Stem cell biologist Sean J. Morrison, Ph.D., Howard Hughes Medical Institute Investigator and founding Director and Professor of the Children’s Medical Center Research Institute at UT Southwestern (CRI), has been elected by his peers as an associate member of the European Molecular Biology Organization (EMBO).
The arrival of summer marks the return of a cherished activity: backyard grilling. A UT Southwestern Medical Center toxicologist offers some cautionary guidelines to help you and your guests avoid food poisoning.
A consortium of government, industry, and nonprofit partners will fund gene therapy clinical trials for three different rare diseases at UT Southwestern Medical Center and Children’s Health, where scientists are working on gene therapies to treat neurodevelopmental disorders in children.
Most stroke patients taking the anticoagulant warfarin were no more likely than those not on the medication to experience a brain bleed when undergoing a procedure to remove a blood clot, UT Southwestern Medical Center researchers report in a new study. The findings, published in JAMA, could help doctors better gauge the risk of endovascular thrombectomy (EVT), potentially expanding the pool of eligible patients for this mainstay stroke treatment.
A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib. The finding, published in the journal Gastroenterology, may lead to alternative treatments for the most common form of liver cancer.
Japanese biochemist and molecular biologist Noboru Mizushima, M.D., Ph.D., has been named the inaugural recipient of the Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern Medical Center. Dr. Mizushima is an internationally recognized scientist who has made significant strides in unraveling the complex processes of mammalian autophagy, a fundamental cellular mechanism responsible for maintaining cellular health and functionality.
Mitochondria that power cellular activity fragment and change shape in breast cancer cells that migrate to the brain, an adaptation that appears necessary for the cells to survive, UT Southwestern Medical Center researchers report in a new study. The findings, published in Nature Cancer, could lead to new ways to prevent brain metastases, or the spread of cells from primary tumors to the brain.
UT Southwestern Medical Center and its William P. Clements Jr. University Hospital have been named an Antimicrobial Stewardship Center of Excellence by the Infectious Diseases Society of America (IDSA), recognizing a commitment to reducing infections caused by antimicrobial resistance.
The painful experience of having a kidney stone has become more common in recent years, including in Texas, part of the “Stone Belt” where hot weather can cause dehydration. But small dietary changes as well as drinking lots of water can help avert the discomfort, says a board-certified physician assistant in the Department of Urology at UT Southwestern Medical Center.
Peter Roland, M.D., Professor Emeritus of Otolaryngology-Head and Neck Surgery at UT Southwestern Medical Center, has been honored by the American Cochlear Implant Alliance with its 2023 Lifetime Achievement Award for his groundbreaking work in advancing the use and benefits of cochlear implants (CI).
Colorectal cancer is on the rise among younger adults. According to the American Cancer Society, the proportion of cases among people under 55 increased from 11% in 1995 to 20% in 2019, and it is now the leading cause of cancer-related deaths for men younger than 50.
A novel, minimally invasive surgical technique for correcting blepharoptosis – often called “droopy eyelid” – is more efficient and produces better results than the traditional method that uses sutures, according to a UT Southwestern Medical Center study. The findings, reported in the American Journal of Ophthalmology, may lead to a shift in how oculoplastic surgeons treat this common condition.
Anti-obesity medications, including semaglutide (Ozempic and Wegovy), can effectively help patients manage weight regained after bariatric surgery, a study led by UT Southwestern Medical Center researchers shows.
Ongoing research at UT Southwestern Medical Center exploring the ability of human heart cells to regenerate after a heart attack or other cardiovascular event will be accelerated by a new award from the National Institutes of Health.
Forty percent of critically ill children whose parents or other caregivers declined tracheostomies died within 24 months, and half of all deaths occurred within six weeks, researchers at UT Southwestern Medical Center and Children’s Medical Center Dallas found.
Depression is considered the most common complication of childbirth, and new mothers shouldn’t feel ashamed or embarrassed about seeking mental health care and treatments including therapy and medication, advised experts at UT Southwestern Medical Center.
