NIBIB-funded researchers have developed an interlinked tissue chip system that can model four mature organs in their perspective environments simultaneously. These multi-organ tissue chips could represent a new way to evaluate diseases or drugs that affect multiple different tissues.
The National Institutes of Health, through its Blueprint MedTech program, has established two incubator hubs and launched a funding solicitation in support of commercially viable, clinically focused neurotechnology solutions to diagnose and treat disorders of the nervous system.
A research team funded by the National Institutes of Health has shown that commercially available rapid antigen tests can detect past and present variants of concern and has identified potential mutations that may impact test performance in the future.
The NIH announces the winners of the DEBUT Challenge with prizes totaling $130,000
Two biomedical imaging technologies developed with support from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have been cleared for clinical use by the Food and Drug Administration (FDA). Both technologies offer advances in computed tomography (CT).
The National Institutes of Health announced the winners of its NIH Technology Accelerator Challenge (NTAC) for Maternal Health, a prize competition for developers of diagnostic technologies to help improve maternal health around the world.
Minority patient groups may receive less supplemental oxygen in the ICU due to inaccurate readings from pulse oximeters.
An interdisciplinary research team has developed a fast, cost-effective method to detect the circulation of SARS-CoV-2 variants. The approach can augment current surveillance methods that use comprehensive next-generation sequencing of virus samples, helping focus sequencing efforts on samples representing unknown and emerging variants.
Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide. To combat this issue, NIBIB-funded researchers are developing an implantable, biodegradable film that helps to regenerate the native cartilage at the site of damage. Their study, performed in rabbits, could be an initial, important step in the establishment of a new treatment for this common condition.
NIBIB-funded researchers are developing an imaging method that would allow surgeons to better identify cancerous cells in breast tumor margins during surgery. This technique could lead to a reduction in follow-up breast cancer surgeries and reduce rates of breast cancer recurrence.
NIBIB-funded researchers are developing an autonomous robot that can perform bowel surgery with minimal assistance from a surgeon. In preclinical models, the robot outperformed expert surgeons when compared head-to-head.
NIBIB-funded researchers are developing a method to activate natural killer cells using an external magnetic field, which not only enhances their cytotoxicity, but allows them to be tracked using magnetic resonance imaging (MRI) to verify that they’ve reached their target.
NIBIB-funded researchers are developing a robotic pill that, after swallowing, can deliver biologic drugs into the stomach, which could provide an alternative method for self-injection for a wide range of therapies.
NIBIB-funded researchers have found a way to model the human neuromuscular junction by growing these synapses in a lab, which could accelerate novel treatments for neuromuscular diseases.
NIH-funded researchers are investigating how to use smartwatches to predict clinical test results, which could potentially serve as an early warning signal for underlying health issues.
A team led by NIBIB scientists has developed hardware and software innovations to construct super-resolution, 3D confocal images of fine structures in living samples.
Fluorescent “dots”–that is, tiny particles that can emit light–have a multitude of promising biomedical applications, yet making such dots is usually a long, tedious process that uses harsh chemicals. Now, researchers are developing a fluorescent dot that is not only easier to make, but uses eco- friendly materials.
The NIH RADx initiative announced the launch of the When To Test Calculator for Individuals. By responding to just a few prompts, the new individual impact calculator indicates whether a person should get a test—now or soon.
NIBIB-funded engineers are using deep learning to differentiate tumor more accurately from normal tissue in positron emission tomography (PET).
The NIH RADx initiative announced today that it has issued contract awards totaling $77.7 million to develop and manufacture 12 new rapid diagnostic tests for SARS-CoV-2, the virus that causes COVID-19.
Bioengineers are using focused ultrasound to modulate motor activity in the brain without surgical device implantation, a first step toward non-invasive brain stimulation therapies.
NIBIB-funded researchers are working on an ankle prosthetic that relies on the user’s residual muscles—and the electrical signals that they generate—to help amputees control their posture continuously.
The gut microbiome can impact us in a variety of different ways, from our metabolism to our mood. Now, NIBIB-funded researchers are investigating if a fiber-based gel can restore beneficial microbes in the gut to enhance the efficacy of immune checkpoint inhibitors, a type of cancer immunotherapy treatment, in mice.
