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Released: 15-Dec-2016 2:05 PM EST
Does Good-Tasting Food Cause Weight Gain?
Monell Chemical Senses Center

Does eating good-tasting food make you gain weight? Despite the common perception that good-tasting food is unhealthy and causes obesity, new research from the Monell Center using a mouse model suggests that desirable taste in and of itself does not lead to weight gain.

Released: 1-Dec-2016 2:05 PM EST
Monell Center Receives Funding to Develop Technologies to Improve Taste of Lifesaving Drugs
Monell Chemical Senses Center

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

Released: 3-Oct-2016 1:15 PM EDT
Cold and Bubbly: The Sensory Qualities That Best Quench Thirst
Monell Chemical Senses Center

New research from the Monell Center finds that oral perceptions of coldness and carbonation help to reduce thirst. The findings could guide sensory approaches to increase fluid intake in populations at risk for dehydration, including the elderly, soldiers, and athletes.

Released: 1-Aug-2016 11:05 AM EDT
Monell Center Hosts First U.S. Smell-Training Workshop for Smell-Impaired and Recovering Anosmics
Monell Chemical Senses Center

The leading lay advocate for smell-training, will visit the Monell Center from the U.K. on August 9-11, 2016. During her visit she will present the first U.S. educational smell-training sessions for individuals with impaired smell and the physicians who treat them.

Released: 20-Jun-2016 12:05 PM EDT
Nancy E. Rawson Appointed Associate Director of Monell Center
Monell Chemical Senses Center

Nancy E. Rawson, PhD has been appointed Associate Director of the Monell Center, effective immediately. Rawson is a highly accomplished scientific leader with broad-based experience that spans academia and the food, flavor and nutritional products industries.

Released: 17-May-2016 4:15 PM EDT
New Partnership to Study Link Between Olfaction and Neurodegenerative Disease
Monell Chemical Senses Center

Deterioration in a person’s ability to smell can sometimes be an early sign of neurodegenerative diseases such as Parkinson’s or Alzheimer’s. Now, researchers at the Monell Center have established a collaboration with the Brain Health Registry to gain better insight into how changes in a person’s sense of smell may relate to health status and cognitive function.

5-May-2016 4:00 PM EDT
Digesting Sweet Taste: Gut Enzymes Localized in Taste Cells
Monell Chemical Senses Center

A new Monell study reports that sweet taste cells on the tongue also contain digestive enzymes capable of converting sucrose (table sugar) into glucose and fructose, simple sugars that can be detected by both known sweet taste sensing pathways. The findings increase understanding of the complex cellular mechanisms underlying sweet taste detection.

Released: 31-Mar-2016 10:05 AM EDT
Key Regulatory Role for Mysterious Olfaction Molecule OMP
Monell Chemical Senses Center

New research from the Monell Center reveals that olfactory marker protein (OMP), a molecule found in the cells that detect odor molecules, plays a key role in regulating the speed and transmission of odor information to the brain. The findings solve a 30-year-old mystery regarding the function of OMP.

Released: 29-Mar-2016 11:05 AM EDT
Danielle Reed Appointed Associate Director of Monell Center
Monell Chemical Senses Center

Danielle R. Reed, PhD, a world-recognized expert on the behavioral genetics of taste, has been named Associate Director of the Monell Center, effective immediately.

Released: 11-Feb-2016 12:05 PM EST
Unraveling the Enigma of Salty Taste Detection
Monell Chemical Senses Center

Scientists from the Monell Center have further characterized the identity and functionality of salt-responding taste cells on the tongue. The knowledge may lead to novel approaches to develop salt replacers or enhancers that can help reduce the sodium content of food while retaining desirable salty taste.

12-Jan-2016 12:45 PM EST
Odor Biomarker for Alzheimer's Disease
Monell Chemical Senses Center

A new study from the Monell Center, the U.S. Department of Agriculture, and collaborating institutions reports a uniquely identifiable odor signature from mouse models of Alzheimer’s disease. The findings suggest that it may be possible to develop a non-invasive tool for early Alzheimer’s diagnosis.

Released: 14-Dec-2015 11:05 AM EST
Children’s Ability to Detect Sugar Varies Widely
Monell Chemical Senses Center

According to new research from the Monell Center, sensitivity to sweet taste varies widely across school-aged children and is in part genetically-determined. The findings may inform efforts to reduce sugar consumption and improve nutritional health of children.

