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Melanoma, GPER, Pregnancy, Estrogen, Immunotherapy

Penn Researchers Identify New Treatment Target for Melanoma

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Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Now, a research team from Perelman School of Medicine at the University of Pennsylvania says it may have determined the reason for the melanoma-protective effect.

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Nyu Langone, Rebecca Robbins, sleep app, health app, mobile phone app, Fitbit, Lose it, Apple Health

Who Uses Phone Apps to Track Sleep Habits? Mostly the Healthy and Wealthy in U.S.

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The profile of most Americans who use popular mobile phone apps that track sleep habits is that they are relatively affluent, claim to eat well, and say they are in good health, even if some of them tend to smoke.

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Heart Attack, Cardiac Arrest, Troponin, Blood Test

New Blood Test for Diagnosing Heart Attacks: A ‘Big Deal,’ with Caveats

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A longtime blood test that measures the likelihood of a cardiac event has become more sensitive and more precise. Why doctors and patients should be cautiously optimistic.

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Science

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cancer immunotherapy, mechanogenetics, CAR-T cell therapy, Ultrasound

Researchers Develop a Remote-Controlled Cancer Immunotherapy System

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells.

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Cochlear Implants, Deaf Children, Machine Learning, Language acquisition, MRI scan

Brain Imaging Predicts Language Learning in Deaf Children

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In a new international collaborative study between The Chinese University of Hong Kong and Ann & Robert H. Lurie Children’s Hospital of Chicago, researchers created a machine learning algorithm that uses brain scans to predict language ability in deaf children after they receive a cochlear implant. This study’s novel use of artificial intelligence to understand brain structure underlying language development has broad reaching implications for children with developmental challenges. It was published in the Proceedings of the National Academy of Sciences of the United States of America.

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Youth Using Alternative Tobacco Products Are More Likely to Smoke 1 Year Later

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Nonsmoking adolescents who use e-cigarettes, smokeless tobacco or tobacco water pipes are more likely to start smoking conventional cigarettes within a year, according to new research by UC San Francisco.

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Thryoid, Hypothyroid, Hypothyroidism, Hyperthyroid, Hyperthyroidism, Graves Disease, Autoimmune Disease

Hyperthyroidism vs. Hypothyroidism: What's the Difference?

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Loyola's Pauline Camacho, MD, Offers Tips for National Thyroid Awareness Month

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Mayo Clinic, 脊髓疾病, 神经内科, 多发性硬化症

研究表明,大多数未知脊髓疾病患者后来给予特定的诊断

Mayo Clinic的研究人员所进行的一项研究发现,大多数被怀疑患有原因不明脊髓炎的患者后来有另外一种具体的诊断。该研究发表在美国神经病学学会(American Academy of Neurology)的医学杂志 神经病学(Neurology)上。

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High Cholesterol, cholesterol management, Penn Medicine, perelman school of medicine , Health Insurance, Prescription Drug Benefit, Cardiology, Cardiovascular Medicine, PCSK9 Inhibitors, Cardiovascular Quality

Insurance Company Requirements Place Heavy Administrative Burden on Physicians Seeking to Prescribe New Cholesterol-Lowering Drugs

A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke. So-called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are self-injected medications approved for individuals with a genetic condition called familial hypercholesterolemia (FH) and those with atherosclerotic cardiovascular disease (ASCVD) who have high cholesterol despite receiving traditional statin medications and other treatments. Results of the study are published in Circulation: Cardiovascular Quality and Outcomes.

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Beth Israel Deaconess Medical Center, Pier Paolo Pandolfi, Ming Chen

Flipping the Switch: Dietary Fat, Changes in Fat Metabolism May Promote Prostate Cancer Metastasis

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Prostate tumors tend to be what scientists call “indolent” – so slow-growing and self-contained that many affected men die with prostate cancer, not of it. But for the percentage of men whose prostate tumors metastasize, the disease is invariably fatal. In a set of papers out today in the journals Nature Genetics and Nature Communications, researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms that promote metastasis in the mouse model and also implicated the typical Western high-fat diet as a key environmental factor driving metastasis.







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