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Medicine

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CRISPR, Telomeres, dyskeratosis congenita

CRISPR sheds light on rare pediatric bone marrow failure syndrome

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Using the gene editing technology CRISPR, scientists have shed light on a rare, sometimes fatal syndrome that causes children to gradually lose the ability to manufacture vital blood cells. The research, at Washington University School of Medicine in St. Louis, suggests new lines of investigation into how to treat this condition — dyskeratosis congenita — which is characterized by shortened telomeres. Short telomeres lead to progressive DNA damage that accumulates over time.

Medicine

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Cancer, Colorectal Cancer, Chemoresistance, Immunotherapy

Cancer-Death Button Gets Jammed by Gut Bacterium

Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing a type of cancer cell death called apoptosis.

Medicine

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Connectome, Brain

Scientists Become Research Subjects in After-Hours Brain-Scanning Project

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Dosenbach, MD, PhD, an assistant professor of pediatric and developmental neurology at Washington University School of Medicine in St. Louis, and colleagues used imaging techniques to collect a massive amount of data on individual brains. Their work led to 10 individual-specific connectomes — detailed maps of neural brain connections that reveal spatial and organizational variability in brain networks.

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, diagnostic technology , Laboratory Medicine

Path-Tec: SpectraPath Brings Laboratories into the Future

A pain point many clinical labs will have to tackle in increasing priority over the next few years is cost reduction. As healthcare continues its transition from fee-for-service payments to value-based payments, facilities are anticipating a considerable decrease in Medicare reimbursements for clinical lab tests. With reimbursements shrinking and costs for everything from labor and specimen collection to transportation and logistics rising, labs are challenges to find new and better ways to maintain an acceptable cost structure while delivering the customer service and quality the market demands.

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, diagnostic technology , Laboratory Medicine

LGC Maine Standards Announces Release of VALIDATE® IBC Linearity and Calibration Verification Test Kit

LGC Maine Standards1 announces the release of VALIDATE® IBC linearity and calibration verification kit. The VALIDATE® IBC kit, in a human serum matrix, evaluates Total Iron Binding Capacity (TIBC) and Unsaturated Iron Binding Capacity (UIBC). Each VALIDATE® IBC kit, prepared using the CLSI EP06-A “equal delta” sample preparation, offers five distinct concentrations covering the reportable range of most chemistry analyzers. Each kit is liquid and ready-to-use. Simply dispense the product from each dropper bottle, directly into five sample cups, and run in replicates.

Medicine

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Concussion, Computers, post-concussion syndrome (PCS), Cell Phone, Krembil Neuroscience Centre, Canadian Concussion Centre, Dr. Charles Tator, Toronto Western Hospital

Non-LCD Technology Shows Promise for Return to Work/School for Postconcussion Syndrome Sufferers

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A pilot study conducted by the Canadian Concussion Centre has shown that using a non-LCD screen for computer tasks may decrease the risk of exacerbating symptoms in sufferers of post-concussion syndrome (PCS).

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, diagnostic technology , Laboratory Medicine

Auto Chemistry Analyzer-GS200

GS200 is a multi-functional benchtop clinical chemistry analyzer with a throughput up to 150 T/H. It features 24-hour non-stop cooling, stable heating for reaction, bilateral LIS etc., it is a compact chemistry solution for small laboratories and a back-up tool for mid-to-high end laboratories.

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, diagnostic technology , Laboratory Medicine

Specific Protein Analyzer-PA54

PA54 is a semi-auto analyzer for quantitative determination of specific proteins in blood, urine samples, including HbA1c, HS-CRP, CRP, ASO, CYS-C, RF, mALB, D-Dimer, IgM, IgG, IgA, C3, C4, etc. It's an ideal instrument designed for medium or small labs or backup analyzer in large labs.

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, diagnostic technology , Laboratory Medicine

Imegen, a Top Spanish Company for Genetic Analysis and Molecular Diagnostics Services and Kits

Imegen is a top Spanish Company for genetic analysis and molecular diagnostics services and kits. We offer A to Z flexible services and products including Sequencing, Arrays, MLPA, Real-time PCR, Digital PCR, NIPT, etc. Our internally developed sequencing technique, NextGeneDx, is based on NGS and differentiates by providing high resolution and coverage >100X of all coding regions of the targeted genes with specificity and robustness comparable to Sanger. Our recently launched Digital PCR kit, QUIMERA, is cutting-edge kit to follow up on transplant patients analysing haematopoietic chimerism. In addition to maximum precision and sensitivity, QUIMERA requires neither standard curves, nor pre-transplant samples, nor replicas. We are currently expanding on the international market and looking to collaborate with partners/ distributors in various regions and countries.

Medicine

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Aacc, diagnostic technology , 69th AACC Annual Scientific Meeting & Clinical Lab Expo, Laboratory Medicine

New Flow-Tight Liquid Transfer Pump with Linear Drive

KNF introduces the new solenoid-driven FL 10 diaphragm pump for OEM customers. With a nominal liquid flow rate of 100 mL/min, FL 10 features bi-directional flow-tightness without additional check valves, IP 65 protection, simple linear flow rate adjustment, a maintenance-free expected lifetime of 10,000h, and other key cost-saving attributes.







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