If it hurts when you grip a cup of coffee, get up from a chair, or climb the stairs, you may have osteoarthritis, one of the most common types of arthritis. And though your achy joints seem to be telling you to take it easy, that’s exactly what you should not be doing.
UT Southwestern Medical Center researchers have identified hundreds of genomic variants associated with autism spectrum disorder (ASD) in East African families who have a markedly higher prevalence of the neurodevelopmental condition than other populations worldwide. The study, published in Cell Genomics, is the first to investigate the genetics of ASD in an African population, an important step toward decreasing racial and ethnic health disparities for this condition, the authors said.
A new type of developmental disability caused by mutations in a gene known as CBX1 has been discovered by a UT Southwestern Medical Center researcher and his colleagues. The findings, reported in Genetics in Medicine, an official journal of the American College of Medical Genetics and Genomics (ACMG), offer insight into the role this gene plays in development and could eventually lead to therapies for a range of related disorders.
Women with early-stage cervical cancer had significantly higher chances of developing catheter-associated urinary tract infections (CAUTIs) after radical hysterectomies if they were smokers or used a catheter for more than seven days post-surgery, UT Southwestern Medical Center researchers found in a study.
Seemingly healthy people whose blood contained antibodies associated with a condition called antiphospholipid syndrome (APS) were significantly more likely to experience a cardiovascular event such as a heart attack or stroke than those without, a study led by UT Southwestern Medical Center scientists shows
The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells. However, this process often goes awry and may be responsible for a new class of chromosomal abnormalities found in cancers and congenital disorders, UT Southwestern Medical Center scientists report in a new study. The discovery, published in Nature, sheds light on how cancer cells rapidly evolve genomic changes that fuel their proliferation.
It’s a common misconception that older adults need less sleep than those younger, but many get fewer hours due to insomnia and various health problems, including sleep apnea and heart trouble. In addition to a reduced quality of life, long-term health consequences of poor sleep include high blood pressure, weight gain, stroke, heart attack, diabetes, memory problems, and even increased risk of death, said Deborah Freeland, M.D., Assistant Professor of Internal Medicine and a member of UTSW’s Division of Geriatric Medicine.
Black and Hispanic adults at risk of developing cardiovascular disease are less likely to take statin drugs than white adults with the same risk factors, UT Southwestern Medical Center researchers reported in JAMA Cardiology.
Following the latest mass shooting at an outlet mall in Allen, Texas, on Saturday and other violent incidents across the country, parents may find themselves trying to navigate difficult conversations with their children. What to say is just as important as what not to say, according to experts at UT Southwestern Medical Center. Children are naturally curious and may have questions, or they may be worried about their own safety.
Thyrotoxic periodic paralysis (TPP), a rare neurological condition causing limbs to go limp, may be an underrecognized cause of paralysis in young Hispanic men, a review of data by UT Southwestern Medical Center endocrinologists shows.
UT Southwestern Medical Center is expanding its footprint to better serve the northwest Dallas region, offering primary care visits ranging from management of chronic health issues to women’s health exams at UT Southwestern Medical Center at Coppell.
UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.
Carlos L. Arteaga, M.D., Director of the Harold C. Simmons Comprehensive Cancer Center and Associate Dean of Oncology Programs at UT Southwestern Medical Center, has been named a research scholar for Susan G. Komen®, one of the world’s leading breast cancer organizations.
The National Academy of Sciences elected two more UT Southwestern Medical Center scientists in the fields of molecular genetics and physiology into its membership, one of the highest honors for American scientists. Russell DeBose-Boyd, Ph.D., Professor of Molecular Genetics, and Duojia Pan, Ph.D., Chair of Physiology and a Howard Hughes Medical Institute Investigator, were elected by their peers in recognition of the importance of their scientific discoveries.
Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical Center point to biological differences in the knee cartilage of male and female animals that could explain substantial variances in rates of osteoarthritis between the sexes and may eventually lead to tailored treatments that take these into account.
The resilience and coping abilities of patients who’ve had liver transplants vary and change over time and are often linked to sociodemographic factors including income, race, and education, a study led by UT Southwestern Medical Center researchers shows. The findings could lead to tailored interventions to optimize clinical and patient-centered outcomes among liver transplant recipients.
