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18-Aug-2021 3:50 PM EDT
How Adolescents Used Drugs During the COVID-19 Pandemic
UC San Diego Health

Among adolescents ages 10 to 14 in the U.S, the overall rate of drug use remained relatively stable in the first six months of the COVID-19 pandemic. However, one change was a decreased use of alcohol, but an increased use of nicotine and misuse of prescription drugs.

Released: 23-Aug-2021 12:30 PM EDT
Eyes Provide Peek at Alzheimer’s Disease Risk
UC San Diego Health

Amyloid plaques found in the retinas of eyes may be an indicator of similar plaques in the brain, a hallmark of Alzheimer’s disease, and may provide a more visible biomarker for detecting disease risk.

Released: 19-Aug-2021 5:05 PM EDT
Girdin One’s Loins
UC San Diego Health

UC San Diego researchers detail how a ubiquitous signaling molecule plays a critical role in male fertility, orchestrating key steps that promote sperm motility, survival and fertilization success.

Released: 12-Aug-2021 3:50 PM EDT
Human Sperm Mutations that can Cause Disease in Children Identified
UC San Diego Health

UC San Diego researchers have described a new method for observing and counting mutations in sperm, and how to use this data to predict the likely impact of these mutations on future children.

10-Aug-2021 3:45 PM EDT
New Blood: Lab-Grown Stem Cells Bode Well for Transplants, Aging Research
UC San Diego Health

UC San Diego researchers develop a method to grow hematopoietic stem cells in culture, with clinical implications for bone marrow transplants and aging research.

Released: 11-Aug-2021 1:00 PM EDT
Most of UC San Diego’s COVID-19 Cases Detected Early by Wastewater Screening
UC San Diego Health

Part of UC San Diego’s Return to Learn program, wastewater screening helped prevent outbreaks by detecting 85 percent of cases early, allowing for timely testing, contact tracing and isolation.

Released: 9-Aug-2021 4:45 PM EDT
Young, Healthy Woman Suffers Brain Inflammation after Mild COVID-19 Infection
UC San Diego Health

UC San Diego Health physicians describe first known case of young, healthy adult experiencing central nervous system inflammation due to COVID-19, but without cognitive impairment.

Released: 5-Aug-2021 1:55 PM EDT
Organ Transplant Recipients Significantly Protected by COVID-19 Vaccination
UC San Diego Health

UC San Diego researchers report that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

Released: 2-Aug-2021 6:05 PM EDT
Rethinking Remdesivir
UC San Diego Health

UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.

Released: 28-Jul-2021 1:00 PM EDT
Obesity and Cardiovascular Factors Combine to Cause Cognitive Decline in Latinos
UC San Diego Health

Obesity is a major public health issue among Latinos, and a risk factor for Alzheimer’s disease. But in a new study, researchers at UC San Diego report that cardiometabolic abnormalities, such as hypertension, are more strongly associated with cognitive decline than obesity alone.

Released: 28-Jul-2021 11:45 AM EDT
UC San Diego Health Joins Clinical Trial to Treat Sudden Cardiac Arrest
UC San Diego Health

Cardiovascular physicians with UC San Diego Health have joined an international clinical trial utilizing a new Extravascular Implantable Cardioverter-Defibrillator (EV ICD) system to help treat sudden cardiac arrest.

Released: 27-Jul-2021 12:05 AM EDT
UC San Diego Health Ranked #1 by U.S. News & World Report
UC San Diego Health

UC San Diego Health, the region’s only academic health system, is ranked #1 in San Diego and #5 in California, placing it among the nation’s best hospitals, according to the 2021-2022 U.S. News & World Report survey. UC San Diego Health was ranked in the top 50 in 10 specialties.

Released: 23-Jul-2021 4:45 PM EDT
Senator Toni Atkins Visits Hospital to Recognize Plans for New Hillcrest Campus
UC San Diego Health

Senate President Pro Tempore Toni Atkins visited UC San Diego Medical Center today to recognize a $30 million allocation in the 2021-2022 California state budget that will support the redevelopment of the new Hillcrest hospital.

Released: 16-Jul-2021 4:05 PM EDT
3D “Assembloid” Shows How SARS-CoV-2 Infects Brain Cells
UC San Diego Health

Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

Released: 15-Jul-2021 2:30 PM EDT
Common Medication Used to Reduce Cholesterol Levels May Reduce COVID-19 Severity
UC San Diego Health

Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection.

Released: 12-Jul-2021 3:05 PM EDT
Selective, Toxin-Bearing Antibodies Could Help Treat Liver Fibrosis
UC San Diego Health

UC San Diego researchers discovered that immunotoxins targeting the protein mesothelin prevent liver cells from producing collagen, a precursor to fibrosis and cirrhosis, in mouse models of human disease.

Released: 12-Jul-2021 5:05 AM EDT
Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery
UC San Diego Health

Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

   
Released: 8-Jul-2021 11:00 AM EDT
UC San Diego Health First in Nation to Implant New Device for Chronic Back Pain
UC San Diego Health

Treatment provides non-opiate alternative that is minimally invasive with emphasis on functional restoration.

Released: 7-Jul-2021 11:45 AM EDT
How to Reduce Obesity among Latino Children, with Precision
UC San Diego Health

Researchers at UC San Diego Altman Clinical and Translational Research Institute have received $3 million to create a precision, community-based program to address specific health problems related to adverse childhood experiences that contribute to childhood obesity among Latinos.

