A novel approach to gene therapy is improving lives in ways once thought impossible. Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a new platform to deliver the gene therapy precisely to specific areas of the brain.
A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status.
Treating anxiety and depression significantly reduced emergency room visits and rehospitalizations among people with heart disease, according to a study by researchers at The Ohio State University Wexner Medical Center.
Exercising during pregnancy doesn’t just benefit moms – it may also give their babies a head start on their heart health after birth, according to a study by researchers at The Ohio State University Wexner Medical Center.
Women are more likely than men to get diagnosed with multiple sclerosis (MS), an incurable disease that affects the central nervous system.
Physician scientists at The Ohio State University Wexner Medical Center and College of Medicine are studying why multiple sclerosis (MS) worsens as patients grow older. The "Aging with MS Clinic" provides complete care for older adults with MS.
The Robert F. Wolfe and Edgar T. Wolfe Foundation has made a $50 million commitment to The Ohio State University Wexner Medical Center’s new hospital tower, set to open in 2026. This is among the largest gifts ever made to the medical center.
Post traumatic stress disorder (PTSD) is common among U.S. military veterans. It’s also linked with higher risk of suicidal thoughts and behaviors.
Heart disease is the No. 1 cause of death for men and women in the United States. Eating a healthy diet and exercising help keep the heart healthy along with regular checkups with a doctor.
For decades, the number on a scale has been a key factor in deciding whether a person is healthy or not. But weight alone doesn’t paint a complete picture of one’s health.
Today, The Ohio State University and Ohio Governor Mike DeWine announced a new research initiative to identify the root causes of the ongoing epidemic of persistent emotional distress, suicide, and drug overdose in the state of Ohio.
Nationwide Children’s Hospital and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute celebrated the opening of a $100 million, 55,000 square foot proton therapy center, the first treatment facility in central Ohio offering this highly targeted form of radiation therapy for treatment of complex tumors that cannot be removed through surgery.
Acute spinal cord injury (SCI) patients lose body weight and muscle mass, despite being on a high-calorie diet while in the intensive care unit. Their muscle wasting is substantial and extends beyond what can explained by inactivity or denervation (loss of nerve supply) alone.
The National Academy of Inventors (NAI) has elected two Ohio State University College of Medicine professors to its 2023 class of Fellows. Krystof Bankiewicz, MD, PhD in the Department of Neurological Surgery, and Michael Tweedle, PhD, professor emeritus in the Department of Radiology, are among the 162 academic inventors named NAI Fellows this year.
The holiday season is a time for joy and celebration but many Americans admit the endless flurry of activities make it difficult to eat healthy, exercise and get adequate rest, according to a new survey from The Ohio State University Wexner Medical Center.
In a study led by a team at The Ohio State University Wexner Medical Center and Ohio State’s Wexner Center for the Arts, patients suffering from digestive symptoms were prescribed participation in an art program designed to help ease stress associated with their chronic illness.
A research team at The Ohio State University Wexner Medical Center and College of Medicine has been approved for a $14 million award from the Patient-Centered Outcomes Research Institute (PCORI) to study whether a higher daily dose of aspirin is more effective in decreasing the risk of dangerous blood pressure complications among some pregnant people.
The season of comfort and joy is upon us, but a new survey finds that for many Americans, it’s the season of stress and worry. The survey commissioned by The Ohio State University Wexner Medical Center and College of Medicine finds Americans are feeling the strain from inflation and world affairs.
Despite the Centers for Disease Control and Prevention warning this year will be potentially dangerous for respiratory illnesses, a third of Americans are not concerned about the threat, according to a new national survey by The Ohio State University Wexner Medical Center.
A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia and Non-Hodgkin lymphoma whose disease has stopped responding to standard treatments.
A new study from The Ohio State University Wexner Medical Center, University of Utah and University of Exeter (UK) substantiates previous groundbreaking research that rumination (overthinking) can be reduced through an intervention called Rumination-focused Cognitive Behavioral Therapy (RF-CBT).
Two five-year grants totaling more than $6 million from the National Cancer Institute will help The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute researchers and colleagues at other institutions better understand acute myeloid leukemia genetics and the role of inflammation in regulating immune response to this disease.
A $3.6 million award from the National Institutes of Health will allow neurosurgical, neurology and neuroscience researchers at The Ohio State University Wexner Medical Center and College of Medicine to test a novel diagnosis and treatment combination for painful diabetic neuropathy.
Researchers at The Ohio State University Wexner Medical Center and led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
Research led by The Ohio State University Wexner Medical Center and Wesleyan University found that depression screening tools outperformed suicide risk screenings under most conditions.
The Ohio State University Wexner Medical Center is one of the first nationwide to administer a targeted gene therapy for patients with a specific form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.
Gene therapy might offer a one-time, sustained treatment for patients with serious alcohol addiction, also called alcohol use disorder, according to a new study led by a researcher at The Ohio State University Wexner Medical Center and College of Medicine.
