Why we lose fat and muscle during infection
Salk Institute for Biological StudiesAlthough infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.
Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.
Brains are like puzzles, requiring many nested and codependent pieces to function well.
Young children sometimes believe that the moon is following them, or that they can reach out and touch it.
Obesity and metabolic diseases, such as diabetes, are extremely common in the United States.
Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.
Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself.
Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.
Partnership of government, academics and industry will develop new ways of studying and screening drugs for major psychiatric illnesses.
Salk Institute ranks as one of the leading scientific “stars” in North America with high-quality output that has grown particularly fast, according to a new report by Nature Research.
The Salk Institute is pleased to announce the appointment of Sung Han as an assistant professor in the Clayton Foundation Peptide Biology Laboratories. Han will study small molecules, called neuropeptides, which affect the brain’s defense response and contribute to sensory hypersensitivity in neuropsychiatric disorders such as anxiety and autism.
Salk team first to discover protein that controls the strength of body’s circadian rhythms
The Salk Institute awarded two American scientists with its prestigious Medal for Research Excellence, a distinction that has only been bestowed twice before in the Institute’s 55-year history. The honorees, who received their awards April 13, independently addressed the Salk community in presentations prior to an awards reception.
By adolescence, your brain already contains most of the neurons that you'll have for the rest of your life. But a few regions continue to grow new nerve cells--and require the services of cellular sentinels, specialized immune cells that keep the brain safe by getting rid of dead or dysfunctional cells.
The discovery has implications for understanding how the human brain evolved and how it varies between people
Data from the Salk Institute shows brain’s memory capacity is in the petabyte range, as much as entire Web.
Salk Cancer Center appoints Reuben Shaw as new director.
Renowned molecular biologist and scientific leader to join Salk January 1, 2016
Researchers identify a new core element of primate jumping genes capable of producing previously unknown proteins
The new technique allows scientists to study diseases like Alzheimer’s and Parkinson’s using cells from human patients
Salk researchers find correlation between declining ability to smell and lifespan in worms
New technique to selectively and noninvasively turn on groups of neurons in worms could be boon to science and medicine
Salk scientists find key molecular mechanism that underlies deadly behavior in hard-to-treat breast cancer
The new approach shows how cells in the spinal cord synchronize many neurons at once to allow complex movements, which could have implications for treating spinal cord injuries and diseases
Salk researchers show how DNA repair proteins sound the alarm to threats, pointing to a novel cancer therapy
Mice lacking a set of receptors in one type of neuron in the brain developed compulsive, anti-social behaviors, Salk scientists found
Salk scientists unveil how a critical molecule turns on T cells.
Salk and Carnegie Mellon researchers uncover how the brain prunes back synapses in development
Salk scientists have created mutation-free lines of stem cells from human patients with mitochondrial diseases.
Salk Institute research team aims to discover the fundamental causes of disease to generate successful treatments.
Researchers have developed antibodies to help study critical chemical modifications responsible for a protein’s development
Salk scientists find that dietary fat, coupled with a natural hormone, can relieve metabolic dysfunction associated with mitochondrial disease in mice
The Salk Institute and Sanford Burnham Prebys Medical Discovery Institute created a compound that stops a cellular recycling process
A protein long believed to only guard the nucleus also regulates gene expression and stem cell development
Salk scientists find a single molecule that controls the fate of mature sensory neurons
Salk Institute scientists discover new type of stem cell that could potentially generate mature, functional tissues
Salk scientists’ finding could aid regenerative and cancer therapies
Salk scientists use molecular “scissors” to eliminate mitochondrial mutations in eggs and embryos
Salk scientists discover a learning circuit in worms that gives clues to human behavior.
Salk scientists discover a single protein that energizes muscles and the brain
Salk researchers have been able to grow patient-derived, healthy cells in the lab, coming a step closer to treating fatal blood disorders
Salk scientists re-engineered the bacterial defense system CRISPR to recognize HIV inside human cells and destroy the virus, offering a potential new therapy.
Salk scientists discover how a "mini-brain" in the spinal cord aids in balance
Salk scientists made a more effective diet pill
Salk scientists develop a theory to explain how animals gather information and switch attention
Findings could lead to new therapeutics for disorders such as fibromyalgia and phantom limb pain.
Salk researchers tinker with a time-restricted diet in mice and find that it is remarkably forgiving.
The new method lets researchers identify weak and previously undetectable interactions between proteins inside living cells
A combination of two unexpected drugs targets tumors
Researchers regenerate and heal mouse hearts by using the molecular machinery the animals had all along.
Salk scientists have made several key discoveries related to the disease