Released: 6-Jul-2021 1:50 PM EDT
First Patients in San Diego County to Receive Lungs with Heart-Stopping Approach
UC San Diego Health

The lung transplant team at UC San Diego Health performed San Diego County’s first transplant surgery with lungs donated after cardiac death, an approach that could mean more opportunities to save the lives of those in critical need of new lungs.

Released: 6-Jul-2021 12:20 PM EDT
Colorectal Cancer Risk May Increase with Lower Exposure to UVB Light
UC San Diego Health

University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer.

30-Jun-2021 2:10 PM EDT
Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins
UC San Diego Health

UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.

Released: 1-Jul-2021 2:40 PM EDT
For Transplant Patients, COVID-19 Vaccination Presents a Different Uncertainty
UC San Diego Health

Researchers at UC San Diego Health have launched a pair of clinical trials to study the immune response of COVID-19 vaccinated transplant recipients of bone marrow and solid organs, such as the heart, lung, liver and kidney.

Released: 1-Jul-2021 12:25 PM EDT
New Chair Named for Department of Obstetrics, Gynecology & Reproductive Sciences
UC San Diego Health

After a nationwide search, Cynthia Gyamfi-Bannerman, MD, has been named chair of the Department of Obstetrics, Gynecology & Reproductive Sciences at University of California San Diego School of Medicine and UC San Diego Health.

Released: 29-Jun-2021 6:05 PM EDT
UC San Diego Health Adopts SMART Health Card for Digital Vaccine Records
UC San Diego Health

UC San Diego Health is now offering a verifiable digital vaccine record to its patients who have or will receive a COVID-19 vaccine. These secure online records, otherwise known as a SMART health card, can be accessed directly from the MyUCSDChart patient portal.

Released: 29-Jun-2021 1:40 PM EDT
Cooked Crustaceans, Cannabis and a Budder Way
UC San Diego Health

Researchers expose live lobsters to vaporized cannabis and confirm the crustaceans absorb THC. Whether the psychoactive compound affects behavior remains open question.

Released: 25-Jun-2021 10:40 AM EDT
Philanthropists Give $3.25 Million to Support Heart Disease Research
UC San Diego Health

Steven M. Strauss and Lise N. Wilson have gifted $3.25 million to UC San Diego Health Sciences to open a new research center geared toward creating novel treatment options that will slow or halt the progression of heart disease.

Released: 22-Jun-2021 12:25 PM EDT
Iris and Matthew Strauss Give $2 Million to Endow Faculty Chair at UC San Diego
UC San Diego Health

Longtime supporters of cancer research and patient care at Moores Cancer Center at UC San Diego Health have given University of California San Diego School of Medicine $2 million to establish the Iris and Matthew Strauss Chancellor’s Endowed Chair in Head and Neck Surgery.

Released: 17-Jun-2021 1:50 PM EDT
How Cells “Read” Artificial Ingredients Tossed into Genetic Recipe
UC San Diego Health

UC San Diego School of Medicine researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.

Released: 15-Jun-2021 11:30 AM EDT
Center Brings Doctors, Scientists Together to Improve Health of Mother and Child
UC San Diego Health

The Center for Perinatal Discovery at UC San Diego brings doctors and researchers together for clinical, translational and basic research to better understand maternal health, environmental exposures, fertility, pregnancy and the health of children.

9-Jun-2021 6:05 PM EDT
AI Predicts How Patients with Viral Infections, Including COVID-19, Will Fare
UC San Diego Health

UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.

Released: 10-Jun-2021 10:40 AM EDT
Researchers Test Model to Predict Drug Overdose Deaths in U.S.
UC San Diego Health

Researchers at UC San Diego, San Diego State University, and international collaborators have designed and validated a prediction model to signal counties at risk of future overdose death outbreaks.

Released: 9-Jun-2021 1:40 PM EDT
SARS-CoV-2 Detectable — Though Likely Not Transmissible — on Hospital Surfaces
UC San Diego Health

UC San Diego School of Medicine researchers discovered that SARS-CoV-2, or at least its genetic signature, abounds on hospital surfaces, often co-locating with one particular type of bacteria.

8-Jun-2021 1:50 PM EDT
How Your Phone Can Predict Depression and Lead to Personalized Treatment
UC San Diego Health

Researchers at University of California San Diego School of Medicine used a combination of modalities, such as measuring brain function, cognition and lifestyle factors, to generate individualized predictions of depression.

   
Released: 8-Jun-2021 12:55 PM EDT
Common Diabetes Drug Shows Promise as Treatment for COVID-19 Lung Inflammation
UC San Diego Health

Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.

Released: 3-Jun-2021 12:15 PM EDT
UC San Diego Health Begins Treating Multiple Myeloma with CAR T-cell Therapy
UC San Diego Health

As the first designated medical center in San Diego certified to offer this type of immunotherapy, UC San Diego Health will begin treating patients this month.

Released: 3-Jun-2021 10:55 AM EDT
Social Justice as Part of the Remedy for What Ails Us
UC San Diego Health

The T. Denny Sanford Institute for Empathy and Compassion has opened its newest center, focused on addressing issues of social justice in health care.

Released: 1-Jun-2021 1:20 PM EDT
Diet Plays Critical Role in NASH Progressing to Liver Cancer in Mouse Model
UC San Diego Health

Researchers at University of California San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.

Released: 27-May-2021 1:50 PM EDT
Noted Researcher and Scientific Leader Jack E. Dixon Retires
UC San Diego Health

Jack E. Dixon, whose distinguished and varied 48-year career ranged from helping reveal how cells communicate to becoming a renowned scientific leader at UC San Diego School of Medicine and Howard Hughes Medical Institute, is retiring.



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