Gestational diabetes is on the rise among pregnant people, and now Ohio State University Wexner Medical Center has received a $12 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) to define the best treatment. The study will compare oral metformin versus injectable insulin.
Researchers continue to refine and improve targeted drug therapies that have changed the most common form of adult leukemia – from an incurable to a chronic condition. New data published in the New England Journal of Medicine offers another treatment option for patients who have stopped responding to the first and second generation drugs.
Interventional radiologists at Ohio State Wexner Medical Center are offering a minimally invasive procedure to give women a simpler option to relieve uterine fibroid symptoms without having to undergo a hysterectomy. Together with physicians in obstetrics and gynecology, the interventional radiology team can help patients by performing uterine fibroid embolization, which preserves the uterus.
Suicide rates have been increasing for decades, along with a national shortage of mental health professionals. The Suicide and Trauma Reduction Initiative for Veterans (STRIVE) at The Ohio State University Wexner Medical Center is designed to meet this growing need.
Leveraging the HEALing Communities Study infrastructure, researchers are testing whether there is an association between fentanyl test strip use and overdose risk reduction behaviors among people who use drugs over a 28-day observation period. The Stay Safe Study will be in Kentucky, Ohio and New York.
A new device invented with the help of an electrophysiologist at The Ohio State University Wexner Medical Center makes a heart procedure safer for patients suffering from atrial fibrillation (AFib), a common irregular heart rhythm.
New smart-drug treatment options for pancreatic cancer, immuno-oncology treatments and real-time immune-monitoring strategies are among the research topics to be presented by investigators at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) at the American Association for Cancer Research (AACR) annual meeting held April 14-19 at the Orange County Convention Center in Orlando, Florida.
James P. Allison, PhD, is the recipient of the 25th Herbert and Maxine Block Memorial Lectureship Award for Distinguished Achievement in Cancer. A 2018 Nobel Prize co-recipient in physiology/medicine, Allison serves as the chair of immunology and executive director of the Immunotherapy Platform at The University of Texas MD Anderson Cancer Center.
There is new evidence that fibromyalgia, and the chronic pain associated with it, could worsen opioid use disorder. Researchers at The Ohio State University Wexner Medical Center, College of Medicine and University of Michigan report their findings in the journal PAIN.
An ongoing longitudinal study of 1,400 patients by researchers at The Ohio State University Wexner Medical Center and College of Medicine reveals that traumatic brain injuries don’t stabilize after a couple of years as previously thought.
Implementation of a state-level insurance policy that prohibits discrimination based on gender identity or gender expression can increase access to gender-affirming surgical care, according to a new study by The Ohio State University Wexner Medical Center and College of Medicine.
In an effort to improve clinical trial diversity, researchers at The Ohio State University Wexner Medical Center and College of Medicine led a study to create solutions to barriers of access, awareness, discrimination and racism and workforce diversity.
The increasing frequency of active shooter incidents and other mass casualty events places heighten pressure on first responders to quickly assess, triage and treat victims to save lives. To help first responders prepare for these critical events, The Ohio State University College of Medicine developed a cutting-edge virtual reality disaster response training program.
While computed tomography (CT) scans can provide important information to diagnose illnesses and conditions, these imaging tests can also reveal other unrelated issues, known as “incidental” findings, that raise questions beyond what the physicians were originally looking for. The new Lung Nodule Program at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) combines the benefits of automated natural language processing tools with a subspecialized treatment team to create a system for flagging and methodically evaluating incidental lung nodule findings to capture subtle signs of lung cancer. Experts estimate this program could result in hundreds of lives saved annually through early detection.
A mouse study by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, provides new ways to determine how maternal and paternal exercise improve metabolic health of offspring.
COLUMBUS, Ohio – The first year of the COVID-19 pandemic saw a 113% increase in the “Years of Life Lost” among adolescents and young people in the United States due to unintentional drug overdose, according to researchers at The Ohio State University Wexner Medical Center and College of Medicine.
New study data shows that the immuno-oncology drug, atezolizumab is a safe and effective treatment for stage IB-IIIB non-small cell lung cancer patients prior to lung cancer surgery, according to a new study led by researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute as part of the national Lung Cancer Mutation Consortium 3 study. Researchers found that the survival of patients in this new study was far better – about 80% at three years post treatment and approximately twice as good as that which would be expected with surgery and chemotherapy alone. Study investigators also report data showing that the presence of high numbers of natural killer (NK) cells – a type of immune cell found in the blood before treatment – were associated with poor immunotherapy treatment effectiveness in this study. Patients with high levels of these cells might benefit from the addition of NK-specific therapy.
An unexplained case of severe coronary artery disease in a seemingly healthy young man led scientists at The Ohio State University Wexner Medical Center and College of Medicine to a discovery that could lead to a new way to treat high cholesterol.
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