23-Nov-2015 12:10 PM EST
Low Sugar Diet Makes Foods Taste Sweeter But Does Not Change Preferred Level of Sweetness
Monell Chemical Senses Center

New research from the Monell Center reveals that while foods such as vanilla pudding taste sweeter following three months on a low-sugar diet, the level of sweetness most preferred in foods and beverages does not change. The findings may inform public health efforts to reduce the amount of added sugars that people consume in their diets.

9-Nov-2015 11:40 AM EST
Bitter Taste Sensitivity May Predict Surgical Outcome in Certain Chronic Rhinosinusitus Patients
Monell Chemical Senses Center

New research from the Monell Center and the Perelman School of Medicine at the University of Pennsylvania suggests that physicians may someday be able to use a simple taste test to predict which surgical intervention is best suited to help a subset of chronic rhinosinusitis patients.

15-Oct-2015 2:25 PM EDT
Meat-Eating Cats Retain Multiple Functional Bitter Taste Receptors
Monell Chemical Senses Center

Cats have at least seven functional bitter taste receptors, according to a new Monell Center study. Further, a comparison of cat to related species reveals little relationship between biter receptor number and the extent to which a species consumes plants. The findings question the common hypothesis that bitter taste developed primarily to protect animals from ingesting poisonous plant compounds.

16-Jul-2015 11:05 AM EDT
Some Like It Sweet, Others Not So Much: It’s Partly in the Genes
Monell Chemical Senses Center

A new study from the Monell Center and collaborating institutions suggests that a single set of genes accounts for approximately 30 percent of person-to-person variance in sweet taste perception, regardless of whether the sweetener is a natural sugar or a non-caloric sugar substitute.

Released: 7-May-2015 1:05 PM EDT
Monell Center and Drexel University Partner on Food and Flavor Science Program
Monell Chemical Senses Center

The Monell Center has established a formal partnership with Drexel University to promote education and research on flavor perception and food science. The agreement, which follows years of informal collaboration, leverages the respective strengths of two preeminent Philadelphia institutions.

16-Apr-2015 2:05 PM EDT
Immune System Protein Regulates Sensitivity to Bitter Taste
Monell Chemical Senses Center

New research from the Monell Center reveals that tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste. The finding may explain taste abnormalities and decreased food intake associated with infections, autoimmune disorders, and chronic inflammatory diseases.

Released: 20-Apr-2015 3:05 PM EDT
Two Monell Scientists Honored for Significant Achievements in Taste and Smell Research
Monell Chemical Senses Center

Two Monell Center scientists have been recognized by the Association for Chemoreception Sciences (AChemS) for their contributions to the understanding of the senses of taste and smell. Robert F. Margolskee, MD, PhD, the Center’s Director and President, and Joel Mainland, PhD, Louise Slade Assistant Member, will be honored at the upcoming 2015 AChemS Annual Meeting.

Released: 24-Feb-2015 12:25 PM EST
Monell Center Marks Anosmia Awareness Day with New Educational Materials on Smell Loss
Monell Chemical Senses Center

The Monell Center announces a CME Program, FAQ sheet and video to promote Anosmia Awareness Day on February 27. Each was designed to increase awareness and increase the limited information available on anosmia, the loss of our sense of smell, which affects many millions worldwide.

Released: 22-Jan-2015 1:35 PM EST
Monell Center Awarded Grant to Evaluate Role of Nasal Airflow Obstruction in Smell Loss
Monell Chemical Senses Center

The Monell Center has received a $1.5M NIH grant to further develop clinical methodology that can predict the path of air flow through a person’s nasal passages. The methodology may someday help physicians predict success taes for surgery to reverse nasal obstruction and associated loss of smell (anosmia).

Released: 27-Oct-2014 2:00 PM EDT
New Monell Center President Robert Margolskee Announces $1 Million in Leadership Challenge Gifts
Monell Chemical Senses Center

The Monell Chemical Senses Center announces $1 million in leadership challenge gifts from Board members Richard L. Berkman, Esq., and Dwight Riskey, PhD. The gifts, made in honor of Monell Director Emeritus Gary Beauchamp, PhD, will support new faculty recruitment in the areas of nutrition, taste, and olfaction.

Released: 18-Aug-2014 4:25 PM EDT
Monell Center Names Robert F. Margolskee as New President and Director
Monell Chemical Senses Center

The Board of Directors of the Monell Chemical Senses Center has named Robert F. Margolskee, MD, PhD as the Center’s next President and Director, effective October 1, 2014. Margolskee will be the Center’s third Director since its founding in 1968, succeeding Gary K. Beauchamp, PhD, who has led Monell since July 1990.

