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31-Jan-2023 6:00 AM EST
Financial coaching for parents in clinic leads to higher attendance at well-child health care visits for their young children
University of California, Los Angeles (UCLA), Health Sciences

Implementing financial coaching for parents of infants in a pediatric primary care setting reduced missed well-child care visit rates by half and significantly improved receipt of vaccinations at a timely age, according to a new community-partnered pilot study led by UCLA researchers.

Newswise: COVID by the numbers at UCLA Health: A million tests; 300,000 vaccines; 55,000 patients
Released: 27-Jan-2023 11:55 AM EST
COVID by the numbers at UCLA Health: A million tests; 300,000 vaccines; 55,000 patients
University of California, Los Angeles (UCLA), Health Sciences

Three years ago this month, the first case of COVID was diagnosed in the United States. Here are the latest figures on the pandemic, collected by UCLA Health hospitals and clinics.

24-Jan-2023 4:15 PM EST
Ignoring Native American data perpetuates misleading white ‘deaths of despair’ narrative
University of California, Los Angeles (UCLA), Health Sciences

An increase in "deaths of despair" in recent decades has been frequently portrayed as a phenomenon affecting white communities, but a new analysis in The Lancet shows the toll has been greater on Native Americans.

Newswise: UCLA researchers identify possible approach to prevent cancer from evolving to resist treatment
25-Jan-2023 3:05 PM EST
UCLA researchers identify possible approach to prevent cancer from evolving to resist treatment
University of California, Los Angeles (UCLA), Health Sciences

A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. Results are published online ahead of print in Cancer Discovery, a journal of the American Association for Cancer Research.

Released: 25-Jan-2023 6:05 AM EST
UCLA Health Tip Sheet January 25, 2023
University of California, Los Angeles (UCLA), Health Sciences

Below is a brief roundup of news and story ideas from the experts at UCLA Health.

Newswise: Commonly used antiretroviral drugs used to treat HIV and hepatitis B reduce immune cells’ energy production
Released: 18-Jan-2023 7:45 PM EST
Commonly used antiretroviral drugs used to treat HIV and hepatitis B reduce immune cells’ energy production
University of California, Los Angeles (UCLA), Health Sciences

New UCLA-led research suggests that antiretroviral drugs called TAF and TDF directly reduce energy production by mitochondria, structures inside cells that generate the power that cells use to function. Both drugs led to reduced cellular oxygen consumption rates, a measure of the ability of the mitochondria to produce energy, compared with controls.

10-Jan-2023 12:00 PM EST
MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer
University of California, Los Angeles (UCLA), Health Sciences

For men who undergo radiotherapy for localized prostate cancer, the precise targeting capabilities of MRI guidance resulted in fewer toxicities and better quality of life according to new research from UCLA Jonsson Comprehensive Cancer Center.

Newswise: The AVID college prep program leads to lower substance use, better health behaviors among high school students, UCLA-led research suggests
Released: 16-Dec-2022 12:15 PM EST
The AVID college prep program leads to lower substance use, better health behaviors among high school students, UCLA-led research suggests
University of California, Los Angeles (UCLA), Health Sciences

New UCLA-led research finds that a college preparatory program for youth experiencing educational inequities that operates in about 13% of U.S public high schools has a positive effect on students’ social networks, psycho-social outcomes, and health behaviors.  The findings, published Dec. 16 in the peer-reviewed journal Pediatrics, suggests that the Advancement via Individual Determination (AVID) program, aimed at increasing educational opportunities for under-represented and economically disadvantaged students, also significantly reduces substance use.

   
5-Dec-2022 10:05 PM EST
Racial, ethnic, socioeconomic disparities in insulin pump use have persisted over 20 years
University of California, Los Angeles (UCLA), Health Sciences

While use of insulin pumps to manage type 1 diabetes has grown over 20 years, there has been no improvement in racial, ethnic, and socioeconomic disparities in their use.

