through the discovery of a gene variant that leads to the same phenotype in separate high-dwelling populations while taking a different evolutionary path.
The University of California San Diego and Point Loma Nazarene University will co-host the 23rd annual Kyoto Prize Symposium on March 13 and 14.
Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts.
Researchers from University of California San Diego have developed a new search tool to that can match microbes to the metabolites they produce with no prior knowledge, an innovation that could transform our understanding of both human health and the environment.
UC San Diego engineers have developed an ultra-sensitive sensor made with graphene that can detect extraordinarily low concentrations of lead ions in water.
Computer scientists found that email notifications to update passwords potentially yielded diminishing returns after three messages.
A new system that brings together real-world sensing and virtual reality would make it easier for building maintenance personnel to identify and fix issues in commercial buildings that are in operation.
UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain.
Cancer resists treatment in a multitude of ways, but a new algorithm developed by scientists at UC San Diego can decode them all simultaneously.
Sensors built with a new manufacturing approach are capable of recording activity deep within the brain from large populations of individual neurons--with a resolution of as few as one or two neurons--in humans as well as a range of animal models, according to a study published in the Jan. 17, 2024 issue of the journal Nature Communications.
A vaccine for Staphylococcus aureus, one of the most common bacterial infections, would be a game changer for public health. No vaccine candidates have succeeded in clinical trials, but nobody knows why. Researchers at UC San Diego may have figured it out.
The effects of aging and external factors like UV exposure on skin are well documented. As people age or spend more time in the sun, their skin tends to become drier and more wrinkled. Recent findings have identified an exciting potential new link to signs of skin aging—the skin microbiome, the collection of microorganisms that inhabits our skin.
Researchers at the University of California San Diego have developed a neural implant that provides information about activity deep inside the brain while sitting on its surface.
Researchers from UC San Diego have developed a noninvasive approach for predicting the quality of lab-fertilized embryos using leftover culture medium.
A team led by UC San Diego Professor of Astronomy and Astrophysics Alison Coil believes they may have found the origin of the universe's giant odd radio circles: they are shells formed by outflowing galactic winds, possibly from massive exploding stars known as supernovae.
UC San Diego has received a $5 million grant from the Agency for Healthcare Research and Quality (AHRQ) to establish a Center for Learning Health Systems Science.
Following years of research and the power of a technologically advanced instrument, UC San Diego scientists have detailed the complex nanoscale exoskeleton patterns of the roundworm, a model laboratory organism, revealing clues about how skin layers are bound together.
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