Placenta accreta spectrum (PAS) disorder occurs when the placenta remains attached to the uterus after childbirth. Now researchers have developed a blood test to identify this condition, enabling early intervention by high-risk pregnancy specialists.
NIBIB funding drives progress in the diagnosis, treatment, and monitoring of middle ear infections
Bioengineers have developed biocompatible self-assembling “piezoelectric wafers,” which can be made rapidly and inexpensively to enable broad use of implantable muscle-powered electromechanical therapies.
NIH-funded researchers at Carnegie Mellon University have demonstrated the potential of a neuromodulation approach that uses low-intensity ultrasound energy, called transcranial focused ultrasound—or tFUS.
Nanofiber-based treatments stimulate the body to mount its own biological attack on immune disorders.
In a study that compares rapid antigen and laboratory PCR approaches for COVID-19 serial screening, researchers affiliated with the NIH RADx initiative reported results from 43 people infected with the virus.
In a new study, NIH researchers report that the prevalence of COVID-19 in the United States during spring and summer of 2020 far exceeded the known number of cases and that infection affected the country unevenly.
A change of instructions in a computer program directs the computer to execute a different command. Similarly, synthetic biologists are learning the rules for how to direct the activities of human cells.
This study investigates how the nucleocapsid protein, or N protein, of the SARS-CoV-2 virus packages the viral genome.
A team of NIH microscopists and computer scientists used a type of artificial intelligence called a neural network to obtain clearer pictures of cells at work even with extremely low, cell-friendly light levels.
NIBIB-funded researchers are investigating long-lasting, customizable nanobubbles for ultrasound contrast agents.
The new technique is capable of printing organ models containing live cells in minutes instead of hours— a major step in the quest to create 3D-printed replacement organs.
One-year into implementation of the NIH RADx initiative, the IEEE Open Journal of Engineering in Medicine and Biology has dedicated a special issue to exploring the innovative structure and operation of the RADx Tech program.
The technique used in this preclinical study could aid tissue regeneration following severe accidents, surgical resections, or progressive muscle loss due to age or genetic disease.
The National Institutes of Health today announced three new contracts and one new award to an existing contract for scale-up and manufacturing of novel COVID-19 testing technologies. The four Rapid Acceleration of Diagnostics initiative contracts totals $65.6 million.
NIH has awarded four additional contracts for the development and scaled-up manufacturing of new COVID-19 diagnostic testing technologies through its Rapid Acceleration of Diagnostics Tech (RADx) initiative. The awards total $29.3 million and will help increase testing capacity for COVID-19.
CDC, in collaboration with the NIH, has launched a community health initiative called “Say Yes! COVID Test” starting in Pitt County, North Carolina, and coming soon to Chattanooga/Hamilton County Tennessee.
Abnormal heart rhythms—cardiac arrhythmias—are a major worldwide health problem. Now scientists are using ultrasound for more accurate maps of arrhythmic sites in the heart for improved success of ablation procedures.
The NIH RADx initiative awarded three new contracts totaling $36.7 million for the development of new COVID-19 diagnostic testing technologies and production of specimen collection kits and swabs.
Research into the gut-brain axis continues to reveal how the brain and gut influence each other’s health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.
The FDA granted emergency use authorization today for an innovative COVID-19 viral antigen test developed with support from NIH’s RADx Initiative.
Engineers have created 3D printed patient-specific models of the aorta that can aid presurgical planning and improve outcomes of minimally invasive valve replacement.
The COVID-19 Testing Impact Calculator is a free resource that shows how different approaches to testing and other mitigation measures, such as mask use, can curb the spread of the virus in any organization.
NIH, with BARDA, today announced a third round of contract awards for scale-up and manufacturing of new COVID-19 testing technologies.
NIH has awarded seven contracts to companies and academic institutions to develop digital health solutions that help address the COVID-19 pandemic.
NIH today announced $129.3 million in scale-up and manufacturing support for a new set of COVID-19 testing technologies as part of its RADx initiative. NIH is awarding contracts to nine companies for technologies that include portable point-of-care tests for immediate results and high-throughput laboratories that can return results within 24 hours.
The winners of National Institutes of Health’s 9th annual Design by Biomedical Undergraduate Teams (DEBUT) challenge developed simple and low-cost diagnostics and treatments for conditions such as tuberculosis, cervical cancer, birth defects, and onchocerciasis (river blindness).
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