The rate of heart attacks, strokes, and other cardiovascular complications increased among patients hospitalized with COVID-19 between March 2020 and December 2021, according to a new study led by UT Southwestern Medical Center researchers. The rise came even as patients hospitalized with the virus tended to be younger and less likely to have had cardiovascular disease (CVD) as the pandemic wore on.
UT Southwestern Medical Center will lead a national multicenter clinical trial to test a treatment strategy for pediatric cancer patients that has shown promising results in adults. The trial will examine the effects of combining several chemotherapy agents with an immunotherapy drug in children with solid tumors that have recurred or shown no significant response after initial treatment.
While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin. A UT Southwestern physician who specializes in rheumatology says it’s essential to know what to look for.
Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells. The findings, published in Nature Communications, could lead to new ways to treat food poisoning caused by Vibrio parahaemolyticus.
Women with chronic hypertension and diabetes who were enrolled in an award-winning program for 12 months after childbirth were more likely to keep follow-up health care visits, which in turn led to improved care, according to initial findings of the program published in The Joint Commission Journal on Quality and Patient Safety.
A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft tissues after traumatic injury or surgery. The findings, published in Science Advances, could yield new ways to prevent this common complication, the researchers say.
Patients with sickle cell disease (SCD) who undergo total knee replacement are at higher risk for complications than non-SCD patients, according to a large-scale, retrospective study by researchers from UT Southwestern Medical Center and the University of Calgary. The study was published in Archives of Orthopaedic and Trauma Surgery.
The use of abdominal ice packs is a safe and effective way to help manage postoperative pain for patients who have had laparoscopic hysterectomies, an investigation by UT Southwestern clinicians has found.
Susan Hedayati, M.D., Director of Clinical and Population Health Research in Nephrology at UT Southwestern, has spent a career investigating the links between kidney disease and depression and developing methods to improve care from a patient-centric perspective for those with chronic kidney disease.
New technologies that can capture subtle changes in a patient’s voice may help physicians diagnose cognitive impairment and Alzheimer’s disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer’s Association publication Diagnosis, Assessment & Disease Monitoring.
Spring marks the arrival of baseball, and with it the risk of elbow injuries among young players. Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers. The most severe cases require reconstructive surgery, commonly known as Tommy John surgery.
Multiple studies have demonstrated that Black patients are significantly less likely than white patients to undergo invasive cardiovascular procedures. Prior research also has demonstrated substantial racial disparities in the use of implantable cardioverter-defibrillators (ICDs) that can be lifesaving for those at high risk for sudden cardiac death.
About 1 million people in the United States have Parkinson’s disease, a progressive neurological disorder that ranks second to Alzheimer’s among the most common neurodegenerative diseases. While many tend to associate Parkinson’s with hand tremors, it can cause a broad range of symptoms, affecting both motor and nonmotor functions.
Researchers led by a team at UT Southwestern Medical Center have created a statistical model to identify standards for typical, high, or low rates of bleeding after pediatric tonsillectomies. The findings, published in JAMA Otolaryngology-Head & Neck Surgery, could help doctors and hospitals improve outcomes for the third-most common pediatric surgery in the U.S.
After a school shooting like the one that occurred in Nashville, parents may find themselves trying to navigate difficult conversations with their children. What to say is just as important as what not to say, according to experts at UT Southwestern Medical Center. Children are naturally curious and may have questions, or they may be worried about their own safety.
Researchers at UT Southwestern Medical Center have been approved for an $18 million funding award from the nonprofit Patient-Centered Outcomes Research Institute (PCORI) to investigate ways to improve postpartum health among primarily low-income Black and Hispanic women.
A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases. The study, published in Nature Communications, offers key insights that could help identify new treatments for patients.
Patients with a family history of age-related macular degeneration (AMD), the leading cause of permanent vision loss in those older than 60, should visit an ophthalmologist by age 55 to be screened for signs of the disease, advises an expert at UT Southwestern Medical Center.
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