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Doctors try to improve the life of a four-year-old with a rare genetic disease and other patients like her

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For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly doubled survival for patients with diffuse midline glioma (DMG) or diffuse intrinsic pontine glioma (DIPG), compared to previous patients.

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A nephrologist explains the damage that this trend can cause

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Needs related to housing, transportation, food, social support and more can be identified through AI/ML techniques.

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People with chronic pain who take opioids have trouble finding multimodal pain care; insurance and provider education changes are needed, experts say.

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A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.

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A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

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A new study finds that the longer a person has type 2 diabetes, the more likely they may be to experience changes in brain structure. MRI results, researchers say, indicate the negative effects longstanding diabetes may have on brain health outcomes and emphasize the importance of preventing early onset type 2 diabetes.

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A study shows new steps toward more patients getting gene therapy

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A new study seeks to determine long-term satisfaction and regret following gender-affirming mastectomy.

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A collaborative research effort led by the University of Michigan and the Icahn School of Medicine at Mount Sinai has resulted in a nasal vaccine adjuvant that stops COVID infection in both young and old mice.

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From psychiatrists to experts in telehealth, public health and primary care, a range of reactions from University of Michigan faculty to the recent federal proposal for mental health policy, and related issues.

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A new study lends further weight to the idea that vision problems and dementia are linked. In a sample of nearly 3,000 older adults who took vision tests and cognitive tests during home visits, the risk of dementia was much higher among those with eyesight problems – including those who weren’t able to see well even when they were wearing their usual eyeglasses or contact lenses.

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Microwaving hard-boiled eggs is one of the latest TikTok trends that can harm your eyes

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Systemic sclerosis is the scaring of multiple organs within the body resulting in difficulty in functioning for these organs. The disease can become deadly if the organ scaring isn’t treated properly. Researchers at the University of Michigan Health System have identified a protein in the disease that may be a new target for treatment.

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Many need medical attention after experiencing burns from unsafe living conditions during the ongoing conflict with Russia.

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After the successful treatment, a patient shares his story to inspire others.

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Her ribs needed to be removed. Her care team searched far and wide and found the best possible treatment.

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Many families whose transgender children need gender-affirming care will need to drive much further than before because of laws and other actions passed since 2021 in 20 states, a new study shows. Half will need to drive an hour or more; 25% four hours each way.

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Taking more daily steps is associated improved health, including fewer symptoms and physical limitations, for people with heart failure, a new study finds. Researchers say it's one of the first studies to provide context to wearable device data from heart failure patients and sheds light on what physical activity data from a wearable device means at a population level as well as at the individual level.

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A social media trend inspired by the new film can cause pain and injuries if done for too long

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More than 1.4 million times a year, people with Alzheimer’s disease and other forms of dementia end up in emergency care, making up nearly 7% of all emergency visits for any reason by people over age 65, a new study shows. Compared with their peers who don’t have dementia, these patients have twice the rate of seeking emergency care after an accident or a behavioral or mental health crisis.

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A new single-state report looks at patterns of telehealth use by people with different forms of insurance before and during the pandemic, and could inform post-pandemic health policy.

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The majority of older adults with cognitive impairment are still driving, despite concerns raised by caregivers and others, a study finds. Researchers say it’s best for caregivers to start conversations surrounding driving earlier while the care recipient is able to understand and actively participate in the discussion.

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Researchers find indicators while studying hundreds of donor samples

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People who participate in cardiac rehabilitation have a decreased risk of death years after surgery, with a trend towards better outcomes in patients who attend more sessions, a study finds. Just over half of patients attended a single session of cardiac rehabilitation, and only 12% of those patients completed all 36 sessions. This occurred despite health systems referring patients to the program 94% of the time.

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Eighty percent of older adults see the benefit of tests that can give an early warning that a person’s memory and thinking abilities have started to decline, a new poll of people age 65 to 80 finds. And 60% think that health care providers should offer cognitive screening to all older adults every year

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Just 43% of parents have set their child up for a patient portal, mainly because they don't see a need, and others may not be optimizing portal use, suggests the University of Michigan Health C.S. Mott Children’s Hospital National Poll on Children’s Health.

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Researchers at University of Michigan developed a method to produce artificially grown miniature brains — called human brain organoids — free of animal cells that could greatly improve the way neurodegenerative conditions are studied and, eventually, treated. The work offers a solution to overcome Matrigel’s weaknesses.

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A new analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered.

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People with low incomes who live in states that expanded Medicaid got more of the kind of health care that can keep them healthier in the long run, compared with similar people in non-expansion states.

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A national study of blood ferritin and hemoglobin levels from tween, teen and young adult females suggests routine screening might be needed for iron deficiency and anemia.

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A new study finds that the minimum level of oxygen delivery during cardiopulmonary bypass may be lower than previously thought — meaning, there may be opportunities to avoid transfusing patients during cardiac surgical procedures. Researchers say cardiac surgical programs may be unnecessarily transfusing patients to prevent kidney injury.

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After an awake surgery to remove a cancerous brain tumor, a Michigan man is living “more deliberately” than ever — officiating a high school wrestling state championship and participating in research for a potential cure.

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Glioblastoma cells are poised near a “critical point” of order and disorder — meaning, the cells possess some form of large-scale coordination throughout the whole tumor that allows them to respond in practical unison to attempts to kill tumor cells, such as chemotherapy or radiation, a study suggests. Researchers say disrupting the large-scale organization of brain tumors may result in more powerful ways to treat and one day eliminate brain tumors.

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A new collective named the Great Lakes Clinical Center (GLCC) for the ARDS, Pneumonia and Sepsis (APS) Phenotyping Consortium will be intensely focused on examining the various mechanisms underpinning these conditions to better understand their impact on disease development, trajectory and outcomes.

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The National Cancer Institute has awarded the University of Michigan Rogel Cancer Center a grant worth $37 million over five years. At the same time, the center’s designation as a “comprehensive cancer center” was renewed.

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A newly created polygenic scoring system — one that weighs the combined effects of common genetic variants — can improve the ability to predict an individual’s risk of developing ALS, a study shows.

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Tummy aches are common among kids, with one in six parents in a new national poll saying their child experiences them at least once a month.

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Some pulmonary embolism patients may be hospitalized unnecessarily due to CT imaging results rather than clinical risk factors, a study finds. Roughly half of the low risk patients had CT imaging features that physicians consider “concerning”, and these patients fared just as well in the hospital as those whose CT scans showed no concerning findings.

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A U-M study examined the factors that went into decision-making around hospital transfers during the pandemic—and the moral distress that often resulted from it.

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Not enough people are getting genetic testing for cancer, according to recent research.

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Having the right care close to home is critical for many families.

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Summer sports are a great way to keep kids occupied, but too much activity can lead to weakened tendons

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73-year-old goes from not being able to walk to conquering seven miles a day

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A randomized controlled clinical trial of a device shows promise for quieting the phantom noises of tinnitus.