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Pediatrics, Pediatric Oncology, Immunotherapy, CAR T cells, All, Acute Lymphoblastic Leukemia

In Clinical Trials, CAR T Cell Immunotherapy Continues to Yield Complete Responses in Children & Young Adults with Relapsed and Refractory Leukemia

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A highly innovative, personalized cell-based treatment for a high-risk form of the most common childhood cancer continues to move through clinical trials. Pediatric oncologists from Children’s Hospital of Philadelphia (CHOP) today reported new results using T cell immunotherapy against relapsed or refractory acute lymphoblastic leukemia (ALL).

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Leukemia, MDs, AML, AZA, MD Anderson Cancer Center

Research Shows Patients Ineligible for Studies May Benefit From Trial Participation

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Patients who potentially could benefit most from participation in clinical trials due to poor prognoses often are not included based on eligibility criteria, such as existing medical illnesses.

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Hematology, Oncology, Pediatrics, aplastic anemia, Bone Marrow Transplant

Rainbow Babies & Children’s Experts to Present Pediatric Focused Data at 58th American Society of Hematology Annual Meeting

Ashish Gupta, MBBS, MPH, a pediatric hematology fellow, will share results from one of the largest quality controlled retrospective studies of children with acquired aplastic anemia. The data makes a compelling case for the pediatric hematology community to revisit the current treatment algorithm for this rare disease.

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CBD oil, Epilelpsy, Seizures, Epidiolex, cannabidiol

CBD Oil May Reduce Frequency and Severity of Epileptic Seizures, According to UAB Findings

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Cannabidiol oil, also known as CBD oil, reduces the frequency and severity of seizures in children and adults with severe, intractable epilepsy, according to findings presented by researchers from UAB at the American Epilepsy Society 70th Annual Meeting.

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Case Western Reserve University, case school of engineering, Case Western Reserve School of Medicine

Filling Need for Fast and Accurate Assessment of Blood’s Ability to Clot

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Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person’s blood 95 times faster than current methods—using only a single drop of blood.

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A Bacterial Aphrodisiac, Amyloids Protecting Dormant Eggs and Zika’s Cellular Damage Among Top Honor Cell Biology Picks at ASCB 201

ASCB names 10 "Novel & Newsworthy" Honor abstracts out of 1263 being presented in San Francisco, Dec. 3-7

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Cancer, immunotheraphy, CAR T cell, Chronic Lymphocytic Leukemia, Cameron Turtle, David Maloney, Stan Riddell

CD19-Targeting CAR T-Cell Immunotherapy Yields High Responses in Treatment-Resistant CLL

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In a small, early phase trial, a high percentage of patients who had exhausted most traditional treatments for chronic lymphocytic leukemia saw their tumors shrink or even disappear after an infusion of a highly targeted, experimental CAR T-cell immunotherapy developed at Seattle’s Fred Hutchinson Cancer Research Center.

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Hemophilia, Gene Therapy, Hemophilia B, Clinical Trial, clotting factor IX, Children's Hospital Of Philadelphia

After One Dose of Gene Therapy, Hemophilia B Patients Maintain Near-Normal Levels of Clotting Factor

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Researchers are reporting the highest and most sustained levels to date of an essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B. After receiving a single dose of an experimental gene therapy in a clinical trial, patients with hemophilia produced near-normal levels of clotting factor IX, allowing them to stop clotting factor infusions and to pursue normal activities of daily life without disabling bleeding episodes.

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Acute Myeloid Leukemia

CPX-351 Improves Survival Following Allogeneic Hematopoietic Cell Transplant in Older High-Risk Acute Myeloid Leukemia Patients, Says Moffitt Cancer Center Physician

Analysis of a phase 3 trial shows that older patients with high-risk or secondary AML, who received initial treatment with CPX-351, had improved survival following allogeneic hematopoietic cell transplant, when compared with patients who received standard 7+3 cytarabine and daunorubicin as initial therapy.

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myelodysplastic syndromes (MDS)

Moffitt Cancer Center Study Shows Improved Response Rates in Myelodysplastic Syndromes Patients Treated with Lenalidomide and Epoetin Alpha

Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia. Many patients with lower-risk MDS benefit from treatment with recombinant-erythropoietin (rHuEPO), which stimulates blood cell production.

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ASH Conference, Hematologic Cancers, Blood Cancers, Lymphoma, Leukemia, Myeloma

City of Hope Experts Can Discuss ASH Studies on Blood Cancers

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Stem Cells, Cells, Ips Cells

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 5-Dec-2016 3:00 PM EST

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Knee Replacement, partial knee replacement, unicompartmental knee replacement, Hospital For Special Surgery

Partial Knee Replacement Enables World Traveler to Resume Active Lifestyle

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World travel is an important part of David's job, but knee pain was slowing him down. After consulting with a number of doctors, he decided to travel to Hospital for Special Surgery in New York City, where he learned he was a candidate for a partial joint replacement.

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Gay Men, College of Global Public Health, NYU, New York University, Gay Minorities, Cortisol

NYU Researchers Identify Stress-Hormone Differences Among Gay Men

Increased stigma and discrimination can affect circadian HPA-axis functioning; the majority of previous studies have been conducted among white heterosexuals, with very little research examining HPA-axis functioning between different minorities. Individuals who identify as both sexual and racial minorities may experience increased stigma and discrimination that can affect this HPA-axis functioning. NYU researchers examined differences in diurnal cortisol rhythm between young, self-identified, white gay men and black gay men.

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science writer job, medical writer job, writer wanted, Employment, Los Angeles writing job

Seeking Full-Time Editor/Writer

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USC Keck Medicine in Los Angeles seeks a full-time Editor/Writer in its PR & Marketing office to perform general media relations duties with an emphasis on writing and editing press releases.

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Inflammation, Uv Light, Inflammatory Disease

New Tool Uses UV Light to Control Inflammation

Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light.

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Evaluation of Scientific Rigor in Animal Research

The “reproducibility crisis” in biomedical research has led to questions about the scientific rigor in animal research, and thus the ethical justification of animal experiments. In research publishing in the Open Access journals PLOS Biology and PLOS ONE on December 2nd, 2016, researchers from the University of Bern have assessed scientific rigor in animal experimentation in Switzerland. The study, commissioned by the Swiss Federal Food Safety and Veterinary Office (FSVO), found widespread deficiencies in the reporting of experimental methodology.

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genetics and autism

Landmark Autism Genetic Study Seeking Participants

Families with a loved one on the autism spectrum now have an opportunity to participate in a landmark study researching the genetics of autism. The national study is the largest autism research project to date.

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Immunotherapy, Cancer, CAR-T, American Society Of Hematology

Penn Medicine and Children's Hospital of Philadelphia Researchers to Present Findings of Personalized Cellular Therapies

Researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP) will present the latest advances from their studies of personalized cellular therapies for blood cancers during the 58th Annual Meeting of the American Society of Hematology (ASH) in San Diego.

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Abuse, Hospital, Operating Room, Staff, Behavior

Abusive Behavior in the Operating Room?

A new study has found that healthcare workers in operating rooms are at a risk of witnessing physical and psychological abuse.







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