29-Nov-2022 7:55 PM EST
Long COVID patients and those with other illnesses experience similar, negative lingering effects during the pandemic
University of California, Los Angeles (UCLA), Health Sciences

Long COVID patients can experience many of the same lingering negative effects on their physical, mental, and social well-being as those experienced by people who become ill with other, non-COVID illnesses.

13-Nov-2022 8:00 PM EST
Researchers find genetic links between traits are often overstated
University of California, Los Angeles (UCLA), Health Sciences

Many estimates of how strongly traits and diseases share genetic signals may be inflated, and therefore some genetic correlations that have been attributed to shared biology may instead represent incorrect statistical assumptions.

Newswise: Weak evidence that interventions to boost housing affordability and stability promote better health
Released: 16-Nov-2022 9:00 AM EST
Weak evidence that interventions to boost housing affordability and stability promote better health
University of California, Los Angeles (UCLA), Health Sciences

Research finds low-certainty evidence that programs such as emergency rent assistance, legal assistance with waitlist priority for public housing, long-term rent subsidies and homeownership assistance lead to positive health outcomes.

9-Nov-2022 9:00 AM EST
First use of CRISPR to substitute genes to treat patients with cancer
University of California, Los Angeles (UCLA), Health Sciences

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

3-Nov-2022 12:55 PM EDT
Researchers Offer Roadmap for Identifying New Neuroprotective Treatments by Leveraging Sex Differences
University of California, Los Angeles (UCLA), Health Sciences

Sex differences in the aging brain may offer an enticing clue for researching more effective neuroprotective treatments, according to a new treatment development strategy laid out by UCLA researchers.

Released: 3-Nov-2022 11:05 AM EDT
UCLA's Operation Mend Healing the Wounds of War
University of California, Los Angeles (UCLA), Health Sciences

UCLA Health’s Operation Mend will celebrate 15 years of serving post 9/11-era wounded warriors and their families by walking with patients, their family members, physicians, staff, and supporters in the 2022 New York City Veterans Day Parade. They will be joining an estimated 25,000 marchers who gather to honor veterans, raise awareness of those who serve them, and to salute members of our currently serving military.

Newswise: UCLA Awarded a $21 Million Grant to Study the Health Impacts of the Aliso Canyon Gas Leak
Released: 2-Nov-2022 4:50 PM EDT
UCLA Awarded a $21 Million Grant to Study the Health Impacts of the Aliso Canyon Gas Leak
UCLA Fielding School of Public Health

A team of UCLA researchers has been awarded $20,993,333 by the Los Angeles County Department of Public Health to conduct the Aliso Canyon Disaster Health Research Study.

   
31-Oct-2022 6:00 PM EDT
Brain Changes in Autism Are Far More Sweeping Than Previously Known
University of California, Los Angeles (UCLA), Health Sciences

The new study finds brain-wide changes in virtually all of the 11 cortical regions analyzed, regardless of whether they are higher critical association regions – those involved in functions such as reasoning, language, social cognition and mental flexibility – or primary sensory regions.

Newswise: New Onset Chronic Kidney Disease in People with Diabetes Highest Among Ethnic, Racial Minorities
Released: 31-Oct-2022 6:00 AM EDT
New Onset Chronic Kidney Disease in People with Diabetes Highest Among Ethnic, Racial Minorities
University of California, Los Angeles (UCLA), Health Sciences

New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates were higher by approximately 60%, 40%, 33%, and 25% in the Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations, respectively, compared to white persons with diabetes.

Released: 27-Oct-2022 11:00 AM EDT
With $7m Grant From NIH, UCLA Scientists to Study if Brain Stimulation During Sleep Can Bolster Memory
University of California, Los Angeles (UCLA), Health Sciences

New research will aim to identify the electrical activity occurring as the brain receives information and then test whether targeted, gentle electrical stimulation can strengthen a specific memory.

Released: 25-Oct-2022 12:40 PM EDT
UCLA Researchers Identify Model for Studying Treatments Targeting MS Progression
University of California, Los Angeles (UCLA), Health Sciences

This model can be used by researchers to discover targets for treatments that improve walking, cognitive, coordination and visual disabilities in MS. 