Released: 22-Jul-2014 3:00 PM EDT
In Asthma, It’s Not Just What You Smell, But What You Think You Smell
Monell Chemical Senses Center

New research from the Monell Center reveals that simply believing that an odor is potentially harmful can increase airway inflammation in asthmatics for at least 24 hours following exposure. The findings highlight the role that expectations can play in health-related outcomes.

Released: 3-Jun-2014 11:25 AM EDT
Stress Hormone Receptors Localized in Sweet Taste Cells
Monell Chemical Senses Center

A new study from the Monell Center reports that oral taste cells contain receptors for glucocorticoid “stress hormones”. The findings suggest glucocorticoids may act directly on taste cells to affect how they respond to sugars and other taste stimuli under conditions of stress.

Released: 29-May-2014 5:00 PM EDT
Pleasant Smells Increase Facial Attractiveness
Monell Chemical Senses Center

New research from the Monell Chemical Senses Center reveals that women’s faces are rated as more attractive in the presence of pleasant odors. In contrast, odor pleasantness had less effect on age evaluation. The findings suggest that perfumes and scented products may, to some extent, alter how people perceive one another.

Released: 2-Apr-2014 4:00 PM EDT
Body Odor Changes Following Vaccination
Monell Chemical Senses Center

New research from the Monell Chemical Senses Center and the U.S. Department of Agriculture (USDA) reveals that immunization can trigger a distinct change in body odor. This is the first demonstration of a bodily odor change due to immune activation.

21-Mar-2014 12:00 PM EDT
Bamboo-Loving Giant Pandas Also Have a Sweet Tooth
Monell Chemical Senses Center

Despite the popular conception of giant pandas as continually chomping on bamboo, new research from the Monell Center reveals that this highly endangered species also has a sweet tooth. Behavioral and molecular genetic studies demonstrate that the panda possesses functional sweet taste receptors and shows a strong preference for natural sweeteners.

12-Mar-2014 11:00 AM EDT
Children’s Preferences for Sweeter and Saltier Tastes Are Linked to Each Other and to Measures of Growth
Monell Chemical Senses Center

Scientists from the Monell Center have found that children who most prefer high levels of sweet tastes also most prefer high levels of salt taste and that, in general, children prefer sweeter and saltier tastes than do adults. These preferences also relate to measures of growth and can have important implications for efforts to change children’s diets.

Released: 27-Feb-2014 2:35 PM EST
A Sense of Hope: The Monell Anosmia Project
Monell Chemical Senses Center

On Anosmia Awareness Day, the Monell Center announces “A Sense of Hope: The Monell Anosmia Project,” a three-year $1.5M fundraising campaign to support a research and advocacy program focused on anosmia, the loss of the sense of smell.

Released: 12-Feb-2014 10:00 AM EST
Earwax: A New Frontier of Human Odor Information
Monell Chemical Senses Center

Scientists from the Monell Center have used analytical organic chemistry to identify the presence of odor-producing chemical compounds in human earwax. Further, the amounts of these compounds differ between individuals of East Asian origin and Caucasians. The findings suggest that human earwax could be an overlooked source of personal information.

22-Jan-2014 2:00 PM EST
Humans Can Use Smell to Detect Levels of Dietary Fat
Monell Chemical Senses Center

New research from the Monell Center reveals humans can use the sense of smell to detect and differentiate levels of dietary fat in everyday food.

5-Dec-2013 1:00 PM EST
Extensive Variability in Olfactory Receptors Influences Human Odor Perception
Monell Chemical Senses Center

Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.

11-Oct-2013 5:00 PM EDT
Avian Influenza Virus Detection Using Smell
Monell Chemical Senses Center

New research from the Monell Chemical Senses Center and the U.S. Department of Agriculture (USDA) reveals that avian influenza, which typically is asymptomatic, can be detected based on odor changes in infected birds. The results suggest a rapid and simple detection method to help prevent the spread of influenzas in avian populations.

5-Sep-2013 11:25 AM EDT
Variation in Bitter Receptor mRNA Expression Affects Taste Perception
Monell Chemical Senses Center

New findings from the Monell Center reveal that a person’s sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by how much messenger RNA -- the gene’s instruction guide that tells a taste cell to build a specific receptor – their cells make.

15-Aug-2013 10:00 AM EDT
Pop! Bursting the Bubble on Carbonation
Monell Chemical Senses Center

New research from the Monell Center reveals that bubbles are not necessary to experience the unique ‘bite’ of carbonated beverages, which actually comes from carbonic acid. Bubbles do, however, enhance carbonation’s bite through the light physical feel of the bubbles picked up by our sense of touch.