21-Oct-2022 6:15 PM EDT
Telehealth Follow-Up Associated with Increased Returns and Hospitalizations After Emergency Department Visit
University of California, Los Angeles (UCLA), Health Sciences

Telehealth follow-up consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients compared with in-person follow-ups,

Released: 24-Oct-2022 10:05 AM EDT
Study Shows Inexpensive, Readily Available Chemical May Limit Impact of COVID-19
University of California, Los Angeles (UCLA), Health Sciences

Preclinical studies in mice that model human COVID-19 suggest that an inexpensive, readily available amino acid might limit the effects of the disease and provide a new off-the-shelf therapeutic option for infections with SARS-CoV-2 variants and perhaps future novel coronaviruses.

Released: 21-Oct-2022 4:45 PM EDT
New Analysis Led by UCLA Jonsson Comprehensive Cancer Center Finds Timing Androgen-Deprivation Therapy with Radiation Therapy Improves Outcomes in Localized Prostate Cancer
University of California, Los Angeles (UCLA), Health Sciences

In a large analysis of over 7,000 men treated internationally across 12 randomized trials, study shows that it is almost universally optimal for men to begin androgen deprivation therapy when starting radiation.

Released: 19-Oct-2022 4:05 PM EDT
UCLA researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme
University of California, Los Angeles (UCLA), Health Sciences

Research led by doctors and scientists at UCLA Jonsson Comprehensive Cancer Center and the UCLA Jane & Terry Semel Institute for Neuroscience & Human Behavior has identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme (GBM).

17-Oct-2022 6:00 AM EDT
Antigen testing for COVID can be a useful tool for healthcare systems’ return-to-work guidance
University of California, Los Angeles (UCLA), Health Sciences

A majority of health care workers remain antigen positive five to seven days following COVID-19 infection. Other healthcare systems can look to these findings as they implement their own return-to-work testing programs.

Newswise: UCLA-led study finds California’s greenhouse gas reductions could be wiped out by 2020 wildfires
Released: 17-Oct-2022 10:05 AM EDT
UCLA-led study finds California’s greenhouse gas reductions could be wiped out by 2020 wildfires
UCLA Fielding School of Public Health

A new analysis led by researchers with the University of California has found the 2020 wildfires in the state, the most disastrous wildfire year on record, put twice as much greenhouse gas emissions into the Earth’s atmosphere as the total reduction in such pollutants in California between 2003-2019.

11-Oct-2022 5:05 PM EDT
Researchers say brain images plus artificial intelligence may diagnose sleep apnea faster than current methods
University of California, Los Angeles (UCLA), Health Sciences

A combination of brain imaging data and machine learning can accurately diagnose obstructive sleep apnea (OSA) significantly faster than the standard methods now in use that are complex, costly, time-consuming, and can delay crucial treatment.

   
5-Oct-2022 5:05 PM EDT
Low-income charter school graduates had lower rates of problematic substance use as young adults, UCLA research suggests
University of California, Los Angeles (UCLA), Health Sciences

An 8-year study of nearly 1300 low-income adolescents in Los Angeles found that students who attended high performing charter high schools were much less likely to engage in risky substance use by the time they reached age 21. Males who attended the high-performing schools also had better physical health and lower obesity rates as young adults while females had substantially worse outcomes in those two areas.

   
Newswise: UCLA Fielding School of Public Health-led research demonstrates the importance of influenza vaccination globally
Released: 5-Oct-2022 12:05 PM EDT
UCLA Fielding School of Public Health-led research demonstrates the importance of influenza vaccination globally
UCLA Fielding School of Public Health

An international team of researchers has demonstrated that among patients hospitalized for influenza, those who were vaccinated had less severe infections, including reducing the odds for children requiring admittance to an intensive care unit by almost half.

29-Sep-2022 8:30 AM EDT
Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors
University of California, Los Angeles (UCLA), Health Sciences

Higher levels of a key inflammatory marker were related to older breast cancer survivors reporting cognitive problems, researchers found in one of the first long-term efforts to examine the potential link between chronic inflammation and cognition in older breast cancer survivors.