Released: 24-Jul-2013 12:25 PM EDT
Improving Medicine Acceptance in Kids: A Matter of Taste
Monell Chemical Senses Center

Bitterness presents a key obstacle to the acceptance and effectiveness of beneficial drugs by children worldwide. A new review addresses this critical problem by highlighting recent advances in the scientific understanding of bitter taste, with special attention to the sensory world of children.

Released: 17-Jul-2013 2:55 PM EDT
Monell Scientist Is Inaugural The Coca-Cola Company Postdoctoral Fellow in Taste Biology
Monell Chemical Senses Center

Yan Li, MD, PhD, has been named The Coca-Cola Company Postdoctoral Fellow in Taste Biology at the Monell Center. Dr. Li’s appointment will facilitate research designed to understand how humans taste sweetness.

26-Jun-2013 4:25 PM EDT
Inactivation of Taste Genes Causes Male Sterility
Monell Chemical Senses Center

Scientists from the Monell Center report the surprising finding that two proteins involved in oral taste detection also play a crucial role in sperm development. In addition, the human form of one protein is blocked by the lipid-lowering drug clofibrate, perhaps linking this and related compounds to the rising global incidence of human infertility.

Released: 13-Jun-2013 2:00 PM EDT
Research Identifies Scent of Melanoma
Monell Chemical Senses Center

Monell researchers identified odorants from human skin cells that can be used to identify melanoma, the deadliest form of skin cancer. In addition a nanotechnology-based sensor could reliably differentiate melanoma cells from normal skin cells. Non-invasive odor analysis may be a valuable technique in the detection and early diagnosis of human melanoma.

Released: 6-May-2013 1:00 PM EDT
Monell Scientists Identify Critical Link in Mammalian Odor Detection
Monell Chemical Senses Center

Researchers at the Monell Center have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally anosmic – unable to smell. The findings may lend insight into the underlying causes of certain smell disorders in humans.

Released: 25-Apr-2013 11:05 AM EDT
Monell Center Alum Dr. Larry Clark Named 2013 Kerry-Manheimer Awardee
Monell Chemical Senses Center

Larry Clark, PhD, Director of the United States Department of Agriculture National Wildlife Research Center (NWRC), is the 2013 recipient of the Monell Center’s Kerry-Manheimer Award.

Released: 15-Apr-2013 1:00 PM EDT
Peihua Jiang Receives Ajinomoto Award for Young Investigators in Gustation from AChemS
Monell Chemical Senses Center

Monell Center molecular neurobiologist Peihua Jiang, PhD, is the 2013 recipient of the Ajinomoto Award for Young Investigators in Gustation, an annual award presented by the Association for Chemoreception Sciences to a rising leader in the field of gustation.

4-Mar-2013 1:00 PM EST
Monell Scientists Help Identify a Missing Link in Taste Perception
Monell Chemical Senses Center

Working with a multidisciplinary consortium of 19 researchers from nine institutions, Monell scientists have provided critical information to identify CALHM1, a channel in the walls of taste receptor cells, as a necessary component in the process of sweet, bitter, and umami (savory) taste perception.

30-Jan-2013 10:25 AM EST
Monell Scientists Identify Elusive Taste Stem Cells
Monell Chemical Senses Center

Scientists at the Monell Center have identified the location and certain genetic characteristics of taste stem cells on the tongue. The findings will facilitate techniques to grow and manipulate new functional taste cells for both clinical and research purposes.

Released: 18-Dec-2012 11:55 AM EST
Louise Slade Gives $1 Million to Advance Research on Human Salty Taste at Monell Center
Monell Chemical Senses Center

The Monell Center announces a gift of $1million from food chemistry consultant Louise Slade, Ph.D. The funds will support Monell’s fundamental research program on the mechanisms of human salt detection and perception.

Released: 8-Oct-2012 1:50 PM EDT
Two Rising Leaders in Taste Science Join Monell Faculty
Monell Chemical Senses Center

The Monell Center announces the appointments of Ichiro Matsumoto, Ph.D., and Peihua Jiang, Ph.D., to the Center’s faculty.

Released: 24-Sep-2012 12:45 PM EDT
Tasteful Art: Scholar Ryan Bromley Visits Monell Center to Explore Role of Taste in Contemporary Art
Monell Chemical Senses Center

Ryan Bromley is the first Monell visiting scholar to explore the intersection of the sense of taste and artistic expression. Using a multidisciplinary approach, Bromley integrates information regarding taste perception to relevant findings from psycholinguistics, anthropology and philosophy to build a case for the validity of taste in art. He will present a seminar on September 27 entitled “Taste in Art: Out of Sight, Out of Mind?”


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