Newswise: Gut bacteria may contribute to susceptibility to HIV infection, UCLA-led research suggests
Released: 29-Sep-2022 8:05 PM EDT
Gut bacteria may contribute to susceptibility to HIV infection, UCLA-led research suggests
University of California, Los Angeles (UCLA), Health Sciences

New UCLA-led research suggests certain gut bacteria -- including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected. The findings, published in the peer-reviewed journal eBioMedicine, suggest that the gut microbiome could contribute to one’s risk for HIV infection, said study lead Dr.

Newswise: Making lab-grown brain organoids ‘brainier’
Released: 29-Sep-2022 2:50 PM EDT
Making lab-grown brain organoids ‘brainier’
University of California, Los Angeles (UCLA), Health Sciences

Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA center members discovered how to create more accurate, consistent brain organoids to develop treatments for neurological disorders.

26-Sep-2022 11:05 AM EDT
Researchers test cost-effective approach to early-cancer detection from cell-free DNA in blood samples
University of California, Los Angeles (UCLA), Health Sciences

Researchers at UCLA’s Jonsson Comprehensive Cancer Center and collaborating organizations report successful results from an experimental cancer-detection system that appears to have overcome some of the challenges of the "liquid biopsy" in a novel, cost-effective way.

Newswise: Vaccinating women infected with COVID during pregnancy prior to delivery provides antibodies to newborns
Released: 26-Sep-2022 6:00 AM EDT
Vaccinating women infected with COVID during pregnancy prior to delivery provides antibodies to newborns
University of California, Los Angeles (UCLA), Health Sciences

FINDINGS Women with COVID in pregnancy who are subsequently vaccinated after recovery, but prior to delivery, are more likely to pass antibodies on to the child than similarly infected but unvaccinated mothers are. Researchers who studied a mix of vaccinated and unvaccinated mothers found that 78% of their infants tested at birth had antibodies.

Released: 23-Sep-2022 12:05 PM EDT
New collaborative study to investigate sequential combinations of targeted inhibitors and immunotherapies against cancer
University of California, Los Angeles (UCLA), Health Sciences

The National Cancer Institute has awarded a five-year, $13.3 million grant to a collaborative study on sequential combinations of targeted inhibitors and immunotherapies against cancer.

Newswise: UCLA scientists awarded $10 million by NIH to study developing brain
Released: 22-Sep-2022 10:00 AM EDT
UCLA scientists awarded $10 million by NIH to study developing brain
University of California, Los Angeles (UCLA), Health Sciences

The research projects, part of the NIH's BRAIN Initiative, aim to shed light on the developing brain’s cellular infrastructure to better understand brain disorders.

Newswise: Artificial intelligence tools quickly detect signs of injection drug use in patients’ health records
Released: 21-Sep-2022 4:10 PM EDT
Artificial intelligence tools quickly detect signs of injection drug use in patients’ health records
University of California, Los Angeles (UCLA), Health Sciences

An automated process that combines natural language processing and machine learning identified people who inject drugs (PWID) in electronic health records more quickly and accurately than current methods that rely on manual record reviews.

   
Newswise: UCLA Fielding School of Public Health’s UCLA Center for Healthcare Management Names Executive-in-Residence
Released: 21-Sep-2022 10:05 AM EDT
UCLA Fielding School of Public Health’s UCLA Center for Healthcare Management Names Executive-in-Residence
UCLA Fielding School of Public Health

Jack Schlosser, a healthcare management veteran with more than four decades in the field, has been named Executive-in-Residence at the UCLA Fielding School of Public Health’s UCLA Center for Healthcare Management for the 2022-23 academic year.

   
Released: 16-Sep-2022 9:35 AM EDT
UCLA to Participate in Phase 3 Trial Evaluating Monkeypox Treatment
University of California, Los Angeles (UCLA), Health Sciences

The UCLA Clinical AIDS Research and Education (CARE) Center today announced its participation in STOMP (Study of Tecovirimat for Human Monkeypox Virus), or A5418, a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat for the treatment of human monkeypox. STOMP, which is being led by the AIDS Clinical Trials Group (ACTG), has been designed to learn as much as possible in a broad population of people with monkeypox.

Newswise: UCLA researcher awarded National Academy of Medicine prize for work on genetics of autism
15-Sep-2022 12:00 PM EDT
UCLA researcher awarded National Academy of Medicine prize for work on genetics of autism
University of California, Los Angeles (UCLA), Health Sciences

Dr. Daniel Geschwind was awarded the National Academy of Medicine’s top annual prize in mental health in recognition of his pioneering research and leadership in autism genetics.

Newswise: UCLA Study Links Length of REM Sleep to Animals’ Body Temperature
14-Sep-2022 5:00 PM EDT
UCLA Study Links Length of REM Sleep to Animals’ Body Temperature
University of California, Los Angeles (UCLA), Health Sciences

Data suggests a previously unobserved relationship between body temperature and REM sleep, with REM sleep appearing to act like a "thermostatically controlled brain heater.”

Newswise: UCLA Leads CDC-Funded Study on Effectiveness of Vaccines, Boosters in ‘Next Phase’ of COVID
Released: 13-Sep-2022 7:05 PM EDT
UCLA Leads CDC-Funded Study on Effectiveness of Vaccines, Boosters in ‘Next Phase’ of COVID
University of California, Los Angeles (UCLA), Health Sciences

The David Geffen School of Medicine at UCLA has been awarded a $13.6 million grant from the Centers for Disease Control and Prevention to continue to study the effectiveness of COVID-19 vaccines and the long-term impact of infection among U.S. health care workers. The new yearlong grant project follows the 2020–21 Preventing Emerging Infections Through Vaccine Effectiveness Testing study, or PREVENT I, which was among the first to demonstrate the real-world benefit of mRNA vaccines in preventing symptomatic infection following their authorization by the Food and Drug Administration.

Newswise: Dr. Timothy Miller Receives Congressional Medal of Honor Distinguished Citizen Award
Released: 12-Sep-2022 8:05 PM EDT
Dr. Timothy Miller Receives Congressional Medal of Honor Distinguished Citizen Award
University of California, Los Angeles (UCLA), Health Sciences

Dr. Timothy Miller was honored with the Congressional Medal of Honor Distinguished Citizen Award for his work reconstructing the faces of veterans severely disfigured during the wars in Iraq and Afghanistan.

Released: 9-Sep-2022 1:15 PM EDT
UCLA Health researchers analyze LA’s ‘stunningly diverse’ genetic ancestry to bring ethnic equity to precision medicine
University of California, Los Angeles (UCLA), Health Sciences

Analyzing genetic ancestry data from a large genomic repository – the UCLA ATLAS Precision Health Biobank – researchers have found a highly diverse patient population that’s consistent with the global diversity of Los Angeles – one of the most ethnically diverse cities in the world and an ideal location to pursue personalized, precision medicine for underrepresented populations.

Released: 8-Sep-2022 12:45 PM EDT
UCLA scientists developing test to detect breast implant ruptures
University of California, Los Angeles (UCLA), Health Sciences

Amid growing scrutiny of breast implant safety, a pair of UCLA scientists are developing a lab test aimed at detecting silicone implant ruptures which they think may also help explain why many women who received implants have later reported a constellation of systemic symptoms.

Newswise: State-level Earned Income Tax Credit linked to reduction in high-risk HIV behavior among single mothers
Released: 29-Aug-2022 5:05 PM EDT
State-level Earned Income Tax Credit linked to reduction in high-risk HIV behavior among single mothers
University of California, Los Angeles (UCLA), Health Sciences

UCLA research finds that a refundable State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC was associated with a 21% relative risk reduction in reported behavior that could put single mothers at high risk for becoming infected with HIV during the previous year. Also, a 10 percentage-point increase in SEITC was linked to a 38% relative reduction in the same reported high-risk behavior the previous year.



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